RTN4 / Nogo

reticulon 4

Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing.

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Products

Antibodies (45)

Type

Primary (45)

Target

RTN4 / Nogo (45)

Reactivity

Human (33)

Mouse (21)

Rat (30)

Bat (6)

Bovine (7)

Chicken (3)

Chimpanzee (6)

Dog (7)

Gibbon (6)

Guinea pig (3)

Horse (6)

Monkey (9)

Orangutan (6)

Pig (7)

Rabbit (7)

Sheep (7)

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Application

IHC (18)

IHC-P (8)

WB (40)

Flo (2)

ELISA (17)

ICC (1)

IF (2)

IP (6)

Peptide-ELISA (4)

Host

rabbit (39)

mouse (1)

goat (1)

rabbit-new zealand white (1)

rat (1)

sheep (2)

Product Group

IHCPlus (4)

Isotype

IgG (34)

IgG2b (2)

Clonality

monoclonal mc (2)

polyclonal pc (43)

Clone

11n137 (1)

Format

APC Conjugated (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (34)

Epitope

N-Terminus (4)

aa254-303 (4)

aa81-130 (4)

C-Terminus (3)

Internal (3)

Glu499 (1)

N-Terminal (1)

aa1-183 (1)

aa1-200 (1)

aa1050-1100 (1)

aa14-30 (1)

aa2-172 (1)

aa28-58 (1)

aa450-499 (1)

aa460-510 (1)

aa501-515 (1)

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Publications

No (44)

Yes (1)

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IHC-plus™ RTN4 / Nogo Antibody (aa14-30) LS-B6516

(5.0) Rating

(2) Publication(s)

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal (aa14-30) Antibody

Reactivity:

Mouse, Rat, Pig, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ RTN4 / Nogo Antibody LS-B2708

(4.0) Rating

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$440

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IHC-plus™ RTN4 / Nogo Antibody (aa501-515) LS-B4168

(4.0) Rating

Antibody:

RTN4 / Nogo Goat anti-Human Polyclonal (aa501-515) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µg/$440

Select

RTN4 / Nogo Antibody (C-Terminus) LS-C122207

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$564

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RTN4 / Nogo Antibody (aa1050-1100) LS-C829654

Antibody:

RTN4 / Nogo Rabbit-New Zealand White anti-Human Polyclonal (aa1050-1100) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

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RTN4 / Nogo Antibody (Glu499) LS-C177253

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal (Glu499) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

IHC-plus™ RTN4 / Nogo Antibody LS-B2709

(4.0) Rating

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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RTN4 / Nogo Antibody (C-Terminus) LS-C37528

Antibody:

RTN4 / Nogo Rabbit anti-Rat Polyclonal (C-Terminus) Antibody

Reactivity:

Rat

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

Select

RTN4 / Nogo Antibody (aa254-303, FITC) LS-C449279

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal (aa254-303) (FITC) Antibody

Reactivity:

Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

Select

RTN4 / Nogo Antibody (PE) LS-C656327

Antibody:

RTN4 / Nogo Rabbit anti-Rat Polyclonal (PE) Antibody

Reactivity:

Rat

Applications:

IP, WB

Format:

PE Conjugated

Price:

100 µl/$1,017

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RTN4 / Nogo Antibody LS-C753465

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

RTN4 / Nogo Antibody LS-C753464

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

RTN4 / Nogo Antibody (Internal) LS-C384936

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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RTN4 / Nogo Antibody LS-C405962

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

RTN4 / Nogo Antibody (aa450-499) LS-C291716

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal (aa450-499) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

RTN4 / Nogo Antibody (Internal) LS-C358308

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

RTN4 / Nogo Antibody LS-C807245

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

RTN4 / Nogo Antibody (aa460-510) LS-C94353

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal (aa460-510) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

500 µg/$393

Select

RTN4 / Nogo Antibody LS-C402720

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

RTN4 / Nogo Antibody (N-Terminus) LS-C191470

Antibody:

RTN4 / Nogo Sheep anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µg/$930

Select

RTN4 / Nogo Antibody LS-C37526

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$832

Select

RTN4 / Nogo Antibody (N-Terminus) LS-C37534

Antibody:

RTN4 / Nogo Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

Select

RTN4 / Nogo Antibody (aa1-183, clone 11n137) LS-C184855

Antibody:

RTN4 / Nogo Rat anti-Mouse Monoclonal (aa1-183) (11n137) Antibody

Reactivity:

Mouse

Applications:

IHC

Format:

Unconjugated

Price:

100 µg/$872

Select

RTN4 / Nogo Antibody (aa1-200) LS-C131011

Antibody:

RTN4 / Nogo Sheep anti-Human Polyclonal (aa1-200) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$930

Select

RTN4 / Nogo Antibody (aa2-172) LS-C37525

Antibody:

RTN4 / Nogo Mouse anti-Rat Monoclonal (aa2-172) Antibody

Reactivity:

Rat

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$884

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