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Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Gene Name: | profilin 2 |
Synonyms: | PFN2, D3S1319E, PFL, Profilin II, Profilin-2, Profilin 2 |
Target Sequences: | NM_002628 NP_002619.1 P35080 |
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