KLKB1 / Plasma Kallikrein

kallikrein B, plasma (Fletcher factor) 1

Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.

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Products

Antibodies (41)

Proteins (8)

ELISA Kits (4)

Type

Custom (2)

Over-Expression Lysate (2)

Primary (41)

Recombinant (6)

Sandwich (2)

Target

KLKB1 / Plasma Kallikrein (53)

Reactivity

Human (32)

Mouse (9)

Rat (17)

Bovine (4)

Dog (6)

Gibbon (3)

Horse (6)

Monkey (4)

Pig (3)

Rabbit (3)

Application

IHC (9)

IHC-P (3)

WB (26)

ELISA (25)

IE (2)

IF (4)

Peptide-ELISA (2)

Host

rabbit (36)

mouse (2)

goat (1)

rat (1)

sheep (1)

Product Group

IHCPlus (2)

Isotype

IgG (32)

IgG1 (3)

Clonality

monoclonal mc (3)

polyclonal pc (38)

Clone

13G11 (2)

Format

96-Well Strip Plate (4)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (6)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (1)

Unconjugated (21)

Epitope

aa508-537 (7)

C-Terminus (4)

aa429-478 (4)

310-390 aa, Internal (1)

Internal (1)

aa20-638 (1)

aa341-390 (1)

heavy chain, Cleaved-Arg390 (1)

Publications

No (53)

Sample Type

Cell Culture Supernatants (1)

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

6His, C-terminus (2)

6His, N-terminus (3)

Myc-DDK (Flag) (3)

Species

Human (5)

Rat (2)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Human Cells (1)

Mammalian Cells (1)

Yeast (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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IHC-plus™ KLKB1 / Plasma Kallikrein Antibody LS-B2772

(4.0) Rating

Antibody:

KLKB1 / Plasma Kallikrein Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IE, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$485

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KLKB1 / Plasma Kallikrein Antibody LS-C333980

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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KLKB1 / Plasma Kallikrein Antibody (clone 13G11) LS-C38308

Antibody:

KLKB1 / Plasma Kallikrein Mouse anti-Human Monoclonal (13G11) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$951; 200 µg/$1,609

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KLKB1 / Plasma Kallikrein Antibody (clone 13G11) LS-C83337

Antibody:

KLKB1 / Plasma Kallikrein Mouse anti-Human Monoclonal (13G11) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µg/$686

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KLKB1 / Plasma Kallikrein Antibody LS-C185168

Antibody:

KLKB1 / Plasma Kallikrein Goat anti-Human Polyclonal Antibody

Reactivity:

Human, Monkey

Applications:

ELISA, IE

Format:

Unconjugated

Price:

1 ml/$725

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KLKB1 / Plasma Kallikrein Antibody (aa508-537) LS-C165586

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal (aa508-537) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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KLKB1 / Plasma Kallikrein Antibody LS-C400263

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Rat Polyclonal Antibody

Reactivity:

Rat

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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KLKB1 / Plasma Kallikrein Antibody (HRP) LS-C400269

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Rat Polyclonal (HRP) Antibody

Reactivity:

Rat

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP

• Unconjugated
• HRP

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KLKB1 / Plasma Kallikrein Antibody (310-390 aa, Internal) LS-C380538

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal (310-390 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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KLKB1 / Plasma Kallikrein Antibody LS-C499025

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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KLKB1 / Plasma Kallikrein Antibody (HRP) LS-C499183

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP

• Unconjugated
• HRP

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Human KLKB1 / Plasma Kallikrein (Sandwich ELISA) ELISA Kit - LS-F66776

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.469 - 30 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Rat KLKB1 / Plasma Kallikrein Protein (Recombinant 6His, N-terminus) (aa391-638) - LS-G22996

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

29.8 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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IHC-plus™ KLKB1 / Plasma Kallikrein Antibody (aa341-390) LS-B9277

(4.0) Rating

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal (aa341-390) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$440

Select

Rat KLKB1 / Plasma Kallikrein Protein (Recombinant 6His, N-terminus) (aa391-638) - LS-G20900

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

31.9 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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KLKB1 / Plasma Kallikrein Antibody (C-Terminus) LS-C135182

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Rat Polyclonal (C-Terminus) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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KLKB1 / Plasma Kallikrein Antibody (aa20-638) LS-C37114

Antibody:

KLKB1 / Plasma Kallikrein Rat anti-Mouse Monoclonal (aa20-638) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$941

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KLKB1 / Plasma Kallikrein Antibody (aa508-537) LS-C329738

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal (aa508-537) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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KLKB1 / Plasma Kallikrein Antibody (aa508-537, Azide-free, HRP) LS-C261492

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal (aa508-537) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• HRP, Azide-free

• Unconjugated
• HRP, Azide-free

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KLKB1 / Plasma Kallikrein Antibody (aa429-478) LS-C80752

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal (aa429-478) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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Bovine KLKB1 / Plasma Kallikrein (Sandwich ELISA) ELISA Kit - LS-F66157

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

KLKB1 / Plasma Kallikrein Antibody (Internal) LS-C413411

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$321

Select

KLKB1 / Plasma Kallikrein Antibody LS-C681934

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Rat Polyclonal Antibody

Reactivity:

Rat

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

KLKB1 / Plasma Kallikrein Antibody (HRP) LS-C681936

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Rat Polyclonal (HRP) Antibody

Reactivity:

Rat

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP

• Unconjugated
• HRP

Select

KLKB1 / Plasma Kallikrein Antibody LS-C806593

Antibody:

KLKB1 / Plasma Kallikrein Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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