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Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Gene Name: | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
Synonyms: | SERPINB5, Maspin, Peptidase inhibitor 5, PI5, Protease inhibitor 5 (maspin), Serpin B5, PI-5 |
Target Sequences: | NM_002639 NP_002630.2 P36952 |
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