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6737 Mowry Ave
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Customer Service: (800) 227-6666 / (650) 697-3600
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SDC1 / Syndecan 1 / CD138
syndecan 1
SDC1 / Syndecan 1 / CD138 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
| Gene Name: | syndecan 1 |
| Synonyms: | SDC1, CD138 antigen, SDC, SYND1, Syndecan, Syndecan 1, Syndecan-1, CD138, Syndecan proteoglycan 1 |
| Target Sequences: | NM_002997 NP_002988.3 P18827 |
Publications (3)
1
Increased CXCR3 Expression of Infiltrating Plasma Cells in Hunner Type Interstitial Cystitis. Akiyama Y, Morikawa T, Maeda D, Shintani Y, Niimi A, Nomiya A, Nakayama A, Igawa Y, Fukayama M, Homma Y. Scientific reports. 2016 6:28652. (IHC-P; Human)
[Full Text Article]
[PubMed:27339056]
[PMC:PMC4919639]
2
Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores the angiogenic homeostasis and suppresses tumor progression. Antonio G Solimando, Matteo C Da Vià, Patrizia Leone, Paola Borrelli, Giorgio A Croci, Paula Tabares, Andreas Brandl, Giuseppe Di Lernia, Francesco P Bianchi, Silvio Tafuri, Torsten Steinbrunn, Alessandra Balduini, Assunta Melaccio, Simona De Summa, Antonella Argentiero, Hilka Rauert-Wunderlich, Maria A Frassanito, Paolo Ditonno, Erik Henke, Wolfram Klapper, Roberto Ria, Carolina Terragna, Leo Rasche, Andreas Rosenwald, Martin K Kortüm, Michele Cavo, Domenico Ribatti, Vito Racanelli, Hermann Ein. Haematologica. 2020 April; [Full Text Article]
[PubMed:32354870]
[PMC:PMC8252928]
Related Antibodies: LS-B9360.
3
Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma. Zongwei Li, Huan Liu, Jin He, Zhiqiang Wang, Zheng Yin, Gichun You, Zhiming Wang, Richard E Davis, Pei Lin, P Leif Bergsagel, Elisabet E Manasanch, Stephen T C Wong, Nestor F Esnaola, Jenny C Chang, Robert Z Orlowski, Qing Yi, Jing Yang. The Breast : official journal of the European Society of Mastology. 2021 January;33:78-93e7. [Full Text Article]
[PubMed:33406405]
[PMC:PMC7799390]
Related Antibodies: LS-B9360.
☰ Filters
Products
Proteins
(19)
Type
Over-Expression Lysate
(2)
Recombinant
(17)
Target
SDC1 / Syndecan 1 / CD138
(19)
Publications
No
(19)
Tag
6His, C-terminus
(2)
Fc
(1)
Fc, C-terminus
(1)
GST
(2)
GST, N-terminus
(1)
His
(4)
His-GST
(3)
His-SUMO
(1)
His-T7
(1)
Myc-DDK (Flag)
(2)
TRX-6His, N-terminus
(1)
Species
Bovine
(1)
Human
(10)
Mouse
(2)
Rat
(5)
Source
293T Cells
(1)
E. coli
(8)
HEK 293 Cells
(1)
Human Cells
(5)
Mammalian Cells
(1)
Wheat Germ Extract
(2)
Yeast
(1)
Purification
Purified
(6)
Low Endotoxin Level
Low endotoxin level
(6)
Yeast
His
26.5 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.65kD
10 µg/$321; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51 kDa
10 µg/$288; 50 µg/$436
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Wheat Germ Extract
GST
58.9 kDa
10 µg/$479; 25 µg/$670
E. coli
His-SUMO
39.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
293T Cells
Myc-DDK (Flag)
32.52 kDa
20 µg/$150
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
25.6 kDa
100 µg/$721
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
26 kDa
100 µg/$721
SDC1 / Syndecan 1 / CD138 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122061
HEK 293 Cells
Myc-DDK (Flag)
32.52 kDa
100 µg/$494
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.7 kDa
10 µg/$314; 50 µg/$436
E. coli
GST
51.9 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
E. coli
TRX-6His, N-terminus
60 kDa
10 µg/$265; 50 µg/$315
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
51.2 kDa
100 µg/$721
E. coli
His-GST
56.6 kDa
50 µg/$442; 10 µg/$281; 200 µg/$882; 100 µg/$705; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
E. coli
His-GST
59.1 kDa
10 µg/$260; 50 µg/$335; 100 µg/$497; 200 µg/$622; 1 mg/$1,588; 500 µg/$1,185; 5 mg/$2,522; 2 mg/$1,760
E. coli
His-GST
56.2 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His-T7
30.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
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