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SOD1 / Cu-Zn SOD

superoxide dismutase 1, soluble

SOD1 / Cu-Zn SOD binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Gene Name: superoxide dismutase 1, soluble
Synonyms: SOD1, ALS, ALS1, Cu/Zn superoxide dismutase, HSod1, Homodimer, IPOA, SOD, soluble, SOD, Superoxide dismutase [Cu-Zn], Superoxide dismutase 1, Indophenoloxidase A, Superoxide dismutase, cystolic
Target Sequences: NM_000454 NP_000445.1 P00441

Publications (6)

1
Effect of specific activation of ?-aminobutyric acid receptor in vivo on oxidative stress-induced damage after extended hepatectomy. Gardner LB, Hori T, Chen F, Baine AM, Hata T, Uemoto S, Nguyen JH. Hepatology research : the official journal of the Japan Society of Hepatology. 2012 42:1131-40. (WB; Mouse) [Full Text Article] [PubMed:22583816] [PMC:PMC3438378]
2
Pretreatment of liver grafts in vivo by ?-aminobutyric acid receptor regulation reduces cold ischemia/warm reperfusion injury in rat. Hori T, Gardner LB, Hata T, Chen F, Baine AM, Uemoto S, Nguyen JH. Annals of transplantation : quarterly of the Polish Transplantation Society. 2013 18:299-313. (WB; Rat) [Full Text Article] [PubMed:23792534] [PMC:PMC3912510]
3
Oxidative stress and extracellular matrices after hepatectomy and liver transplantation in rats. Hori T, Uemoto S, Chen F, Gardner LB, Baine AM, Hata T, Kogure T, Nguyen JH. World journal of hepatology. 2014 6:72-84. (WB; Rat) [PubMed:24575166] [PMC:PMC3934637]
4
Hsp20-Mediated Activation of Exosome Biogenesis in Cardiomyocytes Improves Cardiac Function and Angiogenesis in Diabetic Mice. Wang X, Gu H, Huang W, Peng J, Li Y, Yang L, Qin D, Essandoh K, Wang Y, Peng T, Fan GC. Diabetes. 2016 October;65:3111-28. [Full Text Article] [PubMed:27284111] [PMC:PMC5033265]
5
Differential structural remodeling of the left-atrial posterior wall in patients affected by mitral regurgitation with or without persistent atrial fibrillation: a morphological and molecular study. Domenico Corradi, Sergio Callegari, Roberta Maestri, David Ferrara, Domenica Mangieri, Rossella Alinovi, Paola Mozzoni, Silvana Pinelli, Matteo Goldoni, Ylenia Adelaide Privitera, Veronica Bartoli, Ettore Astorri, Emilio Macchi, Augusto Vaglio, Stefano Benussi, Ottavio Alfieri. Journal of cardiovascular electrophysiology. 2012 March;23:271-9. [Full Text Article] [PubMed:21954878]
6
Cardioprotective effects of amiodarone in a rat model of epilepsy-induced cardiac dysfunction. Inas A Harb, Hend Ashour, Abeer Mostafa, Hala M El Hanbuli, Eman Hassan Nadwa. Clinical and experimental pharmacology & physiology. 2022 March;49:406-418. [Full Text Article] [PubMed:34796981]
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Antibodies (203)
Primary (203)
SOD1 / Cu-Zn SOD (203)
Human (124)
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No (203)
SOD1 / Cu-Zn SOD Antibody - Anti-SOD1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µg/$535
SOD1 / Cu-Zn SOD Antibody - Anti-SOD1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
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SOD1 / Cu-Zn SOD Mouse anti-Bovine Monoclonal (2F5) Antibody
Bovine
ELISA, IHC, IHC-Fr, IHC-P
Unconjugated
0.05 mg/$460
SOD1 / Cu-Zn SOD Antibody - Anti-SOD1 / SOD antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal Antibody
Xenopus, Rat, Hamster, Pig, Rabbit, Mouse, Dog, Sheep, Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µl/$505
SOD1 / Cu-Zn SOD Antibody - Anti-SOD1 antibody IHC of human liver, hephatocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal Antibody
Xenopus, Coral, Rat, Hamster, Pig, Rabbit, Mouse, Dog, Sheep, Bovine, Human, Monkey
ELISA, ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
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SOD1 / Cu-Zn SOD Mouse anti-Human Monoclonal (SOD9) Antibody
Human
ELISA, WB
Unconjugated
0.2 mg/$475; 0.5 mg/$583
SOD1 / Cu-Zn SOD Antibody - Confocal immunofluorescence of PANC-1 (left) and SKBR-3 (right) cells using SOD1 mouse monoclonal antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
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SOD1 / Cu-Zn SOD Mouse anti-Human Monoclonal (6F5) Antibody
Human
ELISA, Flo, ICC, IF, WB
Unconjugated
100 µl/$435
SOD1 / Cu-Zn SOD Antibody - Anti-SOD1 antibody IHC of human liver, hephatocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOD1 / Cu-Zn SOD Rabbit anti-Rat Polyclonal Antibody
Mouse, Bovine, Rat, Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
SOD1 / Cu-Zn SOD Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SOD1 / Cu-Zn SOD Mouse anti-Human Monoclonal (8B10) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
SOD1 / Cu-Zn SOD Antibody - SOD1 / Cu/Zn Superoxide Dismutase antibody SOD1(superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
SOD1 / Cu-Zn SOD Antibody - SOD1 / Cu/Zn Superoxide Dismutase antibody SOD1(superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
SOD1 / Cu-Zn SOD Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (aa 2-154) Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
SOD1 / Cu-Zn SOD Antibody - Western blot of Superoxide dismutase [Cu-Zn] antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 17 kDa. Observed band size: 32 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
SOD1 / Cu-Zn SOD Antibody - Anti-SOD1 / SOD antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50-1:100.
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SOD1 / Cu-Zn SOD Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (aa25-37) Antibody
Human
WB
Unconjugated
50 µl/$821
SOD1 / Cu-Zn SOD Antibody - Formalin-fixed and paraffin-embedded human colon carcinoma reacted with SOD1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (aa55-84) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
SOD1 / Cu-Zn SOD Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SOD1 / Cu-Zn SOD Rabbit anti-Pig Polyclonal (aa2-153) Antibody
Pig
ICC, IHC-P, IP, WB
Unconjugated
50 µl/$460
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SOD1 / Cu-Zn SOD Rabbit anti-Human Monoclonal (Preservative Free) (101) Antibody
Human
ELISA, ICC, IF
Unconjugated, Preservative Free
100 µl/$412
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SOD1 / Cu-Zn SOD Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat
ELISA, IHC, IP, WB
Unconjugated
100 µg/$884
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (aa100-144) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
500 µg/$393
SOD1 / Cu-Zn SOD Antibody - Detection of Human SOD1 by Immunohistochemistry. Sample: FFPE section of human osteosarcoma. Antibody: Affinity purified rabbit anti-SOD1 used at a dilution of 1:5000 (0.2 ug/ml). Detection: DAB.
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (aa54-104) Antibody
Human
IHC, WB
Unconjugated
10 µl/$295; 100 µl/$514
SOD1 / Cu-Zn SOD Antibody - Western blot analysis of lysate from Jurkat cells, using SOD-1 antibody.
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (aa36-85) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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SOD1 / Cu-Zn SOD Rabbit anti-Mouse Polyclonal (aa25-37) Antibody
Mouse, Rat
WB
Unconjugated
50 µl/$893
SOD1 / Cu-Zn SOD Antibody - SOD1 Antibody in Immunofluorescence (IF)
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SOD1 / Cu-Zn SOD Mouse anti-Human Monoclonal (6F5) Antibody
Mouse, Human
Flo, ICC, IF, WB
Unconjugated
100 µl/$541
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (aa55-84) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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SOD1 / Cu-Zn SOD Rabbit anti-Human Polyclonal (aa55-84) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).