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PD-L2 / PDCD1LG2 / CD273

programmed cell death 1 ligand 2

Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Gene Name: programmed cell death 1 ligand 2
Synonyms: PDCD1LG2, B7 dendritic cell molecule, B7-DC, B7DC, BA574F11.2, CD273, Btdc, CD273 antigen, PD-L2, PDCD1 ligand 2, PD-1-ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, PD-1 ligand 2, PDCD1L2, PDL2
Target Sequences: NM_025239 NP_079515.2 Q9BQ51

Publications (1)

1
EML4-ALK enhances programmed cell death-ligand 1 expression in pulmonary adenocarcinoma via hypoxia-inducible factor (HIF)-1a and STAT3. Koh J, Jang JY, Keam B, Kim S, Kim MY, Go H, Kim TM, Kim DW, Kim CW, Jeon YK, Chung DH. Oncoimmunology. 2016 5:e1108514. (Flo; Human) [Full Text Article] [PubMed:27141364]

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Antibodies (119)
Primary (119)
PD-L2 / PDCD1LG2 / CD273 (119)
Human (87)
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No (119)
PD-L2 / PDCD1LG2 / CD273 Antibody - Human Brain, Cortex, White Matter: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PD-L2 / PDCD1LG2 / CD273 Rabbit anti-Mouse Polyclonal (aa36-219) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
50 µl/$460
PD-L2 / PDCD1LG2 / CD273 Antibody - Immunohistochemistry of PDL-2 in mouse brain tissue with PDL-2 antibody at 2.5 ug/ml.
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PD-L2 / PDCD1LG2 / CD273 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
PD-L2 / PDCD1LG2 / CD273 Antibody - Surface staining of B7-DC transfected cells with anti-mouse B7-DC (TY25) PE. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.
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PD-L2 / PDCD1LG2 / CD273 Rat anti-Mouse Monoclonal (TY25) Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
50 µg/$285; 100 µg/$355; 500 µg/$457
PD-L2 / PDCD1LG2 / CD273 Antibody - Staining of non-transfected cells with 0.25 ug PE Rat IgG2a isotype control (open histogram) or 0.06 ug PE anti-mouse B7-DC (TY25, colored histogram). Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PD-L2 / PDCD1LG2 / CD273 Rat anti-Mouse Monoclonal (PE) (TY25) Antibody
Mouse
Flo
PE Conjugated
50 µg/$307; 100 µg/$345; 200 µg/$450
PD-L2 / PDCD1LG2 / CD273 Antibody - Flow cytometry of PD-L2 antibody
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PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (ANC8D12) Antibody
Human
Block, ELISA, Flo
Unconjugated
100 µg/$446
PD-L2 / PDCD1LG2 / CD273 Antibody - Flow cytometry of PD-L2 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (FITC) (ANC8D12) Antibody
Human
Block, ELISA, Flo
FITC Conjugated
120 Tests/$536
PD-L2 / PDCD1LG2 / CD273 Antibody - IHC of paraffin-embedded Human tonsil using anti-PDCD1LG2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (OTI8G8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
PD-L2 / PDCD1LG2 / CD273 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) at 10 µg/ml.
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Cancer Pathology
Cancer
PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (10H6) Antibody
Human
ELISA, Flo, ICC, IF, IHC-P, WB
Unconjugated
0.1 mg/$485
PD-L2 / PDCD1LG2 / CD273 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) at 10 µg/ml.
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PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (8C12) Antibody
Human
ELISA, Flo, ICC, IF, IHC-P, WB
Unconjugated
0.05 mg/$460
PD-L2 / PDCD1LG2 / CD273 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) at 10 µg/ml.
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PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (4E10) Antibody
Human
ELISA, Flo, ICC, IF, IHC-P, WB
Unconjugated
0.05 mg/$460
PD-L2 / PDCD1LG2 / CD273 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) at 10 µg/ml.
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PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (7C7) Antibody
Human
ELISA, Flo, ICC, IF, IHC-P, WB
Unconjugated
0.05 mg/$460
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PD-L2 / PDCD1LG2 / CD273 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$729
PD-L2 / PDCD1LG2 / CD273 Antibody - Human Lymph Node: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
PD-L2 / PDCD1LG2 / CD273 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
PD-L2 / PDCD1LG2 / CD273 Antibody - Immunohistochemistry of PD-L2 in human tonsil tissue with PD-L2 antibody at 2 ug/mL.
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PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (7C1) Antibody
Human
ELISA, Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$502
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PD-L2 / PDCD1LG2 / CD273 Rat anti-Mouse Monoclonal (TY25) Antibody
Mouse
Flo, IHC, IHC-Fr, IHC-P, IP
Unconjugated
250 µg/$732
PD-L2 / PDCD1LG2 / CD273 Antibody - Flow cytometry of PD-L2 antibody
Select
PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (ANC8D12) Antibody
Human
Block, ELISA, Flo
Unconjugated
100 µg/$446
PD-L2 / PDCD1LG2 / CD273 Antibody - Surface staining of CD273 on monocyte-derived dendritic cells with anti-CD273 (24F.10C12) PE.
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PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (PE) (24F.10C12) Antibody
Human
Flo, Func, IHC
PE Conjugated
100 Tests/$365
PD-L2 / PDCD1LG2 / CD273 Antibody - Human monocyte-derived dendritic cells were stained with anti-human CD273 (clone 24F.10C12) Purified (filled histogram) or mouse IgG2a, kappa Purified isotype control (open histogram), followed by biotinylated mouse IgG and SAV-PE.
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PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (24F.10C12) Antibody
Human, Baboon, African green monkey, Cynomolgus monkey, Rhesus monkey
Flo, Func, IHC-Fr
Unconjugated
100 µg/$283
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PD-L2 / PDCD1LG2 / CD273 Rabbit anti-Human Polyclonal Antibody
Human
Flo
Unconjugated
100 µl/$412
PD-L2 / PDCD1LG2 / CD273 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-PDCD1LG2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 2.5 min. (1:500)
Select
PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (UMAB223) Antibody
Human
Flo, IHC, PMA, WB
Unconjugated
100 µl/$493
PD-L2 / PDCD1LG2 / CD273 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-PDCD1LG2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 2.5 min. (1:500)
Select
PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (Carrier-free) (UMAB223) Antibody
Human
Flo, IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
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PD-L2 / PDCD1LG2 / CD273 Rabbit anti-Mouse Monoclonal (Preservative Free) (208) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
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PD-L2 / PDCD1LG2 / CD273 Goat anti-Mouse Polyclonal Antibody
Mouse
ELISA, Flo, Func, IHC, WB
Unconjugated
100 µg/$930
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PD-L2 / PDCD1LG2 / CD273 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
PD-L2 / PDCD1LG2 / CD273 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PDCD1LG2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150) .
Select
PD-L2 / PDCD1LG2 / CD273 Mouse anti-Human Monoclonal (OTI5E5) Antibody
Human
Flo, IHC, WB
Unconjugated
100 µl/$434
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).