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MUC5AC

mucin 5AC, oligomeric mucus/gel-forming

MUC5AC has been isolated from airway secretions. It is found in the protective film of mucus coating the mucosal surfaces of the respiratory tract and the normal gastrointestinal tissues. Mucins are also expressed at low levels in human fetal gut. MUC5AC is involved in epithelial cell proliferation and differentiation in adult airway mucosa and can be used as a marker for hypersecretory disorders. MUC5AC has also been observed in various tumors. For instance it is expressed in primary mucinous ovarian tumors but not in colonic carcinoma metastatic to the ovary, which makes it a useful marker to distinguish the two types of cancer.

Gene Name: mucin 5AC, oligomeric mucus/gel-forming
Synonyms: MUC5AC, Gastric mucin, Major airway glycoprotein, Muc5/5ac, Mucin-5AC, LeB, Lewis B blood group antigen, Tracheobronchial mucin, TBM, MUC-5AC, MUC5
Target Sequences: AJ001403 CAA04738.1 P98088

Publications (6)

1
A beneficiary role for neuraminidase in influenza virus penetration through the respiratory mucus. Yang X, Steukers L, Forier K, Xiong R, Braeckmans K, Van Reeth K, Nauwynck H. PloS one. 2014 9:e110026. (IHC-P; Human) [Full Text Article] [PubMed:25333824] [PMC:PMC4198190]
2
Limbal niche cells: a novel feeder cell for autologous cultivated oral mucosal epithelial transplantation. Duan CY, Xie HT, Zhao XY, Zhang MC. Regenerative medicine. 2019 January;14:49-62. [Full Text Article] [PubMed:30572808] Related Antibodies: LS-C390690.
3
Vagal sensory neurons drive mucous cell metaplasia. Sébastien Talbot, Benjamin Doyle, Junwei Huang, Jo-Chiao Wang, Maryam Ahmadi, David P Roberson, Ajay Yekkirala, Simmie L Foster, Liam E Browne, Bruce P Bean, Bruce D Levy, Clifford J Woolf. The Journal of allergy and clinical immunology. 2020 June;145:1693-1696.e4. [Full Text Article] [PubMed:31954778]
4
Reduced allergic lung inflammation and airway responsiveness in mice lacking the cytoskeletal protein gelsolin. Maya Mikami, Gene T Yocum, Nicola M Heller, Charles W Emala. American journal of physiology. Lung cellular and molecular physiology. 2020 September; [Full Text Article] [PubMed:32902333] [PMC:PMC7789977]
5
Analysis of mucosal mucins separated by SDS-urea agarose polyacrylamide composite gel electrophoresis. Samah M A Issa, Benjamin L Schulz, Nicolle H Packer, Niclas G Karlsson. Electrophoresis. 2011 December;32:3554-63. [Full Text Article] [PubMed:22120911] Related Antibodies: LS-B2434.
6
Vegetable glycerin e-cigarette aerosols cause airway inflammation and ion channel dysfunction. Michael D Kim, Samuel Chung, John S Dennis, Makoto Yoshida, Carolina Aguiar, Sheyla P Aller, Eliana S Mendes, Andreas Schmid, Juan Sabater, Nathalie Baumlin, Matthias Salathe. Frontiers in pharmacology. 2022 October;13:1012723. [Full Text Article] [PubMed:36225570] [PMC:PMC9549247]
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Antibodies (122)
ELISA Kits (19)
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Primary (122)
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Sandwich (12)
Sandwich CLIA (5)
MUC5AC (150)
Human (80)
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Cat (1)
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IHC (45)
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WB (76)
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ELISA (20)
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rabbit (62)
mouse (56)
goat (2)
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B442 (1)
B466 (1)
C7 (7)
CLH2 (6)
MG-31 (4)
MUC5AC/917 (3)
MUC5AC/917 + 45M1 (3)
MUCN5AC (3)
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SPM488 (2)
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aa5568-5654 (1)
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MUC5AC Antibody - Anti-MUC5AC antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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MUC5AC Mouse anti-Human Monoclonal (CLH2) Antibody
Human
ELISA, ICC, IHC, IHC-Fr, IHC-P, IP
Unconjugated
50 µg/$485
MUC5AC Antibody - Anti-MUC5AC antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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MUC5AC Mouse anti-Human Monoclonal (Concentrated) (1-13M1) Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated, Concentrated
50 µg/$460
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MUC5AC Mouse anti-Human Monoclonal (Concentrated) (2-12M1) Antibody
Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated, Concentrated
100 µg/$432
MUC5AC Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using MUC5AC Polyclonal Antibody at dilution of 1:100.
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MUC5AC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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MUC5AC Mouse-Balb/c anti-Human Monoclonal (Concentrated) (2-11M1) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated, Concentrated
100 µg/$432
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$715
MUC5AC ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
15.63 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$764
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
MUC5AC ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
13.7 - 10000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$871
MUC5AC ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Human
13.7 - 10000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$851
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MUC5AC Goat anti-Mouse Polyclonal (aa36-46) Antibody
Mouse
Peptide-ELISA
Unconjugated
100 µg/$401
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MUC5AC Mouse anti-Human Monoclonal (1-13M1) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-Fr
Unconjugated
20 µg/$371; 100 µg/$574
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
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MUC5AC Mouse anti-Human Monoclonal (B442) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Cat, Human, Monkey
ELISA, IHC
Unconjugated
0.5 ml/$328
MUC5AC Antibody - Western blot of recombinant MUC5AC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MUC5AC Rabbit anti-Mouse Polyclonal (aa2040-2149) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
MUC5AC Antibody - Western blot of MUC5AC antibody.
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MUC5AC Rabbit anti-Mouse Polyclonal (aa2040-2149) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
MUC5AC Antibody - SDS-PAGE Analysis of Purified, BSA-Free MUC5AC Antibody (clone 2-11M1). Confirmation of Integrity and Purity of the Antibody.
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MUC5AC Mouse anti-Human Monoclonal (2-11M1) Antibody
Mouse, Bovine, Human, Monkey
Flo, IF, IHC, IHC-Fr
Unconjugated
20 µg/$371; 100 µg/$574
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MUC5AC Mouse anti-Human Monoclonal (MG-31) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$380
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
MUC5AC ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$691
MUC5AC Antibody - Western blot of recombinant MUC5AC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MUC5AC Rabbit anti-Human Polyclonal (aa4944-5030) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217
MUC5AC Antibody - IHC analysis of Mucin 5AC using anti-Mucin 5AC antibody. Mucin 5AC was detected in paraffin-embedded section of human gastric cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-Mucin 5AC Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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MUC5AC Rabbit anti-Human Polyclonal (aa552-567) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25 of 150 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).