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NOS1 / nNOS
nitric oxide synthase 1 (neuronal)
NOS1 / nNOS belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.
| Gene Name: | nitric oxide synthase 1 (neuronal) |
| Synonyms: | NOS1, BNOS, Constitutive NOS, IHPS1, NNOS, NC-NOS, Nitric oxide synthase, brain, N-NOS, Neuronal NOS, NOS, NOS type I, Nos, type i |
| Target Sequences: | NM_000620 NP_000611.1 P29475 |
Publications (4)
1
Senescent Cells Impair Erectile Function through Induction of Endothelial Dysfunction and Nerve Injury in Mice. Nishimatsu H, Suzuki E, Saito Y, Niimi A, Nomiya A, Fukuhara H, Kume H, Homma Y. PloS one. 2015 10:e0124129. (WB; Rat)
[Full Text Article]
[PubMed:25894557]
[PMC:PMC4404101]
2
Neuromedin B Restores Erectile Function by Protecting the Cavernous Body and the Nitrergic Nerves from Injury in a Diabetic Rat Model. Nishimatsu H, Suzuki E, Saito Y, Niimi A, Nomiya A, Yamada D, Homma Y. PloS one. 2015 10:e0133874. (ICC, WB; Human, Rat)
[Full Text Article]
[PubMed:26207818]
[PMC:PMC4514746]
3
PPARa induced NOS1 phosphorylation via PI3K/Akt in guinea pig antral mucous cells: NO-enhancement in Ca(2+)-regulated exocytosis. Tanaka S, Hosogi S, Sawabe Y, Shimamoto C, Matsumura H, Inui T, Marunaka Y, Nakahari T. Biomedical research (Tokyo, Japan). 2016 37:167-78. (WB; Human)
[Full Text Article]
[PubMed:27356604]
Related Antibodies: LS-B3272.
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NOS1 / nNOS
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Neuroscience
NOS1 / nNOS Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Guinea pig, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$495
Neuroscience
NOS1 / nNOS Rabbit anti-Human Polyclonal (aa1422-1433) Antibody
Rabbit, Mouse, Dog, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$460
NOS1 / nNOS Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$485
NOS1 / nNOS Rabbit anti-Human Polyclonal (aa818-867) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Neuroscience
NOS1 / nNOS Goat anti-Human Polyclonal (aa1457-1468) Antibody
Rabbit, Mouse, Dog, Horse, Bat, Human, Monkey
IF, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
NOS1 / nNOS Rabbit anti-Human Polyclonal (pSer1417) Antibody
Rat, Human
WB
Unconjugated
100 µg/$872
NOS1 / nNOS Sheep anti-Rat Polyclonal (aa1409-1429) Antibody
Rat
IHC, WB
Unconjugated
100 µl/$826
NOS1 / nNOS Rabbit anti-Human Polyclonal (pSer852) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NOS1 / nNOS Rabbit anti-Human Polyclonal (pSer852) Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
NOS1 / nNOS Mouse anti-Rat Monoclonal (N-Terminus) Antibody
Rat
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$786
NOS1 / nNOS Mouse anti-Rat Monoclonal (Biotin) Antibody
Mouse, Rat, Human
ELISA, IHC, IP, WB
Biotin Conjugated
100 µl/$1,017
NOS1 / nNOS Mouse anti-Rat Monoclonal (FITC) Antibody
Mouse, Rat, Human
ELISA, IHC, IP, WB
FITC Conjugated
100 µl/$1,017
NOS1 / nNOS Mouse anti-Rat Monoclonal (APC) Antibody
Mouse, Rat, Human
ELISA, IHC, IP, WB
APC Conjugated
100 µl/$1,017
NOS1 / nNOS Rabbit anti-Human Polyclonal (aa1418-1434) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$380
NOS1 / nNOS Rabbit anti-Human Polyclonal (pSer852) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
NOS1 / nNOS Rabbit anti-Human Polyclonal (aa724-739) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$957
NOS1 / nNOS Rabbit anti-Human Polyclonal (790-870 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
NOS1 / nNOS Rabbit anti-Human Polyclonal (pSer852) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
NOS1 / nNOS Rabbit anti-Human Polyclonal (790-870 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
NOS1 / nNOS Rabbit anti-Human Polyclonal Antibody
Chicken, Mouse, Rat, Human
ELISA, ICC, IF, WB
Unconjugated
100 µg/$597
NOS1 / nNOS Rabbit anti-Human Polyclonal (aa1199-1399) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217
NOS1 / nNOS Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
NOS1 / nNOS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
NOS1 / nNOS Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$717
NOS1 / nNOS Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
100 µl/$587
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