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NTN1 / Netrin 1
netrin 1
Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
| Gene Name: | netrin 1 |
| Synonyms: | NTN1, Netrin 1, Netrin 1, mouse, homolog of, Netrin-1, NTN1L |
| Target Sequences: | NM_004822 NP_004813.2 O95631 |
Publications (2)
1
Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities. Seiko Ikezu , Hana Yeh , Jean-Christophe Delpech , Maya E Woodbury , Alicia A Van Enoo, Zhi Ruan, Sudhir Sivakumaran, Yang You, Carl Holland, Teresa Guillamon-Vivancos, Asuka Yoshii-Kitahara, Mina B Botros, Charlotte Madore, Pin-Hao Chao, Ankita Desani, Solaiappan Manimaran, Srinidhi Venkatesan Kalavai, W Evan Johnson, Oleg Butovsky, Maria Medalla, Jennifer I Luebke, Tsuneya Ikezu. Molecular psychiatry. 2020 February; [Full Text Article]
[PubMed:32071385]
[PMC:PMC7431382]
2
PMN-derived netrin-1 attenuates cardiac ischemia-reperfusion injury via myeloid ADORA2B signaling. Jiwen Li, Catharina Conrad, Tingting W Mills, Nathaniel K Berg, Boyun Kim, Wei Ruan, Jae W Lee, Xu Zhang, Xiaoyi Yuan, Holger K Eltzschig. The Journal of experimental medicine. 2021 June;218:e20210008. [Full Text Article]
[PubMed:33891683]
[PMC:PMC8077173]
Related Antibodies: LS-C743016.
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Products
Proteins
(6)
Type
Recombinant
(6)
Target
NTN1 / Netrin 1
(6)
Publications
No
(6)
Tag
DDK (Flag)
(1)
GST, N-terminus
(1)
His, N-Terminal
(1)
His-GST
(1)
His-GST, N-terminus
(1)
Human IgG1 Fc
(1)
Species
Human
(4)
Mouse
(1)
Rat
(1)
Source
E. coli
(3)
HEK 293 Cells
(2)
Wheat Germ Extract
(1)
Purification
Purified
(1)
Low Endotoxin Level
Low endotoxin level
(2)
E. coli
His, N-Terminal
55.5kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Wheat Germ Extract
GST, N-terminus
2 µg/$439
E. coli
His-GST, N-terminus
58kDa
10 µg/$288; 50 µg/$487; 200 µg/$972; 100 µg/$780; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
HEK 293 Cells
DDK (Flag)
Less than 0.01 EU/µg protein (determined by LAL method).
~80kDa (SDS-PAGE)
10 µg/$386
HEK 293 Cells
Human IgG1 Fc
Less than 0.1 EU/µg protein (determined by LAL method).
~90kDa (SDS-PAGE)
10 µg/$414
E. coli
His-GST
55.5 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
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