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MMP9 / Gelatinase B
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
| Gene Name: | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| Family/Subfamily: | Protease , Metallopeptidase M10A |
| Synonyms: | MMP9, 92kd gelatinase, 92 kDa gelatinase, Matrix metalloproteinase-9, MMP-9, CLG4B, Gelatinase B, GELB, Macrophage gelatinase, MANDP2 |
| Target Sequences: | NM_004994 NP_004985.2 P14780 |
Publications (8)
1
B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression. Nucera C, Porrello A, Antonello ZA, Mekel M, Nehs MA, Giordano TJ, Gerald D, Benjamin LE, Priolo C, Puxeddu E, Finn S, Jarzab B, Hodin RA, Pontecorvi A, Nose V, Lawler J, Parangi S. Proceedings of the National Academy of Sciences of the United States of America. 2010 107:10649-54. (IHC)
[PubMed:20498063]
[PMC:PMC2890809]
2
Is it really necessary to delay intranasal steroid treatment after FESS? An animal study. Bayraktar C, Atmaca S, Guvenc D, Karayigit MO, Atmaca E, Yarim M, Aksoy A. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2013 148:314-23. (IHC-P; Rabbit)
[PubMed:23232827]
3
Tumor necrosis factor-like weak inducer of apoptosis or fn14 deficiency reduce elastase perfusion-induced aortic abdominal aneurysm in mice. Tarín C, Fernández-Laso V, Sastre C, Madrigal-Matute J, Gómez M, Zaragoza C, Egido J, Burkly LC, Martín-Ventura JL, Blanco-Colio LM. Journal of the American Heart Association. 2014 3: (IHC; Mouse)
[Full Text Article]
[PubMed:25092786]
[PMC:PMC4310358]
Related Antibodies: LS-B2486.
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MMP9 / Gelatinase B
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Yes
(2)
MMP9 / Gelatinase B Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µg/$485
MMP9 / Gelatinase B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$440
MMP9 / Gelatinase B Rabbit anti-Human Polyclonal (aa172-221) Antibody
Human
IHC, WB
Unconjugated
100 µl/$397
MMP9 / Gelatinase B Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µg/$485
MMP9 / Gelatinase B Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, IP
Unconjugated
125 µl/$555
MMP9 / Gelatinase B Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P
Unconjugated
100 µg/$538
MMP9 / Gelatinase B Mouse anti-Human Monoclonal (S51-82) Antibody
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
100 µg/$442
MMP9 / Gelatinase B Mouse anti-Rat Monoclonal (aa1-708) (Biotin) (S51-82) Antibody
Mouse, Rat, Human
IHC, IP, WB
Biotin Conjugated
100 µg/$475
Fast Shipping
MMP9 / Gelatinase B Rabbit anti-Human Polyclonal (Internal) Antibody
Bovine, Human
IHC, IHC-P
Unconjugated
50 µg/$460
MMP9 / Gelatinase B Mouse anti-Human Monoclonal (5G3) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$459
MMP9 / Gelatinase B Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
0.1 ml/$295; 0.5 ml/$544; 1 ml/$842
Fast Shipping
MMP9 / Gelatinase B Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
MMP9 / Gelatinase B Mouse anti-Human Monoclonal (4A3) Antibody
Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
MMP9 / Gelatinase B Mouse anti-Human Monoclonal (DY550) (4A3) Antibody
Rat, Human
ELISA, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
MMP9 / Gelatinase B Mouse anti-Human Monoclonal (5G3) Antibody
Mouse, Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µl/$541
MMP9 / Gelatinase B Rabbit anti-Human Monoclonal (Preservative Free) (043) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
MMP9 / Gelatinase B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MMP9 / Gelatinase B Rabbit anti-Human Polyclonal (620-700 aa, C-terminal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MMP9 / Gelatinase B Rabbit anti-Mouse Polyclonal (aa225-390) Antibody
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
100 µl/$275; 200 µl/$303; 500 µl/$395; 1 ml/$441; 2 ml/$533; 5 ml/$900
MMP9 / Gelatinase B Mouse anti-Human Monoclonal (HRP) (SB15c) Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P
HRP Conjugated
1 ml/$501
Cancer
MMP9 / Gelatinase B Rabbit anti-Rat Polyclonal Antibody
Human
IHC
Unconjugated
120 µl/$460
MMP9 / Gelatinase B Rabbit anti-Human Polyclonal (aa644-673) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
MMP9 / Gelatinase B Rabbit anti-Human Polyclonal (aa644-673) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
MMP9 / Gelatinase B Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
MMP9 / Gelatinase B Mouse anti-Human Monoclonal (Preservative Free) (06) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
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