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PVRL4 / Nectin 4
poliovirus receptor-related 4
PVRL4 / Nectin 4 is a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
| Gene Name: | poliovirus receptor-related 4 |
| Synonyms: | PVRL4, EDSS1, Nectin 4, Ig superfamily receptor LNIR, Poliovirus receptor-like 4, LNIR, Nectin-4, Poliovirus receptor-related 4 |
| Target Sequences: | NM_030916 NP_112178.2 Q96NY8 |
Publications (1)
1
Adherens junction protein nectin-4 is the epithelial receptor for measles virus. Mhlebach MD, Mateo M, Sinn PL, Prfer S, Uhlig KM, Leonard VH, Navaratnarajah CK, Frenzke M, Wong XX, Sawatsky B, Ramachandran S, McCray PB, Cichutek K, von Messling V, Lopez M, Cattaneo R. Nature. 2011 480:530-3. (Flo; Human)
[Full Text Article]
[PubMed:22048310]
[PMC:PMC3245798]
Related Antibodies: LS-C37483.
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PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa371-510) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
60 µl/$460
PVRL4 / Nectin 4 Mouse anti-Human Monoclonal (aa27-351) (337516) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$962
PVRL4 / Nectin 4 Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$896
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
35.3kD
10 µg/$277; 50 µg/$395; 500 µg/$1,203
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa312-361) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (290-370 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$341
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa239-266) Antibody
Human
WB
Unconjugated
400 µl/$393
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa31-317) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal (aa31-317) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
PVRL4 / Nectin 4 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$575
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