PRF1 / Perforin

perforin 1 (pore forming protein)

Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

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Products

Antibodies (67)

ELISA Kits (26)

Proteins (16)

Type

Competitive EIA (2)

Custom (2)

Over-Expression Lysate (4)

Primary (67)

Recombinant (12)

Sandwich (19)

Sandwich CLIA (3)

Target

PRF1 / Perforin (109)

Reactivity

Human (54)

Mouse (21)

Rat (19)

Bovine (5)

Chicken (1)

Gibbon (3)

Guinea pig (1)

Horse (3)

Monkey (1)

Pig (3)

Porcine (1)

Rabbit (1)

Sheep (1)

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Application

IHC (14)

IHC-Fr (10)

IHC-P (11)

WB (47)

Flo (8)

ELISA (13)

ICC (3)

IF (2)

IP (6)

Peptide-ELISA (1)

Host

rabbit (47)

mouse (19)

rat (1)

Product Group

IHCPlus (1)

Isotype

IgG (21)

IgG1 (5)

IgG2a (2)

IgG2a,k (1)

IgG2b (3)

IgG2b,k (7)

IgG2c,k (2)

Clonality

monoclonal mc (20)

polyclonal pc (47)

Clone

3B4 (1)

5B10 (3)

BOR21 (1)

CB5.4 (1)

delta G9 (4)

dG9 (2)

MRQ-23 (1)

PRF1/2468 (1)

PRF1/2470 (2)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (2)

96-Well Strip Plate (22)

APC (3)

APC Conjugated (3)

Azide-free (2)

Biotin Conjugated (8)

BSA-free (2)

Concentrated (1)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (7)

HRP Conjugated (6)

PE Conjugated (4)

Ready-to-Use (1)

RPE Conjugated (1)

Unconjugated (32)

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Epitope

aa120-353 (8)

aa32-316 (8)

aa40-355 (8)

aa146-195 (4)

C-Terminus (1)

aa175-555 (1)

aa461-555 (1)

aa9-214 (1)

Publications

No (108)

Yes (1)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (3)

Plasma (19)

Serum (19)

Tissue Homogenates (8)

Tag

10His, N-terminus + Myc, C-terminus (1)

6His, N-terminus (3)

6His-SUMO, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His-GST, N-terminus (2)

His-T7 (1)

MBP, N-terminus + 6His, C-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (10)

Mouse (2)

Rat (2)

Vibrio vulnificus (1)

Source

293T Cells (2)

Baculovirus (1)

E. coli (8)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (1)

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PRF1 / Perforin Antibody (clone CB5.4) LS-C18632

(4.0) Rating

(1) Publication(s)

Antibody:

PRF1 / Perforin Rat anti-Mouse Monoclonal (CB5.4) Antibody

Reactivity:

Mouse

Applications:

ICC, IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µg/$508

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PRF1 / Perforin Antibody LS-C330792

Antibody:

PRF1 / Perforin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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PRF1 / Perforin Antibody (clone delta G9) LS-C134746

Antibody:

PRF1 / Perforin Mouse anti-Human Monoclonal (delta G9) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr

Format:

Unconjugated

Price:

100 µg/$446

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PRF1 / Perforin Antibody (aa461-555, clone 3B4) LS-C197980

Antibody:

PRF1 / Perforin Mouse anti-Human Monoclonal (aa461-555) (3B4) Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$423

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PRF1 / Perforin Antibody (clone 5B10) LS-C312144

Antibody:

PRF1 / Perforin Mouse anti-Human Monoclonal (5B10) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.1 ml/$348

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PRF1 / Perforin Antibody (clone 5B10, Ready-to-Use) LS-C348569

Antibody:

PRF1 / Perforin Mouse anti-Human Monoclonal (Ready-to-Use) (5B10) Antibody

Reactivity:

Human

Applications:

IHC-Fr, IHC-P

Format:

Unconjugated, Ready-to-Use

Price:

3 ml/$358

• Unconjugated
• Unconjugated, Ready-to-Use

• Unconjugated
• Unconjugated, Ready-to-Use

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Human PRF1 / Perforin (Sandwich ELISA) ELISA Kit - LS-F12308

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse PRF1 / Perforin (Sandwich ELISA) ELISA Kit - LS-F6493

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

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Human PRF1 / Perforin Protein (Recombinant 6His-SUMO, N-terminus) (aa22-555) - LS-G21075

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Molecular Weight:

75.1 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse PRF1 / Perforin (Sandwich ELISA) ELISA Kit - LS-F21422

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human PRF1 / Perforin (Sandwich ELISA) ELISA Kit - LS-F52456

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$703

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Human PRF1 / Perforin Protein (Recombinant 6His, N-terminus) (Pro22-Trp555) - LS-G26593

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

59.2 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Mouse PRF1 / Perforin Protein (Recombinant His-GST, N-terminus) (Val40-Lys355) - LS-G13648

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

67.2 kDa

Price:

10 µg/$299; 50 µg/$552; 100 µg/$882; 200 µg/$1,080; 1 mg/$2,261; 500 µg/$1,775; 5 mg/$3,851; 2 mg/$2,453

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PRF1 / Perforin Antibody (clone BOR21) LS-C107481

Antibody:

PRF1 / Perforin Mouse anti-Human Monoclonal (BOR21) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$442

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Human PRF1 / Perforin (Sandwich ELISA) ELISA Kit - LS-F4557

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

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PRF1 / Perforin Antibody (clone dG9) LS-C742191

Antibody:

PRF1 / Perforin Mouse anti-Human Monoclonal (dG9) Antibody

Reactivity:

Bovine, Human

Applications:

Flo, ICC, IHC-Fr, IHC-P, IP

Format:

Unconjugated

Price:

0.1 mg/$316

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PRF1 / Perforin Antibody LS-C743305

Antibody:

PRF1 / Perforin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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PRF1 / Perforin Antibody (aa120-353) LS-B15024

Antibody:

PRF1 / Perforin Rabbit anti-Rat Polyclonal (aa120-353) Antibody

Reactivity:

Rat

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Human PRF1 / Perforin (Sandwich ELISA) ELISA Kit - LS-F33262

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human PRF1 / Perforin Protein (Recombinant GST) (Full Length) - LS-G29882

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.48 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PRF1 / Perforin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77955

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.38 kDa

Price:

20 µg/$150

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PRF1 / Perforin Antibody LS-C285587

Antibody:

PRF1 / Perforin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PRF1 / Perforin Antibody (Biotin) LS-C370158

Antibody:

PRF1 / Perforin Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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PRF1 / Perforin Antibody (Biotin) LS-C38141

Antibody:

PRF1 / Perforin Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

Flo

Format:

Biotin Conjugated

Price:

100 µg/$763

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PRF1 / Perforin Antibody (aa9-214) LS-C185482

Antibody:

PRF1 / Perforin Rabbit anti-Human Polyclonal (aa9-214) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$450

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