Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
NCF2 / NOXA2 / p67phox is neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | neutrophil cytosolic factor 2 |
Synonyms: | NCF2, NADPH oxidase activator 2, Neutrophil cytosol factor 2, Neutrophil cytosolic factor 2, NOXA2, p67PHOX, NCF-2, p67-PHOX |
Target Sequences: | NM_000433 NP_000424.2 P19878 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.