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NGF

nerve growth factor (beta polypeptide)

This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.

Gene Name: nerve growth factor (beta polypeptide)
Family/Subfamily: NGF Beta , not assigned-NGF Beta
Synonyms: NGF, Beta-nerve growth factor, ProNGF, Beta-NGF, HSAN5, NGFB
Target Sequences: NM_002506 NP_002497.2 P01138

Publications (4)

1
Isorhynchophylline exerts antidepressant-like effects in mice via modulating neuroinflammation and neurotrophins: involvement of the PI3K/Akt/GSK-3ß signaling pathway. Xian YF, Ip SP, Li HQ, Qu C, Su ZR, Chen JN, Lin ZX. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 September;33:10393-10408. [Full Text Article] [PubMed:31233346]
2
Shp2-mediated MAPK pathway regulates ?Np63 in epithelium to promote corneal innervation and homeostasis. Yuka Okada, Yujin Zhang, Lingling Zhang, Lung-Kun Yeh, Yen-Chiao Wang, Shizuya Saika, Chia-Yang Liu. Laboratory investigation; a journal of technical methods and pathology. 2020 Apr;100:630-642. [Full Text Article] [PubMed:31653968] [PMC:PMC7102931] Related Antibodies: LS-C171793.
3
Targeted screening of inflammatory mediators in spontaneous degenerative disc disease in dogs reveals an upregulation of the tumor necrosis superfamily. Thomas Bitterli, David Schmid, Ladina Ettinger, Olga Krupkova, Frances C Bach, Marianna A Tryfonidou, Björn P Meij, Antonio Pozzi, Frank Steffen, Karin Wuertz-Kozak, Lucas A Smolders. JOR spine. 2024 March;7:e1292. [Full Text Article] [PubMed:38222814] [PMC:PMC10782068] Related Antibodies: LS-C388946.
4
Memantine increases the dendritic complexity of hippocampal young neurons in the juvenile brain after cranial irradiation. Georgios Alkis Zisiadis, Androniki Alevyzaki, Elene Nicola, Carlos F D Rodrigues, Klas Blomgren, Ahmed M Osman. Frontiers in oncology. 2023 October;13:1202200. [Full Text Article] [PubMed:37860190]
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NGF Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NGF Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$380
NGF Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NGF Rabbit anti-Human Polyclonal (N-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
NGF Antibody - Western blot testing of NGF antibody and rat brain tissue lysate
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NGF Rabbit anti-Human Polyclonal (aa162-173) Antibody
Xenopus, Bat, Mouse, Goat, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Human
WB
Unconjugated
100 µg/$575
NGF Antibody - Anti-Human ß-NGF Western Blot Unreduced
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NGF Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$326
NGF Antibody - Western Blot (non-reducing) of NGF antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NGF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
NGF Antibody - Western Blot (non-reducing) of NGF antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NGF Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
NGF ELISA Kit
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Sandwich
96-Well Microplate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$699
NGF ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$705
NGF ELISA Kit
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Sandwich
96-Well Strip Plate
Human
3.12 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$733
NGF ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
NGF ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
NGF ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
NGF ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$582
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NGF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
500 µg/$393
NGF Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
NGF Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
NGF Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
NGF Rabbit anti-Human Polyclonal (Leu82) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
NGF ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$685
NGF Antibody - Cell Proliferation Induced by beta-NGF was Neutralized by Human beta-NGF Antibody. Recombinant Human beta-NGF (Catalog #11050-HNAC) stimulates proliferation of TF-1 human erythroleukemic cells. Proliferation elicited by 5 ng/mL of Recombinant Human beta-NGF is neutralized by increasing concentrations of Rabbit Anti-Human beta-NGF neutralizing Monoclonal Antibody (Catalog # 11050-RC6). The IC50 is typically 17-70 ng/mL.
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NGF Rabbit anti-Human Monoclonal (Preservative Free) (RC6) Antibody
Human
Block, ELISA, Neut
Unconjugated, Preservative Free
200 µg/$361; 500 µg/$436
NGF Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with NGFB antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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NGF Rabbit anti-Human Polyclonal (aa84-115) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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NGF Rabbit anti-Human Monoclonal (Preservative Free) (422) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$286; 100 µl/$435
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NGF Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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NGF Mouse anti-Bovine Monoclonal (Biotin) Antibody
Mouse, Bovine, Human, Reptile
ELISA
Biotin Conjugated
200 µg/$442
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NGF Rabbit anti-Mouse Polyclonal Antibody
Chicken, Mouse, Rat, Human
ELISA, Func, IHC, WB
Unconjugated
20 µg/$907
NGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$699
NGF Protein - Active Nerve Growth Factor (NGF) by WB
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E. coli
His, N-Terminal
30/33kDa
10 µg/$307; 50 µg/$602; 200 µg/$1,156; 100 µg/$962; 1 mg/$2,369; 500 µg/$1,876; 5 mg/$4,201; 2 mg/$2,562
Viewing 1-25 of 181 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).