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In animal cells, there are A- and B-type lamins, which differ in their length and isoelectric point (pI). Human cells have three differentially regulated genes. B-type lamins are present in every cell. B type lamins, B1 and B2, are expressed from the LMNB1 and LMNB2 genes on 5q23 and 19q13, respectively. A-type lamins are expressed only following gastrulation. Lamin A and C are the most common A-type lamins and are splice variants of the LMNA gene found at 1q21.
Gene Name: | lamin B1 |
Synonyms: | LMNB1, ADLD, Lamin B1, Lamin-B1, LMN, LMNB, LMN2 |
Target Sequences: | NM_005573 NP_005564.1 P20700 |
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