SKP2

S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

SKP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms.

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Products

Antibodies (60)

Proteins (8)

ELISA Kits (5)

Type

Cell-Based (1)

Custom (1)

Over-Expression Lysate (2)

Primary (60)

Recombinant (6)

Sandwich (3)

Target

SKP2 (73)

Reactivity

Human (62)

Mouse (13)

Rat (8)

Bovine (4)

Chimpanzee (3)

Gibbon (3)

Monkey (3)

Pig (4)

Application

IHC (28)

IHC-P (15)

WB (54)

Flo (2)

ELISA (23)

ICC (5)

IF (10)

IP (16)

Peptide-ELISA (2)

Host

rabbit (50)

mouse (10)

Product Group

IHCPlus (3)

Isotype

IgG (28)

IgG1 (4)

IgG1,k (6)

Clonality

monoclonal mc (10)

polyclonal pc (50)

Clone

6G9D10 (2)

SKP2-8D9 (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (4)

APC (1)

APC Conjugated (3)

Biotin Conjugated (6)

Concentrated (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

Magnetic beads Conjugated (1)

PE Conjugated (3)

Preservative Free (2)

Sepharose Conjugated (1)

Unconjugated (34)

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Epitope

aa43-397 (8)

C-Terminus (5)

N-Terminus (4)

aa1-424 (4)

aa2-20 (2)

340-420 aa, C-terminal (1)

Amino Acid: 1-130 (1)

Pro399 (1)

aa1-50 (1)

aa156-185 (1)

aa221-425 (1)

aa366-415 (1)

aa50-100 (1)

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Publications

No (71)

Yes (2)

Sample Type

Adherent Cell Cultures (1)

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

Tag

6His-SUMO, N-terminus (1)

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ SKP2 Antibody LS-B2487

(5.0) Rating

(2) Publication(s)

Antibody:

SKP2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$485

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SKP2 Antibody (aa366-415) LS-C118576

Antibody:

SKP2 Rabbit anti-Human Polyclonal (aa366-415) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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Human SKP2 Protein (Recombinant 6His-SUMO, N-terminus) (Full Length) - LS-G21651

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Molecular Weight:

63.73 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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SKP2 Antibody (N-Terminus) LS-C171853

Antibody:

SKP2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$380

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SKP2 Antibody LS-C9421

Antibody:

SKP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$740

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SKP2 Antibody (HRP) LS-C548518

Antibody:

SKP2 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$982

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SKP2 Antibody (Biotin) LS-C528423

Antibody:

SKP2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$982

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SKP2 Antibody (FITC) LS-C538376

Antibody:

SKP2 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$982

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SKP2 Antibody (APC) LS-C518517

Antibody:

SKP2 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

APC Conjugated

Price:

100 µl/$982

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SKP2 Antibody (PE) LS-C656541

Antibody:

SKP2 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

PE Conjugated

Price:

100 µl/$982

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

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IHC-plus™ SKP2 Antibody (aa221-425) LS-B3361

(4.0) Rating

Antibody:

SKP2 Rabbit anti-Human Polyclonal (aa221-425) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

250 µl/$485

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IHC-plus™ SKP2 Antibody (aa1-50) LS-B15069

(4.0) Rating

Antibody:

SKP2 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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SKP2 Antibody (C-Terminus) LS-C352844

Antibody:

SKP2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Bovine, Pig, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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SKP2 Antibody LS-C826028

Antibody:

SKP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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SKP2 Antibody LS-C800551

Antibody:

SKP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SKP2 Antibody LS-C416139

Antibody:

SKP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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SKP2 Antibody (340-420 aa, C-terminal) LS-C386079

Antibody:

SKP2 Rabbit anti-Human Polyclonal (340-420 aa, C-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SKP2 Antibody (aa1-424) LS-C371329

Antibody:

SKP2 Rabbit anti-Human Polyclonal (aa1-424) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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SKP2 Antibody (aa1-424, HRP) LS-C371330

Antibody:

SKP2 Rabbit anti-Human Polyclonal (aa1-424) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP

• Unconjugated
• HRP

Select

SKP2 Antibody (N-Terminus) LS-C122446

Antibody:

SKP2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$564

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SKP2 Antibody (Pro399) LS-C176209

Antibody:

SKP2 Rabbit anti-Human Polyclonal (Pro399) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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SKP2 Antibody LS-C408248

Antibody:

SKP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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SKP2 Antibody LS-C832786

Antibody:

SKP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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Human SKP2 Protein (Recombinant GST) (Full Length) - LS-G30419

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

74.2 kDa

Price:

10 µg/$479; 25 µg/$670

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SKP2 Antibody (clone SKP2-8D9, Concentrated) LS-C202805

Antibody:

SKP2 Mouse anti-Human Monoclonal (Concentrated) (SKP2-8D9) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P

Format:

Unconjugated, Concentrated

Price:

100 µg/$527

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