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Neuropeptide Y / NPY

neuropeptide Y

Neuropeptide Y / NPY is a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi.

Gene Name: neuropeptide Y
Family/Subfamily: Pancreatic hormone , not assigned-Pancreatic hormone
Synonyms: NPY, Pro-neuropeptide Y, Neuropeptide Y, PYY4
Target Sequences: NM_000905 NP_000896.1 P01303

Publications (1)

1
Central anorexigenic actions of bile acids are mediated by TGR5. Alessia Perino, Laura A Velázquez-Villegas, Nadia Bresciani, Yu Sun, Qingyao Huang, Valérie S Fénelon, Ashley Castellanos-Jankiewicz, Philippe Zizzari, Giuseppe Bruschetta, Sungho Jin, Aiste Baleisyte, Antimo Gioiello, Roberto Pellicciari, Julijana Ivanisevic, Bernard L Schneider, Sabrina Diano, Daniela Cota, Kristina Schoonjans. Nature metabolism. 2021 May;3:595-603. [Full Text Article] [PubMed:34031591] [PMC:PMC7610881]

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Antibodies (60)
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Neuropeptide Y / NPY (60)
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No (60)
Neuropeptide Y / NPY Antibody - Anti-NPY / Neuropeptide Y antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (3H2) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
Neuropeptide Y / NPY Antibody - Anti-NPY / Neuropeptide Y antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (3F8) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
Neuropeptide Y / NPY Antibody - Anti-NPY / Neuropeptide Y antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (2C10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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Neuropeptide Y / NPY Goat anti-Mouse Polyclonal (aa20-70) Antibody
Xenopus, Rat, Rabbit, Mouse, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
500 µg/$393
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (3B5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$680
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Neuropeptide Y / NPY Rabbit anti-Pig Polyclonal Antibody
Sheep, Rat, Pig, Human
ELISA, IHC, IHC-Fr
Unconjugated
100 µl/$908
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Neuropeptide Y / NPY Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA
Unconjugated
100 µg/$832
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Hamster, Human
IF, IHC, IHC-Fr
Unconjugated
50 µl/$1,079
Neuropeptide Y / NPY Antibody - 1:200 staining rat brain tissue by IHC-P.
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Neuropeptide Y / NPY Antibody - Neuropeptide Y antibody IHC-paraffin: Mouse Brain Tissue.
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal (aa29-64) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Neuropeptide Y / NPY Antibody - Detection limit for recombinant GST tagged NPY is approximately 0.03 ng/ml as a capture antibody.
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (3F11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Neuropeptide Y / NPY Antibody - IHC-P: NPY antibody testing of mouse brain tissue
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal (aa29-59) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Human
IHC, IHC-P
Unconjugated
100 µg/$575
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Neuropeptide Y / NPY Sheep anti-Bovine Polyclonal Antibody
Mouse, Bovine, Rat
IHC, IHC-Fr, RIA
Unconjugated
100 µl/$826
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal (C-terminal) Antibody
Mouse, Rat, Human
ELISA, ICC, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Pig, Human
IF, IHC
Unconjugated
50 µl/$572
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal Antibody
ELISA, ICC, RIA
Unconjugated
100 µl/$587
Neuropeptide Y / NPY Antibody - Immunohistochemistry of paraffin-embedded human lung cancer tissue.
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (GF1) Antibody
Human
ELISA, IHC
Unconjugated
100 µl/$1,146
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Neuropeptide Y / NPY Rabbit anti-Rat Polyclonal (Concentrated) Antibody
Rat
IF, IHC, IHC-Fr
Unconjugated, Concentrated
50 µl/$765
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$341
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Neuropeptide Y / NPY Rabbit anti-Pig Polyclonal Antibody
Pig
ICC, IHC
Unconjugated
50 µl/$572
Neuropeptide Y / NPY Antibody - Immunohistochemistry analysis of NPY antibody in paraffin-embedded human brain tissue.
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal (aa45-94) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Neuropeptide Y / NPY Antibody - IHC of NPY (P94) pAb in paraffin-embedded human brain tissue.
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal (Pro94) Antibody
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).