PDGF-BB

platelet-derived growth factor beta polypeptide

PDGF-BB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

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Proteins (34)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (6)

Recombinant (27)

Target

PDGF-BB (34)

Format

Animal-free (1)

Publications

No (34)

Tag

6His, C-terminus (2)

6His, N-terminus (4)

GST, N-terminus (1)

His (1)

His, N-Terminal (2)

His, N-terminus (1)

His,C-terminus (1)

His,N-terminus (1)

His-GST (2)

His-S (1)

His-T7 (1)

Myc-DDK (Flag) (4)

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Species

Human (19)

Mouse (10)

Rat (3)

Source

293T Cells (2)

E. coli (24)

HEK 293 Cells (5)

Wheat Germ Extract (1)

Yeast (2)

Purification

Purified (7)

Low Endotoxin Level

Low endotoxin level (16)

Biologically Active

Biologically active (12)

Animal-free

Animal-free (1)

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Mouse PDGF-BB Protein (Over-Expression Lysate 6His, N-terminus) (Ser82-Thr190) - LS-G26804

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

15 kDa

Price:

100 µg/$298

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Human PDGF-BB Protein (Recombinant 6His, N-terminus) - LS-G26392

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

12 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Mouse PDGF-BB Protein (Recombinant) - LS-G368

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

24.4 kDa

Price:

2 µg/$268; 10 µg/$349

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Human PDGF-BB Protein (Recombinant) - LS-G14

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

24.3 kDa

Price:

2 µg/$268; 10 µg/$349

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Human PDGF-BB Protein (Recombinant) - LS-G3672

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

2 µg/$281; 10 µg/$369

• Unmodified
• Animal-free

• Unmodified
• Animal-free

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Human PDGF-BB Protein (Recombinant His) - LS-G3222

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human PDGF-BB Protein (Recombinant) (Ser82-Thr190) - LS-G38731

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.42kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human PDGF-BB Protein (Recombinant GST, N-terminus) (aa82-190) - LS-G59545

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PDGF-BB Protein (Over-Expression Lysate His, N-Terminal) (Ser82-Thr190) - LS-G96897

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~12 kDa

Price:

100 µg/$298

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PDGF-BB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99804

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.28 kDa

Price:

100 µg/$494

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PDGF-BB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108475

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.3 kDa

Price:

100 µg/$494

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Human PDGF-BB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78115

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.3 kDa

Price:

20 µg/$150

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Human PDGF-BB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78111

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.28 kDa

Price:

20 µg/$150

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Human PDGF-BB Protein (Recombinant His, N-Terminal) - LS-G144230

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

24.9 kDa

Price:

50 µg/$419

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Human PDGF-BB Protein (Recombinant) - LS-G145652

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

24.8 kDa

Price:

10 µg/$364; 1 mg/$3,412

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Rat PDGF-BB Protein (Recombinant His, N-terminus) - LS-G146353

Source:

E. coli

Tag:

His, N-terminus

Molecular Weight:

12.2 kDa

Price:

20 µg/$270; 100 µg/$390

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Human PDGF-BB Protein (Recombinant) - LS-G131284

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~16 kDa

Price:

10 µg/$291; 500 µg/$1,090; 1 mg/$1,691

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Mouse PDGF-BB Protein (Recombinant 6His, C-terminus) - LS-G137876

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,654; 1 mg/$2,353

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Human PDGF-BB Protein (Recombinant) (Full Length) - LS-G136925

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.42 kDa

Price:

50 µg/$698; 10 µg/$356; 1 mg/$2,837; 500 µg/$1,987

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Mouse PDGF-BB Protein (Recombinant) - LS-G137637

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 109 amino acid recombinant protein has a predicted molecular mass of approximately 12.2 kD. The DTT-reduced and non-reduced protein migrate at approximately 14 and 38 kD respectively by SDS-PAGE. The predicted N-terminal amino acid is Ser.

Price:

10 µg/$306; 25 µg/$383; 100 µg/$900

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Human PDGF-BB Protein (Recombinant) - LS-G137638

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 109 amino acid recombinant protein has a predicted molecular mass of 12,294 Da. The DTT-reduced and the non-reduced protein migrate at approximately 13 and 37 KDa by SDS-PAGE respectively. The N-terminal amino acid is Serine.

Price:

10 µg/$306; 25 µg/$383; 100 µg/$900; 500 µg/$1,828

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Human PDGF-BB Protein (Recombinant His,N-terminus) (Ser82-Thr190) - LS-G138537

Source:

Yeast

Tag:

His,N-terminus

Molecular Weight:

14.3 kDa

Price:

50 µg/$793; 1 mg/$3,773

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Mouse PDGF-BB Protein (Recombinant 6His, C-terminus) (Full Length) - LS-G137271

Source:

E. coli

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

13.4 kDa

Price:

50 µg/$516; 10 µg/$313; 1 mg/$3,095; 500 µg/$2,115

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Mouse PDGF-BB Protein (Recombinant His,C-terminus) (Ser82-Thr190) - LS-G139884

Source:

E. coli

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

13.4 kDa

Price:

10 µg/$288; 50 µg/$436

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Human PDGF-BB Protein (Recombinant) (Ser82-Thr190) - LS-G140336

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.4 kDa

Price:

10 µg/$317; 50 µg/$524

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