Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Location


Corporate Headquarters

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Telephone Numbers



Customer Service: (800) 227-6666 / (650) 697-3600


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

MMP14

matrix metallopeptidase 14 (membrane-inserted)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Gene Name: matrix metallopeptidase 14 (membrane-inserted)
Family/Subfamily: Protease , Metallopeptidase M10A
Synonyms: MMP14, Membrane type-1 MMP, MT1-MMP, MT1MMP, MT-MMP, MT-MMP 1, Matrix metalloproteinase-14, MMP-14, MMP-X1, MTMMP1
Target Sequences: NM_004995 NP_004986.1 P50281

Publications (2)

1
Cdc42-Dependent Transfer of mir301 from Breast Cancer-Derived Extracellular Vesicles Regulates the Matrix Modulating Ability of Astrocytes at the Blood-Brain Barrier. Golnaz Morad, Cassandra C Daisy, Hasan H Otu, Towia A Libermann, Simon T Dillon, Marsha A Moses. International journal of molecular sciences. 2020 May;21: [Full Text Article] [PubMed:32481745] [PMC:PMC7311991]
2
Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells. David J Lamb, Aleksander Rust, Albin Rudisch, Tobias Glüxam, Nathalie Harrer, Herwig Machat, Ingrid Christ, Florian Colbatzky, Andreas Wernitznig, Annika Osswald, Wolfgang Sommergruber. Oncotarget. 2020 Apr;11:1257-1272. [Full Text Article] [PubMed:32292575] [PMC:PMC7147091] Related Antibodies: LS-C8915.

☰ Filters
Antibodies (89)
ELISA Kits (14)
Proteins (8)
Cell-Based (1)
Custom (4)
Over-Expression Lysate (2)
Primary (89)
Recombinant (6)
Sandwich (9)
MMP14 (111)
Human (87)
Mouse (35)
Rat (32)
Bovine (3)
Dog (1)
Goat (1)
Guinea pig (1)
Hamster (2)
Horse (1)
Monkey (3)
Orangutan (1)
Pig (4)
Rabbit (1)
Sheep (1)
Zebrafish (1)
IHC (32)
IHC-Fr (2)
IHC-P (12)
WB (80)
Flo (8)
Block (1)
ELISA (31)
IF (5)
IP (3)
Peptide-ELISA (4)
rabbit (82)
mouse (6)
goat (1)
Product Group
IHCPlus (3)
IgG (43)
IgG1 (1)
IgG1,k (2)
IgG3,k (1)
IgM (2)
monoclonal mc (5)
polyclonal pc (83)
recombinant monoclonal rmc (1)
133CT15.10.5.1 (1)
6A11D1 (1)
LEM-2/15 (1)
96-Well Microplate (5)
96-Well Strip Plate (9)
APC (3)
APC Conjugated (7)
Azide-free (2)
Biotin Conjugated (8)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (8)
HRP Conjugated (8)
Magnetic beads Conjugated (1)
PE Conjugated (7)
Sepharose Conjugated (1)
Unconjugated (43)
aa112-321 (8)
aa121-487 (8)
aa322-541 (8)
aa145-174 (7)
aa495-523 (7)
C-Terminus (4)
Cleaved-Tyr112 (2)
aa160-173 (2)
aa470-499 (2)
440-520 aa, C-terminal (1)
70-150 aa, Internal (1)
Cleaved (1)
Internal (1)
Membrane type 1 metalloprotease (1)
Pro509 (1)
aa152-163 (1)
aa260-540 (1)
aa319-333 (1)
aa471-520 (1)
aa557-582 (1)
aa567-582 (1)
aa93-142 (1)
No (109)
Yes (2)
Adherent Cell Cultures (1)
Cell Culture Supernatants (2)
Cell Lysates (2)
Plasma (9)
Serum (9)
Tissue Homogenates (5)
GST (1)
His, N-Terminal (1)
His-SUMO (1)
His-T7 (2)
Myc-DDK (Flag) (3)
Human (6)
Mouse (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Select
MMP14 Mouse anti-Human Monoclonal (aa160-173) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$842
MMP14 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
MMP14 Rabbit anti-Human Polyclonal (aa145-174) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
MMP14 Antibody - Confocal immunofluorescence of MMP14 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).
Select
MMP14 Mouse anti-Human Monoclonal (aa470-499) Antibody
Human
IF, WB
Unconjugated
400 µl/$393
MMP14 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$748
MMP14 Protein - Recombinant Matrix Metalloproteinase 14 By SDS-PAGE
Select
E. coli
His, N-Terminal
45.9 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
MMP14 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.63 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
MMP14 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
MMP14 Antibody - Anti-MMP14 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
MMP14 Goat anti-Human Polyclonal (aa152-163) Antibody
Dog, Guinea pig, Bovine, Hamster, Pig, Horse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
MMP14 Antibody - Anti-MMP14 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
MMP14 Rabbit anti-Human Polyclonal (aa160-173) Antibody
Human
IHC, IHC-P
Unconjugated
250 µl/$485
MMP14 Protein
Select
E. coli
His-SUMO
69.8 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
MMP14 Antibody - Immunohistochemical analysis of MMP14 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
MMP14 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
MMP14 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
MMP14 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
MMP14 Antibody - MMP14 / MMP-14 antibody. IHC(P): Human Intestinal Cancer Tissue.
Select
MMP14 Rabbit anti-Human Polyclonal (aa567-582) Antibody
Zebrafish, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
MMP14 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MMP-14 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
MMP14 Rabbit anti-Human Polyclonal (aa471-520) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MMP14 ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
MMP14 Protein - Recombinant Matrix Metalloproteinase 14 By SDS-PAGE
Select
E. coli
His-T7
25.2 kDa
10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
MMP14 Antibody - IHC image of MMP14 Antibody diluted at 1:500 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
MMP14 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
MMP14 Antibody - Western blot of Cleaved-MMP-14 (Y112) antibody
Select
MMP14 Rabbit anti-Human Polyclonal (70-150 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MMP14 Antibody - IF staining of HeLa cells.
Select
MMP14 Mouse anti-Human Recombinant Monoclonal (Membrane type 1 metalloprotease) (LEM-2/15) Antibody
Human
Block, ELISA
Unconjugated
0.2 mg/$540
MMP14 Antibody - 1:200 staining human Oral squamous cells carcinoma sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
MMP14 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MMP14 Antibody - MMP14 antibody Western blot. All lanes: Anti MMP14 at 0.5 ug/ml. Lane 1: Human Placenta Tissue Lysate at 50 ug. Lane 2: HELA Whole Cell Lysate at 40 ug. Lane 3: U87 Whole Cell Lysate at 40 ug. Predicted band size: 55 kD. Observed band size: 55 kD.
Select
MMP14 Rabbit anti-Human Polyclonal (aa557-582) Antibody
Human, Monkey, Orangutan
WB
Unconjugated
10 µg/$318; 100 µg/$470
MMP14 Antibody - Western blot of recombinant MMP14.
Select
MMP14 Rabbit anti-Mouse Polyclonal (aa121-487) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
Select
MMP14 Rabbit anti-Human Polyclonal (aa145-174) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
Select
MMP14 Rabbit anti-Human Polyclonal (C-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
Select
MMP14 Mouse anti-Human Monoclonal (aa319-333) Antibody
Mouse, Goat, Sheep, Bovine, Rat, Hamster, Human, Monkey
ELISA, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$842
Viewing 1-25 of 111 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).