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NT5E / eNT / CD73

5'-nucleotidase, ecto (CD73)

NT5E / eNT / CD73 is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: 5'-nucleotidase, ecto (CD73)
Synonyms: NT5E, 5-nucleotidase, ecto (CD73), 5'-nucleotidase, 5 nucleotidase (CD73), 5-NT, 5-nucleotidase, 5'-nucleotidase, ecto (CD73), CD73, CD73 antigen, E5NT, Ecto-5-nucleotidase, ENT, EN, NT, Purine 5-Prime-Nucleotidase, NT5, NTE
Target Sequences: NM_002526 NP_002517.1 P21589

Publications (6)

1
Hypoxia-inducible factor-1-dependent protection from intestinal ischemia/reperfusion injury involves ecto-5'-nucleotidase (CD73) and the A2B adenosine receptor. Hart ML, Grenz A, Gorzolla IC, Schittenhelm J, Dalton JH, Eltzschig HK. Journal of immunology (Baltimore, Md. : 1950). 2011 186:4367-74. [PubMed:21357264] Related Antibodies: LS-B3428.
2
Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF-a-Induced Injury In Vitro. Cinti A, De Giorgi M, Chisci E, Arena C, Galimberti G, Farina L, Bugarin C, Rivolta I, Gaipa G, Smolenski RT, Cerrito MG, Lavitrano M, Giovannoni R. PloS one. 2015 10:e0141933. (WB; Human) [Full Text Article] [PubMed:26513260] [PMC:PMC4626094]
3
Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia. Iriyama T, Sun K, Parchim NF, Li J, Zhao C, Song A, Hart LA, Blackwell SC, Sibai BM, Chan LN, Chan TS, Hicks MJ, Blackburn MR, Kellems RE, Xia Y. Circulation. 2015 131:730-41. (IHC; Mouse) [Full Text Article] [PubMed:25538227] [PMC:PMC4751998] Related Antibodies: LS-B2943.
4
Co-expression of functional human Heme Oxygenase 1, Ecto-5'-Nucleotidase and ecto-nucleoside triphosphate diphosphohydrolase-1 by self-cleaving" 2A peptide system.". Marco De Giorgi, Alessandro Cinti, Iwona Pelikant-Malecka, Elisa Chisci, Marialuisa Lavitrano, Roberto Giovannoni, Ryszard T Smolenski. Plasmid. 2015 May;79:22-9. [Full Text Article] [PubMed:25779031]
5
CD117 expression in fibroblasts-like stromal cells indicates unfavorable clinical outcomes in ovarian carcinoma patients. Ruixia Huang, Dan Wu, Yuan Yuan, Xiaoran Li, Ruth Holm, Claes G Trope, Jahn M Nesland, Zhenhe Suo. PloS one. 2014 November;9:e112209. [Full Text Article] [PubMed:25380303] [PMC:PMC4224427]
6
Hyperosmolar expansion medium improves nucleus pulposus cell phenotype. Lisanne T Laagland, Frances C Bach, Laura B Creemers, Christine L Le Maitre, Deepani W Poramba-Liyanage, Marianna A Tryfonidou. JOR spine. 2022 September;5:e1219. [Full Text Article] [PubMed:36203869] [PMC:PMC9520765] Related Antibodies: LS-B8284.
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Antibodies (124)
Primary (124)
NT5E / eNT / CD73 (124)
Human (82)
Mouse (38)
Rat (30)
Bat (3)
Bovine (8)
Chimpanzee (3)
Cow (7)
Cynomolgus (2)
Dog (3)
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Rabbit (3)
IHC (39)
IHC-Fr (1)
IHC-P (14)
WB (94)
Flo (27)
ELISA (37)
Func (1)
ICC (2)
IF (4)
IHC-IF (1)
IP (5)
Peptide-ELISA (1)
SDS-PAGE (1)
rabbit (73)
mouse (40)
rat (10)
sheep (1)
Product Group
IHCPlus (7)
IgG (33)
IgG1 (15)
IgG1,k (10)
IgG2a,k (9)
IgG2b (2)
IgG2b,k (3)
monoclonal mc (49)
polyclonal pc (73)
recombinant monoclonal rmc (2)
10f1 (2)
1D7 (2)
2B6 (1)
45M4F9 (1)
4C4-2B5 (1)
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4G6B10 (1)
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OTI1G2 (2)
TY/23 (9)
YDBYT 208.3 (1)
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Unconjugated (55)
aa29-550 (24)
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aa1-30 (7)
aa520-550 (7)
aa433-482 (4)
aa1-511 (2)
aa119-232 (2)
431-480 aa, Internal (1)
Internal (1)
aa169-324 (1)
aa27-252 (1)
aa29-549 (1)
aa30-250 (1)
No (121)
Yes (3)
NT5E / eNT / CD73 Antibody - Anti-NT5E / CD73 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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NT5E / eNT / CD73 Mouse anti-Human Monoclonal (aa27-252) (2B6) Antibody
Human
ELISA, IF, IHC, IHC-P, SDS-PAGE, WB
Unconjugated
50 µl/$460
NT5E / eNT / CD73 Antibody - Anti-CD73 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NT5E / eNT / CD73 Rabbit anti-Human Polyclonal (aa433-482) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
NT5E / eNT / CD73 Antibody - Anti-CD73 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NT5E / eNT / CD73 Rabbit anti-Human Polyclonal (aa433-482) (FITC) Antibody
Rabbit, Mouse, Dog, Rat, Bat, Gibbon, Chimpanzee, Orangutan, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
NT5E / eNT / CD73 Antibody - Anti-NT5E / CD73 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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NT5E / eNT / CD73 Rabbit anti-Human Polyclonal (aa520-550) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
NT5E / eNT / CD73 Antibody - Anti-NT5E / CD73 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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NT5E / eNT / CD73 Mouse anti-Human Monoclonal (1D7) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$460
NT5E / eNT / CD73 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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NT5E / eNT / CD73 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
NT5E / eNT / CD73 Antibody - Flow cytometric detection of human CD73 on Huvec (mAb 4G4). Black, red and blue line represents cells only, isotype control and 4G4 (4 ug/ml, respectively).
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NT5E / eNT / CD73 Mouse anti-Human Monoclonal (4G4) Antibody
Human
Flo, Func, IF, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$589
NT5E / eNT / CD73 Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using NT5E Polyclonal Antibody at dilution of 1:40.
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NT5E / eNT / CD73 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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NT5E / eNT / CD73 Mouse anti-Human Monoclonal (10f1) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$468
NT5E / eNT / CD73 Antibody - CD73 (NT5E) Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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NT5E / eNT / CD73 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
NT5E / eNT / CD73 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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NT5E / eNT / CD73 Mouse anti-Human Monoclonal (aa30-250) (4G6B10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$485
NT5E / eNT / CD73 Antibody - Western blot of recombinant NT5E / eNT / CD73.
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NT5E / eNT / CD73 Mouse anti-Rat Monoclonal (aa29-550) (FITC) Antibody
Rat
WB
FITC Conjugated
100 µl/$360; 200 µl/$425; 500 µl/$660; 1 ml/$818; 2 ml/$1,059; 5 ml/$1,872
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NT5E / eNT / CD73 Sheep anti-Mouse Polyclonal (aa29-549) Antibody
Mouse
ELISA, Flo, WB
Unconjugated
100 µg/$962
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NT5E / eNT / CD73 Rabbit anti-Human Polyclonal (aa520-550) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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NT5E / eNT / CD73 Rabbit anti-Human Polyclonal (aa520-550) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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NT5E / eNT / CD73 Rabbit anti-Human Polyclonal (aa520-550) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
NT5E / eNT / CD73 Rabbit anti-Human Polyclonal (aa520-550) (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
NT5E / eNT / CD73 Antibody - Human Thyroid, Capillaries: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
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NT5E / eNT / CD73 Mouse anti-Human Monoclonal (aa169-324) (Azide-free) (45M4F9) Antibody
Human
IHC, IHC-P, WB
Unconjugated, Azide-free
0.1 mg/$460
NT5E / eNT / CD73 Antibody - Western blot of recombinant NT5E / eNT / CD73.
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NT5E / eNT / CD73 Rabbit anti-Cow Polyclonal (aa48-527) Antibody
Bovine, Human
ICC, IP, WB
Unconjugated
100 µl/$322; 200 µl/$370; 500 µl/$529; 1 ml/$614; 2 ml/$846; 5 ml/$1,393
NT5E / eNT / CD73 Antibody - Western blot of recombinant NT5E / eNT / CD73.
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NT5E / eNT / CD73 Rabbit anti-Cow Polyclonal (aa48-527) (FITC) Antibody
Bovine, Cow, Human
WB
FITC Conjugated
100 µl/$367; 200 µl/$433; 500 µl/$686; 1 ml/$846; 2 ml/$1,092; 5 ml/$1,951
NT5E / eNT / CD73 Antibody - Western blot of recombinant NT5E / eNT / CD73.
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NT5E / eNT / CD73 Rabbit anti-Cow Polyclonal (aa48-527) (PE) Antibody
Bovine, Cow, Human
WB
PE Conjugated
100 µl/$434; 200 µl/$529; 500 µl/$938; 1 ml/$1,108; 2 ml/$1,487; 5 ml/$2,787
NT5E / eNT / CD73 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using NT5E Polyclonal Antibody at dilution of 1:50.
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NT5E / eNT / CD73 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
NT5E / eNT / CD73 Antibody - Western blot of recombinant NT5E / eNT / CD73.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
NT5E / eNT / CD73 Rabbit anti-Mouse Polyclonal (aa29-550) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
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NT5E / eNT / CD73 Rat anti-Mouse Monoclonal (FITC) (TY/23) Antibody
Mouse
Flo
FITC Conjugated
50 Tests/$233; 100 Tests/$248; 200 Tests/$268
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NT5E / eNT / CD73 Mouse anti-Human Monoclonal (aa1-511) (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$811
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).