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Catalog Number Size Price
LS-C16577-200 200 µg (1 mg/ml) $973 
Antibody

Monoclonal Mouse anti‑Human KMT2A / MLL Antibody (clone 4H354, aa3084‑3959, WB) LS‑C16577

Monoclonal Mouse anti‑Human KMT2A / MLL Antibody (clone 4H354, aa3084‑3959, WB) LS‑C16577

Antibody:
KMT2A / MLL Mouse anti-Human Monoclonal (aa3084-3959) (4H354 ) Antibody
Application:
WB, IP
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$973
LS-C16577-200
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
KMT2A / MLL Mouse anti-Human Monoclonal (aa3084-3959) (4H354 ) Antibody
Application:
WB, IP
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
MLL antibody LS-C16577 is an unconjugated mouse monoclonal antibody to MLL (KMT2A) (aa3084-3959) from human. It is reactive with human and mouse. Validated for IP and WB.
Target
Human KMT2A / MLL
Synonyms
KMT2A | ALL1 | CDK6/MLL fusion protein | FLJ11783 | HRX | HTRX | HTRX1 | Lysine N-methyltransferase 2A | MLL1A | MLL/GAS7 | MLL1 | ALL-1 | MLL | MLL/GAS7 fusion protein | TRX1 | WDSTS | Trithorax-like protein | Zinc finger protein HRX | CXXC7 | MLL-AF4 der(11) fusion protein | MLL/GMPS fusion protein | TET1-MLL
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
4H354
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
MBP fusion protein corresponding to residues 3084-3959 of human mixed lineage leukemia (MLL).
Epitope
aa3084-3959
Specificity
Recognizes the C-terminal proteolytic fragment of human MLL (MLLC), Mr ~180kD. Species cross-reactivity: Human and mouse.
Applications
  • Western blot (0.1 - 1 µg/ml)
  • Immunoprecipitation
Usage
Suitable for use in Western Blot and Immunoprecipitation. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunoprecipitation: Reported by an independent laboratory to immunoprecipitate MLLC from nuclear extracts. The N-terminal fragment, MLLN (300kD), is also co-immunoprecipitated by this antibody.
Presentation
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KMT2A / MLL
Q03164 NM_005933 NP_005924.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/4/2025