PSMB8 / LMP7

proteasome (prosome, macropain) subunit, beta type, 8

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.

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Products

Antibodies (50)

Proteins (13)

ELISA Kits (11)

Type

Custom (6)

Over-Expression Lysate (4)

Primary (50)

Recombinant (9)

Sandwich (5)

Target

PSMB8 / LMP7 (74)

Reactivity

Human (38)

Mouse (13)

Rat (15)

Bovine (8)

Dog (1)

Monkey (1)

Pig (1)

Application

IHC (11)

IHC-P (6)

WB (49)

Flo (7)

ELISA (10)

ICC (4)

IF (10)

IP (3)

Peptide-ELISA (2)

Host

rabbit (44)

mouse (5)

goat (1)

Product Group

IHCPlus (2)

Isotype

IgG (14)

IgG1 (4)

IgG2a,k (1)

Clonality

monoclonal mc (5)

polyclonal pc (45)

Clone

1A5 (2)

1B3 (1)

LMP7-1 (1)

Format

96-Well Microplate (2)

96-Well Strip Plate (9)

APC (3)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (5)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (4)

Preservative Free (1)

Unconjugated (21)

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Epitope

aa75-261 (8)

aa75-272 (8)

aa80-261 (8)

aa8-36 (7)

N-Terminus (4)

aa125-175 (1)

aa226-276 (1)

aa263-276 (1)

aa52-276 (1)

Publications

No (74)

Sample Type

Cell Lysates (2)

Cell Supernatant (2)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

Tag

10His-SUMO, N-terminus + Myc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His-T7 (3)

Myc-DDK (Flag) (6)

Species

Human (9)

Mouse (1)

Rat (1)

Source

293T Cells (2)

E. coli (5)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (3)

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IHC-plus™ PSMB8 / LMP7 Antibody LS-B15635

(4.0) Rating

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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PSMB8 / LMP7 Antibody (clone 1A5) LS-C758962

Antibody:

PSMB8 / LMP7 Mouse anti-Human Monoclonal (1A5) Antibody

Reactivity:

Rat, Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

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PSMB8 / LMP7 Antibody (clone 1B3) LS-C133416

Antibody:

PSMB8 / LMP7 Mouse anti-Human Monoclonal (1B3) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µg/$423

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PSMB8 / LMP7 Antibody (clone 1A5) LS-C169405

Antibody:

PSMB8 / LMP7 Mouse anti-Human Monoclonal (1A5) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

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PSMB8 / LMP7 Antibody LS-C812686

Antibody:

PSMB8 / LMP7 Mouse anti-Human Monoclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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PSMB8 / LMP7 Antibody LS-C482808

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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IHC-plus™ PSMB8 / LMP7 Antibody (aa263-276) LS-B9206

(4.0) Rating

Antibody:

PSMB8 / LMP7 Goat anti-Human Polyclonal (aa263-276) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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PSMB8 / LMP7 Antibody (Preservative Free) LS-C820428

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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PSMB8 / LMP7 Antibody LS-C755311

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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PSMB8 / LMP7 Antibody (aa52-276) LS-C186312

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (aa52-276) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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Human PSMB8 / LMP7 Protein (Recombinant His) - LS-G2048

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human PSMB8 / LMP7 Protein (Recombinant His-T7) (aa75-261) - LS-G13995

Source:

E. coli

Tag:

His-T7

Molecular Weight:

24.5 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209

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PSMB8 / LMP7 Antibody LS-C769916

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PSMB8 / LMP7 Antibody (aa8-36) LS-C324358

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (aa8-36) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

200 µl/$734

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PSMB8 / LMP7 Antibody (aa8-36, Biotin) LS-C267294

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (aa8-36) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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PSMB8 / LMP7 Antibody (aa8-36, FITC) LS-C267295

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (aa8-36) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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PSMB8 / LMP7 Antibody (aa8-36, APC) LS-C267293

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (aa8-36) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

APC Conjugated

Price:

200 µl/$952

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PSMB8 / LMP7 Antibody (aa8-36, Azide-free, HRP) LS-C267298

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (aa8-36) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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PSMB8 / LMP7 Antibody (aa8-36, PE) LS-C267297

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (aa8-36) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

PSMB8 / LMP7 Antibody LS-C803562

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PSMB8 / LMP7 Antibody (clone LMP7-1) LS-C343797

Antibody:

PSMB8 / LMP7 Mouse anti-Human Monoclonal (LMP7-1) Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$560

Select

PSMB8 / LMP7 Antibody (aa8-36) LS-C162235

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (aa8-36) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

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PSMB8 / LMP7 Antibody (aa75-272) LS-C295096

Antibody:

PSMB8 / LMP7 Rabbit anti-Mouse Polyclonal (aa75-272) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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PSMB8 / LMP7 Antibody (N-Terminus) LS-C201504

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PSMB8 / LMP7 Antibody (aa125-175) LS-C762746

Antibody:

PSMB8 / LMP7 Rabbit anti-Human Polyclonal (aa125-175) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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