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SERPINF1 / PEDF

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Gene Name: serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Synonyms: SERPINF1, EPC-1, OI12, PEDF, Serpin F1, PIG35, OI6
Target Sequences: NM_002615 NP_002606.3 P36955

Publications (4)

1
Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO. Journal of tissue engineering and regenerative medicine. 2013 August;7:642-653. [Full Text Article] [PubMed:22514096] Related Antibodies: LS-B2471.
2
Malignant ascites: a source of therapeutic protein against ovarian cancer?. Ribaux P, Britan A, Thumann G, Delie F, Petignat P, Cohen M. Oncotarget. 2019 October;10:5894-5905. [Full Text Article] [PubMed:31666922] [PMC:PMC6800269] Related Antibodies: LS-C100901.
3
CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization. Xiao Yang, Lian Zhao, Maria M Campos, Mones Abu-Asab, Davide Ortolan, Nathan Hotaling, Kapil Bharti, Wai T Wong. eLife. 2020 Apr;9:e55564. [Full Text Article] [PubMed:32234210] [PMC:PMC7156269]
4
Preterm birth prediction in asymptomatic women at mid-gestation using a panel of novel protein biomarkers: the Prediction of PreTerm Labor (PPeTaL) study. San Min Leow, Megan K W Di Quinzio, Zhen Long Ng, Claire Grant, Tal Amitay, Ying Wei, Moshe Hod, Penelope M Sheehan, Shaun P Brennecke, Nir Arbel, Harry M Georgiou. The Breast : official journal of the European Society of Mastology. 2020 May;;2:100084. [Full Text Article] [PubMed:33345955]
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Products
Antibodies (90)
Primary (90)
SERPINF1 / PEDF (90)
Human (47)
Mouse (41)
Rat (24)
Bat (3)
Bovine (1)
Chimpanzee (3)
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Guinea pig (3)
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IHC (15)
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IHC-P (11)
WB (63)
Flo (3)
ELISA (26)
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IF (1)
IP (11)
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rabbit (77)
mouse (11)
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sheep (1)
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monoclonal mc (13)
polyclonal pc (77)
013 (1)
061 (1)
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aa196-347 (1)
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No (88)
Yes (2)
SERPINF1 / PEDF Antibody - Anti-PEDF antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
SERPINF1 / PEDF Mouse anti-Human Monoclonal (aa196-347) Antibody
Human
ELISA, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$485
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SERPINF1 / PEDF Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, ICC, IHC, WB
HRP Conjugated
100 µl/$1,054
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SERPINF1 / PEDF Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, ICC, IHC, WB
Biotin Conjugated
100 µl/$1,054
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SERPINF1 / PEDF Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, ICC, IHC, WB
FITC Conjugated
100 µl/$1,054
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SERPINF1 / PEDF Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, ICC, IHC, WB
APC Conjugated
100 µl/$1,054
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SERPINF1 / PEDF Mouse anti-Human Monoclonal (PE) (10F12.2) Antibody
Human
ELISA, ICC, IHC, WB
PE Conjugated
100 µl/$1,054
SERPINF1 / PEDF Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SERPINF1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal (aa9-36) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
SERPINF1 / PEDF Antibody - Anti-PEDF antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 8 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SERPINF1 / PEDF Antibody - Anti-PEDF antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 8 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Dog, Guinea pig, Sheep, Rat, Pig, Horse, Bat, Chimpanzee, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SERPINF1 / PEDF Antibody - Anti-PEDF antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 8 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Dog, Guinea pig, Sheep, Rat, Pig, Horse, Bat, Chimpanzee, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SERPINF1 / PEDF Antibody - Anti-PEDF antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 8 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Dog, Guinea pig, Sheep, Rat, Pig, Horse, Bat, Chimpanzee, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$657
SERPINF1 / PEDF Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SERPINF1 / PEDF Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SERPINF1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal (aa279-306) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
SERPINF1 / PEDF Antibody - Western blot analysis of extract of various cells.
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
SERPINF1 / PEDF Antibody - Immunochemical staining of rat SERPINF1 in rat kidney with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
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SERPINF1 / PEDF Rabbit anti-Rat Polyclonal (Preservative Free) Antibody
Rat
ELISA, IHC-P, IP, WB
Unconjugated, Preservative Free
100 µl/$412
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
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SERPINF1 / PEDF Rabbit anti-Human Monoclonal (Preservative Free) (013) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
SERPINF1 / PEDF Antibody
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SERPINF1 / PEDF Rabbit anti-Mouse Polyclonal (aa19-389) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676
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SERPINF1 / PEDF Rabbit anti-Rat Monoclonal (Preservative Free) (061) Antibody
Rat
ELISA
Unconjugated, Preservative Free
100 µl/$412
SERPINF1 / PEDF Antibody - The cell lysates (10ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PEDF antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: 293T cell lysate Lane 2.: PEDF transfected 293T cell lysate
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SERPINF1 / PEDF Mouse anti-Human Monoclonal (AT13D9) Antibody
Human
ELISA, Flo, WB
Unconjugated
50 µl/$303; 100 µl/$365
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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SERPINF1 / PEDF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µl/$412
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SERPINF1 / PEDF Mouse anti-Human Monoclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).