KMT2A / MLL

lysine (K)-specific methyltransferase 2A

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, it specifically mediates H3K4me, a specific tag for epigenetic transcriptional activation. Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity. Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9'. Required for transcriptional activation of HOXA9. Promotes PPP1R15A-induced apoptosis.

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Products

Antibodies (28)

Type

Primary (28)

Target

KMT2A / MLL (28)

Reactivity

Human (26)

Mouse (6)

Rat (3)

Application

IHC (11)

IHC-P (5)

WB (18)

Flo (1)

ChrIP (1)

ELISA (17)

ICC (1)

IF (1)

IP (6)

Peptide-ELISA (1)

Host

rabbit (23)

mouse (5)

Product Group

IHCPlus (1)

Isotype

IgG (18)

IgG1 (5)

Clonality

monoclonal mc (5)

polyclonal pc (22)

recombinant monoclonal rmc (1)

Clone

10F8D7 (1)

4A5A12 (1)

4H354 (1)

N4.4 (1)

Format

APC Conjugated (2)

Azide-free (2)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (18)

Epitope

aa3879-3908 (7)

C-Terminus (6)

N-Terminus (1)

aa1320-1380 (1)

aa2725-2775 (1)

aa3084-3959 (1)

aa3751-3968 (1)

aa720-780 (1)

Publications

No (28)

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KMT2A / MLL Antibody (N-Terminus) LS-C72739

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$947

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IHC-plus™ KMT2A / MLL Antibody (aa3751-3968, clone 10F8D7) LS-B3471

(4.0) Rating

Antibody:

KMT2A / MLL Mouse anti-Human Monoclonal (aa3751-3968) (10F8D7) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$375

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KMT2A / MLL Antibody (aa2725-2775) LS-C287274

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (aa2725-2775) Antibody

Reactivity:

Human

Applications:

ChrIP, IP, WB

Format:

Unconjugated

Price:

10 µg/$295; 100 µg/$514

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KMT2A / MLL Antibody (aa3084-3959, clone 4H354) LS-C16577

Antibody:

KMT2A / MLL Mouse anti-Human Monoclonal (aa3084-3959) (4H354 ) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

200 µg/$973

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KMT2A / MLL Antibody LS-C150734

Antibody:

KMT2A / MLL Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ICC, IF, IHC, IHC-P

Format:

Unconjugated

Price:

0.1 ml/$386

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KMT2A / MLL Antibody (aa3879-3908) LS-C98665

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (aa3879-3908) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P

Format:

Unconjugated

Price:

400 µl/$393

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KMT2A / MLL Antibody LS-C814058

Antibody:

KMT2A / MLL Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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KMT2A / MLL Antibody (aa3879-3908) LS-C327927

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (aa3879-3908) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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KMT2A / MLL Antibody (aa3879-3908, Biotin) LS-C279641

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (aa3879-3908) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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KMT2A / MLL Antibody (aa3879-3908, FITC) LS-C279642

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (aa3879-3908) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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KMT2A / MLL Antibody (aa3879-3908, APC) LS-C279640

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (aa3879-3908) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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KMT2A / MLL Antibody (aa3879-3908, Azide-free, HRP) LS-C279643

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (aa3879-3908) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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KMT2A / MLL Antibody (aa3879-3908, PE) LS-C279644

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (aa3879-3908) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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KMT2A / MLL Antibody (clone 4A5A12) LS-C828216

Antibody:

KMT2A / MLL Mouse anti-Human Monoclonal (4A5A12) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$459

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KMT2A / MLL Antibody LS-C813904

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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KMT2A / MLL Antibody LS-C779664

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

100 µl/$357

Select

KMT2A / MLL Antibody LS-C803765

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

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KMT2A / MLL Antibody (aa1320-1380) LS-C287024

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (aa1320-1380) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µg/$295; 100 µg/$546

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KMT2A / MLL Antibody (aa720-780) LS-C761981

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (aa720-780) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µg/$295; 100 µg/$546

Select

KMT2A / MLL Antibody (clone N4.4) LS-C760131

Antibody:

KMT2A / MLL Mouse Monoclonal (N4.4) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µg/$471

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KMT2A / MLL Antibody (C-Terminus) LS-C329839

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

200 µl/$734

Select

KMT2A / MLL Antibody (C-Terminus, Biotin) LS-C263242

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

KMT2A / MLL Antibody (C-Terminus, APC) LS-C263241

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• APC

• Unconjugated
• Biotin
• APC

Select

KMT2A / MLL Antibody LS-C836093

Antibody:

KMT2A / MLL Rabbit Recombinant Monoclonal Antibody

Applications:

IP, WB

Format:

Unconjugated

Price:

20 µl/$299; 100 µl/$425

Select

KMT2A / MLL Antibody LS-C667716

Antibody:

KMT2A / MLL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386

Viewing 1-25 of 28 product results

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