LRP5

low density lipoprotein receptor-related protein 5

Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation.

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Antibodies (45)

ELISA Kits (5)

Proteins (4)

Type

Primary (45)

Recombinant (4)

Sandwich (5)

Target

LRP5 (54)

Reactivity

Human (34)

Mouse (26)

Rat (16)

Hamster (1)

Horse (1)

Monkey (2)

Rabbit (1)

Application

IHC (13)

IHC-P (1)

WB (43)

Flo (2)

ELISA (17)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (40)

mouse (3)

goat (1)

sheep (1)

Isotype

IgG (22)

IgG1 (2)

IgG1,k (1)

Clonality

monoclonal mc (4)

polyclonal pc (41)

Clone

1E9 (1)

2B11 (2)

D80F2 (1)

Format

96-Well Strip Plate (5)

APC (2)

APC Conjugated (4)

Azide-free (2)

Biotin Conjugated (4)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (4)

Unconjugated (21)

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Epitope

aa102-336 (8)

aa769-1016 (8)

aa1163-1190 (7)

aa1538-1567 (7)

C-Terminus (2)

aa1422-1615 (2)

Tyr1473 (1)

aa1000-1250 (1)

aa1178-1189 (1)

aa1201-1215 (1)

aa41-130 (1)

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Publications

No (54)

Sample Type

Cell Lysates (1)

Plasma (4)

Serum (4)

Tissue Homogenates (3)

Tag

GST, N-terminus (1)

His, N-Terminal (1)

His-S (1)

Myc-DDK (Flag) (1)

Species

Human (3)

Rat (1)

Source

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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LRP5 Antibody (aa1538-1567) LS-C100404

Antibody:

LRP5 Rabbit anti-Human Polyclonal (aa1538-1567) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Human LRP5 Protein (Recombinant His, N-Terminal) (aa769-1016) - LS-G15170

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

32.1 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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LRP5 Antibody (aa41-130, clone 1E9) LS-C197626

Antibody:

LRP5 Mouse anti-Human Monoclonal (aa41-130) (1E9) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$335

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LRP5 Antibody (C-Terminus, clone D80F2) LS-C183950

Antibody:

LRP5 Rabbit anti-Human Monoclonal (C-Terminus) (D80F2) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$688

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LRP5 Antibody (aa1201-1215) LS-C313365

Antibody:

LRP5 Rabbit anti-Human Polyclonal (aa1201-1215) Antibody

Reactivity:

Rabbit, Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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LRP5 Antibody LS-C751970

Antibody:

LRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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LRP5 Antibody (aa1422-1615, clone 2B11) LS-C169072

Antibody:

LRP5 Mouse anti-Human Monoclonal (aa1422-1615) (2B11) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

LRP5 Antibody (aa1538-1567) LS-C327771

Antibody:

LRP5 Rabbit anti-Human Polyclonal (aa1538-1567) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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LRP5 Antibody (aa1538-1567, Biotin) LS-C278953

Antibody:

LRP5 Rabbit anti-Human Polyclonal (aa1538-1567) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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LRP5 Antibody (aa1538-1567, FITC) LS-C278956

Antibody:

LRP5 Rabbit anti-Human Polyclonal (aa1538-1567) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

LRP5 Antibody (aa1538-1567, APC) LS-C278951

Antibody:

LRP5 Rabbit anti-Human Polyclonal (aa1538-1567) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

LRP5 Antibody (aa1538-1567, Azide-free, HRP) LS-C278955

Antibody:

LRP5 Rabbit anti-Human Polyclonal (aa1538-1567) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

LRP5 Antibody (aa1538-1567, PE) LS-C278957

Antibody:

LRP5 Rabbit anti-Human Polyclonal (aa1538-1567) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

LRP5 Antibody (aa1000-1250) LS-C408178

Antibody:

LRP5 Rabbit anti-Human Polyclonal (aa1000-1250) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

LRP5 Antibody (C-Terminus) LS-C8514

Antibody:

LRP5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$540; 100 µg/$848

Select

LRP5 Antibody LS-C767931

Antibody:

LRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

LRP5 Antibody (clone 2B11) LS-C759657

Antibody:

LRP5 Mouse anti-Human Monoclonal (2B11) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

LRP5 Antibody (aa1178-1189) LS-C47561

Antibody:

LRP5 Goat anti-Human Polyclonal (aa1178-1189) Antibody

Reactivity:

Mouse, Rat, Hamster, Horse, Human, Monkey

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

LRP5 Antibody LS-C405697

Antibody:

LRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

LRP5 Antibody LS-C402421

Antibody:

LRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

LRP5 Antibody (aa1163-1190) LS-C322719

Antibody:

LRP5 Rabbit anti-Human Polyclonal (aa1163-1190) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

LRP5 Antibody (aa1163-1190, FITC) LS-C262136

Antibody:

LRP5 Rabbit anti-Mouse Polyclonal (aa1163-1190) (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

LRP5 Antibody (aa1163-1190, Azide-free, HRP) LS-C262137

Antibody:

LRP5 Rabbit anti-Mouse Polyclonal (aa1163-1190) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

LRP5 Antibody (aa1163-1190, PE) LS-C262140

Antibody:

LRP5 Rabbit anti-Mouse Polyclonal (aa1163-1190) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

LRP5 Antibody (aa1163-1190, APC) LS-C262134

Antibody:

LRP5 Rabbit anti-Mouse Polyclonal (aa1163-1190) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• FITC
• HRP, Azide-free
• PE
• APC

• Unconjugated
• FITC
• HRP, Azide-free
• More...
  • PE
  • APC

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