NR1A2 / THRB

thyroid hormone receptor, beta

Thyroid hormone receptor beta (TR beta), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect cholesterol metabolism, hearing, cone development in the eye, and hypothalamopituitary-thyroid axis function. Mice lacking the TR beta locus exhibit elevated thyroid hormone levels, profound hearing loss, impaired weight gain, abnormal bone development, and loss of thyroid-hormone induced activation of cholesterol 7 alpha-hydroxylase (CYP7A). Mutation in the ligand-binding domain of TR beta has been linked to the genetic disorder Resistance to Thyroid Hormone (RTH), and possibly to human cone disorders. Congenital thyroid disorders that impair hearing and result in profound deafness are common in geographic areas with a prevalence of iodine deficiency. Two human TR beta protein isoforms have been identified: TR beta1 (461 aa), TR beta2 (476 aa). Two additional protein isoforms, TR beta3 (390 aa), and a non-DNA binding TR deltabeta3 (288 aa), have been documented in rat.

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Products

Antibodies (53)

Type

Primary (53)

Target

NR1A2 / THRB (53)

Reactivity

Human (45)

Mouse (26)

Rat (26)

Bat (3)

Bovine (3)

Chimpanzee (12)

Dog (7)

Gibbon (12)

Guinea pig (6)

Hamster (1)

Horse (7)

Monkey (13)

Pig (9)

Rabbit (7)

Sheep (3)

Zebrafish (4)

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Application

IHC (18)

IHC-P (11)

WB (53)

ELISA (9)

ICC (1)

IF (4)

IP (1)

Peptide-ELISA (6)

Host

rabbit (51)

goat (2)

Product Group

IHCPlus (1)

Isotype

IgG (23)

Clonality

polyclonal pc (53)

Format

APC (1)

APC Conjugated (1)

Biotin Conjugated (8)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (8)

HRP Conjugated (8)

PE Conjugated (1)

Unconjugated (25)

Epitope

N-Terminus (10)

aa239-457 (8)

C-Terminus (4)

aa1-461 (4)

aa37-86 (4)

aa53-102 (4)

aa71-120 (4)

pSer142 (2)

30-110 aa, N-terminal (1)

90-170 aa (1)

Leu37 (1)

aa11-60 (1)

aa183-199 (1)

aa216-227 (1)

aa378-427 (1)

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Publications

No (53)

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NR1A2 / THRB Antibody (aa11-60) LS-C118594

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (aa11-60) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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NR1A2 / THRB Antibody LS-C109507

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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NR1A2 / THRB Antibody LS-C800547

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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NR1A2 / THRB Antibody (aa378-427) LS-C200784

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (aa378-427) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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NR1A2 / THRB Antibody (Leu37) LS-C176246

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (Leu37) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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NR1A2 / THRB Antibody LS-C416128

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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NR1A2 / THRB Antibody (aa1-461) LS-C370425

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (aa1-461) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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NR1A2 / THRB Antibody (aa1-461, HRP) LS-C370431

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (aa1-461) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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NR1A2 / THRB Antibody (aa1-461, Biotin) LS-C370441

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (aa1-461) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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NR1A2 / THRB Antibody (aa1-461, FITC) LS-C370437

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (aa1-461) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

NR1A2 / THRB Antibody (aa37-86) LS-B1005

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (aa37-86) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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NR1A2 / THRB Antibody (aa37-86, HRP) LS-C432757

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (aa37-86) (HRP) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

NR1A2 / THRB Antibody (aa37-86, Biotin) LS-C432755

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (aa37-86) (Biotin) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

NR1A2 / THRB Antibody (aa37-86, FITC) LS-C432756

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (aa37-86) (FITC) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

NR1A2 / THRB Antibody (N-Terminus) LS-C60141

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$567

Select

NR1A2 / THRB Antibody (30-110 aa, N-terminal) LS-C386525

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

NR1A2 / THRB Antibody LS-C826041

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

NR1A2 / THRB Antibody LS-C331560

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

NR1A2 / THRB Antibody (N-Terminus) LS-C352939

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351

Select

NR1A2 / THRB Antibody LS-C833591

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

NR1A2 / THRB Antibody (90-170 aa) LS-C381086

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (90-170 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

NR1A2 / THRB Antibody (phospho-Ser142) LS-C825638

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (pSer142) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

NR1A2 / THRB Antibody (phospho-Ser142) LS-C199678

Antibody:

NR1A2 / THRB Rabbit anti-Human Polyclonal (pSer142) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

NR1A2 / THRB Antibody (aa216-227) LS-C55587

Antibody:

NR1A2 / THRB Goat anti-Human Polyclonal (aa216-227) Antibody

Reactivity:

Rabbit, Mouse, Dog, Rat, Hamster, Horse, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$493

Select

NR1A2 / THRB Antibody (N-Terminus) LS-C116031

Antibody:

NR1A2 / THRB Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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