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PLP1 / Myelin PLP

proteolipid protein 1

PLP1 / Myelin PLP is a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.

Gene Name: proteolipid protein 1
Synonyms: PLP1, HLD1, PMD, Myelin proteolipid protein, Proteolipid protein 1, SPG2, Lipophilin, MMPL, PLP, PLP/DM20
Target Sequences: NM_000533 NP_000524.3

Publications (1)

1
Transient immune activation without loss of intraepidermal innervation and associated Schwann cells in patients with complex regional pain syndrome. Beate Hartmannsberger, Sabrina Scriba, Carolina Guidolin, Juliane Becker, Katharina Mehling, Kathrin Doppler, Claudia Sommer, Heike L Rittner. Journal of neuroinflammation. 2024 January;21:23. [Full Text Article] [PubMed:38233858] [PMC:PMC10792943]

☰ Filters
Antibodies (33)
ELISA Kits (16)
Proteins (11)
Custom (4)
Over-Expression Lysate (6)
Primary (33)
Recombinant (5)
Sandwich (12)
PLP1 / Myelin PLP (60)
Human (31)
Mouse (13)
Rat (10)
Bat (2)
Bovine (10)
Chicken (2)
Chimpanzee (5)
Dog (6)
Gibbon (5)
Guinea pig (5)
Horse (5)
Mammal (10)
Monkey (6)
Orangutan (5)
Pig (6)
Porcine (1)
Rabbit (6)
Rainbow trout (4)
IHC (21)
IHC-Fr (2)
IHC-P (11)
WB (25)
Flo (1)
ELISA (9)
ICC (8)
IF (1)
Peptide-ELISA (1)
rabbit (18)
mouse (13)
chicken (2)
Product Group
IHCPlus (4)
IgG (15)
IgG2a (11)
IgG2a,k (1)
IgM (1)
IgY (1)
monoclonal mc (13)
polyclonal pc (20)
2D7 (1)
plpc1 (1)
96-Well Strip Plate (16)
APC Conjugated (1)
Biotin Conjugated (6)
FITC Conjugated (5)
HRP Conjugated (6)
PE Conjugated (2)
Preservative Free (1)
Unconjugated (13)
aa150-218 (4)
aa72-121 (4)
aa36-85 (3)
C-Terminus (2)
aa143-197 (2)
aa248-277 (1)
No (60)
Cell Culture Supernatants (1)
Cell Lysates (2)
Plasma (6)
Serum (6)
Tissue Homogenates (4)
10His, N-terminus (1)
GST, N-terminus (1)
GST-His, N-terminus (1)
His (2)
Myc-DDK (Flag) (6)
Human (6)
Rainbow trout (2)
293T Cells (3)
E. coli (3)
HEK 293 Cells (3)
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Purified (1)
PLP1 / Myelin PLP Antibody - Anti-PLP1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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PLP1 / Myelin PLP Mouse anti-Bovine Monoclonal (C-Terminus) (plpc1) Antibody
Bovine
Flo, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.05 mg/$485
PLP1 / Myelin PLP Antibody - Anti-PLP1 antibody IHC of human brain cerebellum, neuropil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
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PLP1 / Myelin PLP Mouse anti-Human Monoclonal (C-Terminus) Antibody
Mammal, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$485
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PLP1 / Myelin PLP Mouse anti-Human Monoclonal (APC) Antibody
Mammal, Human
ICC, IHC, WB
APC Conjugated
100 µl/$1,129
PLP1 / Myelin PLP Antibody - Anti-PLP1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PLP1 / Myelin PLP Rabbit anti-Human Polyclonal (aa36-85) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PLP1 / Myelin PLP Antibody - Anti-PLP1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PLP1 / Myelin PLP Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
PLP1 / Myelin PLP Antibody - Detection limit for recombinant GST tagged PLP1 is approximately 0.1 ng/ml as a capture antibody.
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PLP1 / Myelin PLP Mouse anti-Human Monoclonal (2D7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
PLP1 / Myelin PLP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
PLP1 / Myelin PLP Protein - Recombinant Proteolipid Protein 1, Myelin (PLP1) by SDS-PAGE
Select
E. coli
GST-His, N-terminus
16kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
PLP1 / Myelin PLP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
PLP1 / Myelin PLP Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus
35.5 kDa
100 µg/$1,801; 20 µg/$1,247
PLP1 / Myelin PLP Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at dilution of 1:100.
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PLP1 / Myelin PLP Rabbit anti-Human Polyclonal (aa143-197) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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PLP1 / Myelin PLP Rabbit anti-Human Polyclonal (aa143-197) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
PLP1 / Myelin PLP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$715
PLP1 / Myelin PLP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
PLP1 / Myelin PLP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PLP1 / Myelin PLP Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PLP1 / Myelin PLP Rabbit anti-Human Polyclonal (aa72-121) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PLP1 / Myelin PLP Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PLP1 / Myelin PLP Rabbit anti-Human Polyclonal (aa72-121) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
PLP1 / Myelin PLP Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PLP1 / Myelin PLP Rabbit anti-Human Polyclonal (aa72-121) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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PLP1 / Myelin PLP Chicken Polyclonal Antibody
Mouse, Human
ICC, IHC, WB
Unconjugated
1000 µl/$666
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PLP1 / Myelin PLP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PLP1 / Myelin PLP Antibody - Western blot analysis of extracts of various cell lines, using PLP1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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PLP1 / Myelin PLP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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PLP1 / Myelin PLP Rabbit anti-Rainbow trout Polyclonal (aa150-218) Antibody
Rainbow trout
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
PLP1 / Myelin PLP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$764
PLP1 / Myelin PLP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Select
PLP1 / Myelin PLP Chicken anti-Mouse Polyclonal Antibody
Mouse
ICC, IHC, WB
Unconjugated
100 µg/$924
Viewing 1-25 of 60 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).