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Vector Laboratories, Inc.
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SMC3 / HCAP

structural maintenance of chromosomes 3

Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.

Gene Name: structural maintenance of chromosomes 3
Synonyms: SMC3, Bamacan, CDLS3, CSPG6, HCAP, SMC-3, BAM, BMH, SMC protein 3, SMC3L1
Target Sequences: NM_005445 NP_005436.1 Q9UQE7

☰ Filters
Products
Antibodies (40)
Primary (40)
SMC3 / HCAP (40)
Human (39)
Mouse (19)
Rat (13)
Bat (7)
Bovine (8)
Chicken (4)
Chimpanzee (6)
Dog (7)
Gibbon (6)
Guinea pig (7)
Hamster (1)
Horse (7)
Monkey (6)
Orangutan (6)
Pig (7)
Rabbit (7)
Sheep (1)
Xenopus (6)
Zebrafish (6)
IHC (10)
IHC-P (7)
WB (36)
Flo (1)
ELISA (9)
ICC (1)
IP (5)
Peptide-ELISA (1)
rabbit (38)
mouse (2)
Product Group
IHCPlus (1)
IgG (20)
IgG1 (1)
IgG2b,k (1)
monoclonal mc (2)
polyclonal pc (37)
recombinant monoclonal rmc (1)
2F11 (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (22)
aa994-1181 (8)
aa402-430 (7)
pSer1083 (5)
aa1051-1100 (4)
aa215-264 (4)
aa1175-C-term (2)
aa1178-1216 (1)
aa325-375 (1)
pSer383 (1)
No (40)
SMC3 / HCAP Antibody - Anti-SMC3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa1051-1100) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SMC3 / HCAP Antibody - Anti-SMC3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa1051-1100) (HRP) Antibody
Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SMC3 / HCAP Antibody - Anti-SMC3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa1051-1100) (Biotin) Antibody
Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SMC3 / HCAP Antibody - Anti-SMC3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa1051-1100) (FITC) Antibody
Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
SMC3 / HCAP Antibody - Detection of Human SMC3 by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-SMC3 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa1175-C-term) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SMC3 / HCAP Antibody - SMC3 antibody IHC-paraffin. IHC(P): Mouse Intestine Tissue.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa1178-1216) Antibody
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
SMC3 / HCAP Antibody
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SMC3 / HCAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
SMC3 / HCAP Antibody - Western blot of recombinant SMC3 / HCAP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa994-1181) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
SMC3 / HCAP Antibody - 1:100 staining mouse spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SMC3 / HCAP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SMC3 / HCAP Antibody - IHC analysis of SMC3 using anti-SMC3 antibody. SMC3 was detected in paraffin-embedded section of human intestinal cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml mouse anti-SMC3 antibody overnight at 4°C. Biotinylated goat anti-mouse IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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SMC3 / HCAP Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
SMC3 / HCAP Antibody - Western blot of SMC3 expression in transfected 293T cell line by CSPG6 monoclonal antibody (M02), clone 2F11.
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SMC3 / HCAP Mouse anti-Human Monoclonal (2F11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa402-430) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa402-430) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa402-430) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa402-430) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa402-430) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa402-430) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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SMC3 / HCAP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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SMC3 / HCAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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SMC3 / HCAP Rabbit Recombinant Monoclonal Antibody
Flo, IP, WB
Unconjugated
20 µl/$299; 100 µl/$425
SMC3 / HCAP Antibody - Detection of human Phospho SMC3 (S1083) by western blot (WB). Samples: Whole cell lysate (50 µg) from HeLa cells treated with 100 µM etoposide and/or 100 µM phosphatase for 4 hours (+) or mock treated (-) cells. Antibodies: Affinity purified rabbit anti-Phospho SMC3 (S1083) antibodyused for WB at 1 µg/ml (upper panel); to detect total SMC3, rabbit anti-SMC3 was used for WB at 0.1 µg/ml (lower panel). Detection: Chemiluminescence with an exposure time of 3 minutes (upper panel) or 10 seconds (lower panel).
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SMC3 / HCAP Rabbit anti-Human Polyclonal (pSer1083) Antibody
Human
IP, WB
Unconjugated
10 µg/$295; 100 µl/$533
SMC3 / HCAP Antibody - Detection of Human SMC3 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma Antibody: Affinity purified rabbit anti-SMC3 used at a dilution of 1:250. Detection: DAB.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa1175-C-term) Antibody
Mouse, Human
IHC
Unconjugated
2.5 µg/$295; 100 µl/$532
SMC3 / HCAP Antibody - Detection of Human Phospho-SMC3 (S1083) by Immunohistochemistry. Samples: FFPE serial sections of human colon adenocarcinoma. Mock phosphatase treated section (left) or calf intestinal phosphatase-treated section (right) immunostained for Phospho-SMC3. Antibody: Affinity purified rabbit anti-Phospho-SMC3 (S1083) used at a dilution of 1:250. Detection: DAB staining using anti-rabbit IHC Antibody at a dilution of 1:100.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (pSer1083) Antibody
Mouse, Human
IHC
Unconjugated
0.5 µg/$295; 100 µl/$554
SMC3 / HCAP Antibody - Detection of Human and Mouse SMC3 by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug), 293T (T; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibody: Affinity purified rabbit anti-SMC3 antibody used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (aa325-375) Antibody
Mouse, Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
SMC3 / HCAP Antibody - Western blot of p-SMC3 (S1083) antibody at 1:500 dilution. Lane 1: A549 whole cell lysate. Lane 2: sp2/0 whole cell lysate. Lane 3: PC12 whole cell lysate.
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SMC3 / HCAP Rabbit anti-Human Polyclonal (pSer1083) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$328; 100 µl/$419
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).