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SERPING1 / C1 Inhibitor

serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.

Gene Name: serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Synonyms: SERPING1, C1-inhibiting factor, C1IN, C1 Inh, C1-INH, C1INH, C1NH, C1 Inhibitor, HAE1, HAE2, Plasma protease C1 inhibitor, C1 esterase inhibitor, Serpin G1
Target Sequences: NM_000062 NP_000053.2 P05155

Publications (1)

1
C1-inactivator is upregulated in glioblastoma. Förnvik K, Maddahi A, Persson O, Osther K, Salford LG, Nittby Redebrandt H. PloS one. 2017 September;12:e0183086. (Human) [Full Text Article] [PubMed:28880870] [PMC:PMC5589086] Related Antibodies: LS-C192710.

☰ Filters
Products
Proteins (22)
Over-Expression Lysate (4)
Recombinant (18)
SERPING1 / C1 Inhibitor (22)
SDS-PAGE (1)
No (22)
6His, C-terminus (4)
6His, N-terminus (1)
GST (1)
His (3)
His,C-terminus (1)
His-S (5)
Myc-DDK (Flag) (6)
Human (12)
Mouse (6)
Rat (2)
293T Cells (2)
CHO Cells (1)
E. coli (8)
HEK 293 Cells (5)
Human Cells (3)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (7)
Biologically active (2)
Select
E. coli
6His, N-terminus
56.4 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.6kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.9kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Select
CHO Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
49.4 kDa
50 µg/$268; 200 µg/$349
SERPING1 / C1 Inhibitor Protein - Purified recombinant protein SERPING1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
52.8 kDa
20 µg/$1,107
SERPING1 / C1 Inhibitor Protein - Purified recombinant protein SERPING1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
52.8 kDa
20 µg/$1,107
Select
E. coli
His-S
21.0 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Select
E. coli
His-S
13.3 kDa
10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383
Select
E. coli
His-S
16.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Select
E. coli
His-S
19.0 kDa
10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383
SERPING1 / C1 Inhibitor Protein - Recombinant Complement 1 Inhibitor By SDS-PAGE
Select
E. coli
His
15.0 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
SERPING1 / C1 Inhibitor Protein - Recombinant  Complement 1 Inhibitor By SDS-PAGE
Select
E. coli
His-S
17.0 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
SERPING1 / C1 Inhibitor Protein - 12.5% SDS-PAGE of human SERPING1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
80.52 kDa
10 µg/$479; 25 µg/$670
SERPING1 / C1 Inhibitor Protein
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The secreted recombinant human SERPING1 consists of 489 amino acids and predictes a molecular mass of 54.3 kDa. In SDS-PAGE under reducing conditions, it migrates with the apparent molecular mass of 110 kDa due to glycosylation.
100 µg/$480
SERPING1 / C1 Inhibitor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.19 kDa
100 µg/$494
SERPING1 / C1 Inhibitor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.19 kDa
100 µg/$710
SERPING1 / C1 Inhibitor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.19 kDa
20 µg/$150
SERPING1 / C1 Inhibitor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.19 kDa
20 µg/$215
SERPING1 / C1 Inhibitor Protein
Select
E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.9 kDa
10 µg/$288; 50 µg/$436
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.6 kDa
10 µg/$317; 50 µg/$524
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
54.3 kDa
100 µg/$926
Viewing 1-22 of 22 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).