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| Catalog Number | Size | Price |
|---|---|---|
| LS-C83337-200 | 200 µg (1.6 mg/ml) | $686 |
Monoclonal Mouse anti‑Human KLKB1 / Plasma Kallikrein Antibody (clone 13G11, WB) LS‑C83337
Monoclonal Mouse anti‑Human KLKB1 / Plasma Kallikrein Antibody (clone 13G11, WB) LS‑C83337
Antibody:
KLKB1 / Plasma Kallikrein Mouse anti-Human Monoclonal (13G11) Antibody
Application:
WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
KLKB1 / Plasma Kallikrein Mouse anti-Human Monoclonal (13G11) Antibody
Application:
WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Plasma Kallikrein antibody LS-C83337 is an unconjugated mouse monoclonal antibody to human Plasma Kallikrein (KLKB1). Validated for ELISA and WB.
Target
Human KLKB1 / Plasma Kallikrein
Synonyms
KLKB1 | Fletcher factor deficiency | Fletcher factor | Kininogenin | Plasma kallikrein | PKK deficiency | Plasma kallikrein heavy chain | PPK | Prekallikrein deficiency | Plasma kallikrein light chain | Plasma prekallikrein | Kallikrein 3
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
13G11
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Purified human Kallikrien
Specificity
This antibody recognizes two variants of prekallikrein in human plasma, 88kDa and85kDa, and its activation products kallikrein, the complexes formed by kallikrein with itsendogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and antithrombin III, and 45kDaprekallikrein/kallikrein fragments. It also recognizes prekallikrein and its activation products inchimpanzee, rhesus, and baboon plasmas. The epitope for this antibody is located on theprekallikrein/kallikrein heavy chain and is involved in the interaction between prekallikrein andfactor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by ~60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.
Applications
- Western blot
- ELISA
Usage
May be used in ELISA and Western blots to identify/quantitate prekallikrein and its activation products in plasmas of humans, chimpanzees, rhesus monkeys, and baboons. NOTE: Prekallikrein activation may occur with repeated freezing/thawing (3x or more) of plasma samples obtained from humans or other primates.
Presentation
PBS, pH 7.4
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About KLKB1 / Plasma Kallikrein
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA, Immunoelectrophoresis
Species:
Human
Applications:
Western blot, ELISA
Species:
Human
Applications:
Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/27/2024
Date Requested: 12/27/2024
