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KPNA2 / Importin Alpha 1
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination.
| Gene Name: | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| Synonyms: | KPNA2, Importin alpha 2, Importin subunit alpha-2, IPOA1, Importin alpha-2 subunit, Karyopherin subunit alpha-2, Importin-alpha-P1, Qip2, RAG cohort 1, SRP1, RCH1, SRP1-alpha, SRP1alpha, Importin alpha 1, Pendulin, RAG cohort protein 1 |
| Target Sequences: | NM_002266 NP_002257.1 P52292 |
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(46)
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(46)
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KPNA2 / Importin Alpha 1
(46)
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(45)
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(22)
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(4)
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(2)
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(25)
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Publications
No
(46)
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal (aa475-C-term) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
KPNA2 / Importin Alpha 1 Goat anti-Human Polyclonal (aa518-529) Antibody
Mouse, Rat, Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
KPNA2 / Importin Alpha 1 Mouse anti-Human Monoclonal (1E8B7) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal (aa475-C-term) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
50 µl/$460
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal (aa157-412) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal (aa157-412) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KPNA2 / Importin Alpha 1 Rat anti-Human Monoclonal (1A6) Antibody
Mouse, Rat, Hamster, Human
ICC, WB
Unconjugated
100 µg/$427
![KPNA2 / Importin Alpha 1 Antibody - karyopherin alpha 2 antibody [C3], C-term detects karyopherin alpha 2 protein at cytoplasm and nucleus by immunofluorescent analysis. HeLa cells were fixed in ice-cold MeOH for 5 min. karyopherin alpha 2 protein stained by karyopherin alpha 2 antibody [C3], C-term diluted at 1:500.](https://lsbio-7d62.kxcdn.com/image2/kpna2-importin-alpha-1-antibody-aa468-529-ls-c185790/138548_4908577.jpg)
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal (aa468-529) Antibody
Mouse, Rat, Human
ICC, WB
Unconjugated
100 µl/$450
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KPNA2 / Importin Alpha 1 Mouse anti-Human Monoclonal (aa2-132) (12K121) Antibody
Human
ICC
Unconjugated
100 µg/$872
KPNA2 / Importin Alpha 1 Mouse anti-Human Monoclonal (aa2-132) (11n120) Antibody
Human
WB
Unconjugated
100 µg/$896
KPNA2 / Importin Alpha 1 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
KPNA2 / Importin Alpha 1 Rat anti-Human Monoclonal (aa116-515) (2G7) Antibody
Human
WB
Unconjugated
0.05 mg/$482
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal (aa323-372) Antibody
Mouse
WB
Unconjugated
100 µl/$424
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
KPNA2 / Importin Alpha 1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$575
KPNA2 / Importin Alpha 1 Goat anti-Human Polyclonal (Biotin) Antibody
Human
Peptide-ELISA, WB
Biotin Conjugated
100 µg/$503
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of 46
product results
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