Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Location


Corporate Headquarters

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Telephone Numbers



Customer Service: (800) 227-6666 / (650) 697-3600


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

PVRL4 / Nectin 4

poliovirus receptor-related 4

PVRL4 / Nectin 4 is a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Gene Name: poliovirus receptor-related 4
Synonyms: PVRL4, EDSS1, Nectin 4, Ig superfamily receptor LNIR, Poliovirus receptor-like 4, LNIR, Nectin-4, Poliovirus receptor-related 4
Target Sequences: NM_030916 NP_112178.2 Q96NY8

Publications (1)

1
Adherens junction protein nectin-4 is the epithelial receptor for measles virus. Mhlebach MD, Mateo M, Sinn PL, Prfer S, Uhlig KM, Leonard VH, Navaratnarajah CK, Frenzke M, Wong XX, Sawatsky B, Ramachandran S, McCray PB, Cichutek K, von Messling V, Lopez M, Cattaneo R. Nature. 2011 480:530-3. (Flo; Human) [Full Text Article] [PubMed:22048310] [PMC:PMC3245798] Related Antibodies: LS-C37483.

☰ Filters
Products
Antibodies (30)
Primary (30)
PVRL4 / Nectin 4 (30)
Human (29)
Mouse (6)
Rat (1)
IHC (3)
IHC-P (2)
WB (26)
Flo (1)
ELISA (16)
IF (3)
Peptide-ELISA (2)
rabbit (28)
mouse (1)
rat (1)
Product Group
IHCPlus (1)
IgG (17)
IgG2a (1)
IgG2b (1)
monoclonal mc (2)
polyclonal pc (28)
337516 (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (15)
aa31-317 (8)
aa239-266 (7)
290-370 aa, Internal (1)
aa27-351 (1)
aa312-361 (1)
aa371-510 (1)
No (29)
Yes (1)
PVRL4 / Nectin 4 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa371-510) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
60 µl/$460
Select
PVRL4 / Nectin 4 Mouse anti-Human Monoclonal (aa27-351) (337516) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$962
Select
PVRL4 / Nectin 4 Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$896
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
PVRL4 / Nectin 4 Antibody - Immunohistochemistry Dilution at 1:400 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PVRL4 / Nectin 4 Antibody - Western blot analysis of lysates from NIH/3T3 cells, using PVRL4 Antibody. The lane on the right is blocked with the synthesized peptide.
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa312-361) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (290-370 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$341
PVRL4 / Nectin 4 Antibody - Staining NIH-3T3 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PVRL4 / Nectin 4 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using PVRL4 Polyclonal Antibody at dilution of 1:40.
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PVRL4 / Nectin 4 Antibody - PVRL4 Antibody western blot of A2058 cell line lysates (35 ug/lane). The PVRL4 antibody detected the PVRL4 protein (arrow).
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) Antibody
Human
WB
Unconjugated
400 µl/$393
PVRL4 / Nectin 4 Antibody - Western blot of PVRL4 / Nectin 4 antibody.
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa31-317) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
PVRL4 / Nectin 4 Antibody - Western blot of PVRL4 / Nectin 4 antibody.
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa31-317) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
PVRL4 / Nectin 4 Antibody - Western blot of PVRL4 / Nectin 4 antibody.
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa31-317) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
PVRL4 / Nectin 4 Antibody - Western blot analysis of Nectin-4/PVRL4 expression in MCF-7 whole cell lysates and MM453 whole cell lysates. Nectin-4/PVRL4 at 66KD was detected using rabbit anti-Nectin-4/PVRL4 Antigen Affinity purified polyclonal antibody at 0.5 ug/ml. The blot was developed using chemiluminescence (ECL) method.
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
PVRL4 / Nectin 4 Antibody - Western blot analysis of Nectin 4 expression in Hela (A), MCF7 (B), MEF (C), PC12 (D) whole cell lysates.
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
PVRL4 / Nectin 4 Antibody - Western blot testing of human 1) MCF7 and 2) MM453 lysate with Nectin-4 antibody at 0.5ug/ml. Expected molecular weight ~55 kDa (unmodified), ~66 kDa (glycosylated).
Select
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$575
Viewing 1-25 of 30 product results


Filtered By:
Products: Antibodies


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).