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Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Gene Name: | Natriuretic Peptide A |
Synonyms: | NPPA, ANF, ANP, Atriopeptin, ATFB6, Atrial natriuretic factor, CDD-ANF, Cardionatrin, Natriuretic peptides A, Prepronatriodilatin, Natriuretic peptide A, PND, Natriuretic peptide precursor A |
Target Sequences: | NM_006172 NP_006163.1 P01160 |
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