Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
SIRT3 / Sirtuin 3
sirtuin 3
SIRT3 / Sirtuin 3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
| Gene Name: | sirtuin 3 |
| Family/Subfamily: | ADP-Ribosyltransferase , not assigned-ADP-Ribosyltransferase |
| Synonyms: | SIRT3, HSIRT3, Sir2-like 3, SIR2-like protein 3, SIR2L3, Sirtuin 3, Sirtuin type 3 |
| Target Sequences: | NM_012239 NP_036371.1 Q9NTG7 |
Publications (2)
1
FoxO1 mediates an autofeedback loop regulating SIRT1 expression. Xiong S, Salazar G, Patrushev N, Alexander RW. The Journal of biological chemistry. 2011 286:5289-99.
[PubMed:21149440]
[PMC:PMC3037641]
Related Antibodies: LS-C100489.
2
Integration of -catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity. Parker JA, Vazquez-Manrique RP, Tourette C, Farina F, Offner N, Mukhopadhyay A, Orfila AM, Darbois A, Menet S, Tissenbaum HA, Neri C. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 32:12630-40.
[PubMed:22956852]
Related Antibodies: LS-C100489.
☰ Filters
Products
Antibodies
(103)
Type
Primary
(103)
Target
SIRT3 / Sirtuin 3
(103)
Reactivity
Human
(83)
Mouse
(42)
Rat
(25)
Bovine
(6)
Dog
(9)
Guinea pig
(9)
Hamster
(7)
Horse
(9)
Monkey
(3)
Pig
(1)
Rabbit
(6)
Zebrafish
(3)
Application
IHC
(30)
IHC-P
(11)
WB
(97)
Flo
(1)
ELISA
(35)
ICC
(8)
IF
(6)
IP
(9)
Peptide-ELISA
(4)
Host
rabbit
(89)
mouse
(11)
goat
(2)
chicken
(1)
Product Group
IHCPlus
(2)
Isotype
IgG
(57)
IgG1
(2)
IgG2b
(1)
IgY
(1)
Clonality
monoclonal mc
(12)
polyclonal pc
(91)
Clone
6B2A1
(1)
6C12D1
(1)
Format
APC
(4)
APC Conjugated
(7)
Azide-free
(3)
Biotin Conjugated
(13)
Cy3 Conjugated
(4)
Cy7 Conjugated
(4)
FITC Conjugated
(13)
HRP Conjugated
(12)
PE Conjugated
(7)
Unconjugated
(43)
Epitope
aa126-382
(16)
C-Terminus
(10)
aa127-303
(8)
aa5-257
(8)
aa250-279
(7)
aa304-334
(7)
aa56-84
(7)
N-Terminus
(4)
aa152-201
(4)
aa126-399
(3)
aa20-130
(2)
320-400 aa, C-terminal
(1)
aa170-183
(1)
aa346-395
(1)
aa388-399
(1)
aa66-399
(1)
Publications
No
(102)
Yes
(1)
SIRT3 / Sirtuin 3 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
0.1 mg/$379
SIRT3 / Sirtuin 3 Goat anti-Mouse Polyclonal (aa170-183) Antibody
Mouse, Rat, Pig
IF, Peptide-ELISA, WB
Unconjugated
100 µg/$503
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal (aa250-279) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
SIRT3 / Sirtuin 3 Rabbit anti-Human Monoclonal Antibody
Rat, Human
ELISA, IP, WB
Unconjugated
100 µl/$688
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal (aa20-130) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
SIRT3 / Sirtuin 3 Mouse anti-Human Monoclonal (aa126-382) (PE) Antibody
Human
ICC, IP, WB
PE Conjugated
100 µl/$418; 200 µl/$507; 500 µl/$887; 1 ml/$1,051; 2 ml/$1,383; 5 ml/$2,591
SIRT3 / Sirtuin 3 Mouse anti-Human Monoclonal (6B2A1) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal (aa56-84) Antibody
Human
WB
Unconjugated
400 µl/$393
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal (aa20-130) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
SIRT3 / Sirtuin 3 Rabbit anti-Mouse Polyclonal (aa304-334) Antibody
Mouse, Hamster, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$393
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SIRT3 / Sirtuin 3 Rabbit anti-Mouse Polyclonal (aa304-334) Antibody
Mouse, Hamster
ELISA, IHC, WB
Unconjugated
200 µl/$734
SIRT3 / Sirtuin 3 Rabbit anti-Mouse Polyclonal (aa304-334) (Biotin) Antibody
Mouse, Hamster, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
SIRT3 / Sirtuin 3 Rabbit anti-Mouse Polyclonal (aa304-334) (FITC) Antibody
Mouse, Hamster, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
SIRT3 / Sirtuin 3 Rabbit anti-Mouse Polyclonal (aa304-334) (Azide-free) (HRP) Antibody
Mouse, Hamster, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
SIRT3 / Sirtuin 3 Rabbit anti-Mouse Polyclonal (aa304-334) (PE) Antibody
Mouse, Hamster, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal (aa250-279) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
SIRT3 / Sirtuin 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25
of 103
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
