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Newark, CA 94560
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Prohibitin 2 / PHB2
prohibitin 2
Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases By similarity. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
| Gene Name: | prohibitin 2 |
| Family/Subfamily: | Transcription factor |
| Synonyms: | PHB2, BCAP37, BAP, D-prohibitin, p22, Prohibitin-2, B-cell associated protein, Bap37, PNAS-141, Prohibitin 2, REA |
| Target Sequences: | NM_007273 NP_001138303.1 Q99623 |
Publications (2)
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