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NTRK3 / TRKC
neurotrophic tyrosine kinase, receptor, type 3
NTRK3 / TRKC is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | neurotrophic tyrosine kinase, receptor, type 3 |
| Family/Subfamily: | Protein Kinase , Trk/Ror |
| Synonyms: | NTRK3, ETV6-NTRK3 fusion, gp145-TrkC, Neurotrophin 3 receptor, TRKC, TrkC tyrosine kinase, NT-3 growth factor receptor, NT3 growth factor receptor, Tyrosine kinase receptor C, Pan Trk, gp145(trkC), Trk-C |
| Target Sequences: | NM_002530 NP_002521.2 Q16288 |
Publications (1)
1
Differential Clinical Significance of Neurotrophin-3 Expression according to MYCN Amplification and TrkC Expression in Neuroblastoma. Seo E#, Kim JS#, Ma YE, Cho HW, Ju HY, Lee SH, Lee JW, Yoo KH, Sung KW, Koo HH. Journal of Korean Medical Science. 2019 October;34:e254. [Full Text Article]
[PubMed:31602824]
[PMC:PMC6786962]
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NTRK3 / TRKC
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(75)
Neuroscience
NTRK3 / TRKC Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
NTRK3 / TRKC Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
ELISA, IP, WB
Unconjugated
100 µg/$567
NTRK3 / TRKC Goat anti-Human Polyclonal (aa32-428) (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$848
NTRK3 / TRKC Mouse anti-Human Monoclonal (OTI4E10) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
NTRK3 / TRKC Mouse anti-Human Monoclonal (Carrier-free) (OTI4E10) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
NTRK3 / TRKC Rabbit anti-Human Polyclonal (aa31-61) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
NTRK3 / TRKC Rabbit anti-Human Polyclonal (pTyr820) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
500 µg/$393
NTRK3 / TRKC Rabbit anti-Rat Polyclonal (Extracellular Domain) Antibody
Mouse, Rat, Human
IHC
Unconjugated
500 µg/$393
NTRK3 / TRKC Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
NTRK3 / TRKC Sheep anti-Human Polyclonal (pTyr820) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
500 µg/$393
NTRK3 / TRKC Mouse anti-Human Monoclonal (OTI24B3) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
NTRK3 / TRKC Mouse anti-Human Monoclonal (Carrier-free) (OTI24B3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
NTRK3 / TRKC Mouse anti-Human Monoclonal (OTI2B8) Antibody
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
NTRK3 / TRKC Mouse anti-Human Monoclonal (Carrier-free) (OTI2B8) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
NTRK3 / TRKC Rabbit anti-Human Polyclonal (aa300-400) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P
Unconjugated
0.1 ml/$386
NTRK3 / TRKC Rabbit anti-Mouse Polyclonal (aa161-188) Antibody
Mouse
ELISA, IHC, WB
Unconjugated
200 µl/$734
NTRK3 / TRKC Rabbit anti-Human Polyclonal (pTyr516) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
NTRK3 / TRKC Mouse anti-Human Monoclonal (7H6) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$467
NTRK3 / TRKC Rabbit anti-Human Polyclonal (aa40-300) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
NTRK3 / TRKC Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
NTRK3 / TRKC Rabbit anti-Human Polyclonal (aa167-182) Antibody
Dog, Sheep, Bovine, Pig, Bat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
NTRK3 / TRKC Rabbit anti-Human Polyclonal (aa31-61) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
NTRK3 / TRKC Rabbit anti-Human Polyclonal (aa31-61) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
NTRK3 / TRKC Mouse anti-Human Monoclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
NTRK3 / TRKC Rabbit anti-Human Polyclonal (aa172-186) Antibody
Mouse, Sheep, Bovine, Rat, Human
IHC, WB
Unconjugated
10 µg/$318; 100 µg/$470
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