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JAG1 / Jagged 1
jagged 1
Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).
| Gene Name: | jagged 1 |
| Synonyms: | JAG1, AGS, AHD, Alagille syndrome, CD339 antigen, HJ1, Jagged1, JAGL1, Jagged, Jagged 1, Protein jagged-1, AWS, CD339, Soluble protein jagged |
| Target Sequences: | NM_000214 NP_000205.1 P78504 |
Publications (7)
1
Differential expression of Notch receptors and their ligands in desmoplastic ameloblastoma. Siar CH, Nakano K, Han PP, Nagatsuka H, Ng KH, Kawakami T. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 2010 39:552-8. (IHC-P; Human)
[PubMed:20337864]
Related Antibodies: LS-B2442.
2
Notch4 overexpression in ameloblastoma correlates with the solid/multicystic phenotype. Siar CH, Nagatsuka H, Chuah KS, Rivera RS, Nakano K, Ng KH, Kawakami T. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2010 110:224-33. (IHC-P; Human)
[PubMed:20659700]
Related Antibodies: LS-B2442.
3
Immunolocalization of notch signaling protein molecules in a maxillary chondrosarcoma and its recurrent tumor. Siar CH, Ha KO, Aung LO, Nakano K, Tsujigiwa H, Nagatsuka H, Ng KH, Kawakami T. European journal of medical research. 2010 15:456-60. (IHC-P; Human)
[Full Text Article]
[PubMed:21156405]
[PMC:PMC3352190]
Related Antibodies: LS-B2442.
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Products
Antibodies
(83)
Proteins
(16)
ELISA Kits
(9)
Type
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(3)
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Primary
(83)
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(14)
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(5)
Target
JAG1 / Jagged 1
(108)
Reactivity
Human
(70)
Mouse
(37)
Rat
(33)
Pig
(8)
Application
IHC
(18)
IHC-Fr
(1)
IHC-P
(7)
WB
(63)
Flo
(20)
ELISA
(24)
ICC
(3)
IF
(9)
Peptide-ELISA
(2)
Host
rabbit
(63)
mouse
(13)
goat
(1)
hamster
(6)
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(1)
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(5)
Isotype
IgG
(30)
IgG1
(5)
IgG1,k
(1)
IgG2a
(2)
IgG2b
(3)
Clonality
monoclonal mc
(18)
polyclonal pc
(65)
Clone
11D68
(1)
11n115
(1)
12G31
(1)
1E12
(1)
6A9B2
(1)
7C7E1
(1)
7C7H2
(1)
HMJ1-29
(1)
OTI1F1
(2)
OTI3A10
(2)
TS106
(1)
Format
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(2)
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(6)
Antibody Pair and Standard
(1)
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(4)
APC Conjugated
(6)
Azide-free
(1)
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(8)
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(1)
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(4)
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(8)
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(7)
PE Conjugated
(7)
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(38)
Epitope
aa836-1047
(10)
aa33-250
(8)
aa470-834
(8)
aa826-1084
(8)
aa1122-1150
(7)
aa523-759
(4)
N-Terminus
(2)
aa110-125
(2)
aa32-296
(2)
aa469-746
(2)
981-1030 aa, Internal
(1)
aa1103-1137
(1)
aa1191-1224
(1)
aa1197-1210
(1)
Publications
No
(106)
Yes
(2)
Sample Type
Cell Culture Supernatants
(1)
Plasma
(5)
Serum
(5)
Tissue Homogenates
(4)
Tag
10His-SUMO, N-terminus + Myc, C-terminus
(1)
Fc
(1)
Fc, C-terminus
(2)
GST, N-terminus
(2)
His
(4)
His-T7
(1)
Human IgG Fc, C-terminus
(1)
Human IgG1 Fc
(1)
Myc-DDK (Flag)
(3)
Species
Human
(12)
Mouse
(3)
Source
293T Cells
(1)
E. coli
(5)
HEK 293 Cells
(4)
Human Cells
(3)
Mammalian Cells
(1)
Wheat Germ Extract
(2)
Purification
Purified
(6)
Low Endotoxin Level
Low endotoxin level
(6)
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal (aa110-125) Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$555
JAG1 / Jagged 1 Goat anti-Human Polyclonal (aa1197-1210) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
500 µg/$606
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal (981-1030 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
JAG1 / Jagged 1 Mouse anti-Human Monoclonal (7C7E1) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$715
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal (aa110-125) Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
500 µg/$1,076
HEK 293 Cells
Human IgG Fc, C-terminus
Less than 0.01 EU/µg protein (determined by LAL method).
~150 kDa (SDS-PAGE)
10 µg/$347; 50 µg/$498
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$485
JAG1 / Jagged 1 Mouse anti-Human Monoclonal (aa32-296) (CF) (11n115) Antibody
Human
Flo
CF Conjugated
100 Tests/$746
JAG1 / Jagged 1 Mouse anti-Human Monoclonal (7C7H2) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal (aa836-1047) Antibody
Mouse, Pig, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal (aa1122-1150) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
JAG1 / Jagged 1 Mouse anti-Human Monoclonal (APC) (11D68) Antibody
Human
Flo
APC Conjugated
100 Tests/$907
HEK 293 Cells
Human IgG1 Fc
Less than 0.1 EU/µg protein (determined by LAL method).
~150kDa (SDS-PAGE)
50 µg/$470; 10 µg/$347
JAG1 / Jagged 1 Mouse anti-Human Monoclonal (6A9B2) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal (aa1122-1150) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal (aa469-746) Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$332
JAG1 / Jagged 1 Mouse anti-Human Monoclonal (1E12) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$423
JAG1 / Jagged 1 Mouse anti-Human Monoclonal (aa32-296) (TS106) Antibody
Human
Flo
Unconjugated
100 µg/$930
JAG1 / Jagged 1 Rabbit anti-Mouse Polyclonal (aa1191-1224) Antibody
Mouse
WB
Unconjugated
400 µl/$393
JAG1 / Jagged 1 Rabbit anti-Mouse Polyclonal (aa826-1084) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
25 µl/$304
JAG1 / Jagged 1 Rabbit anti-Human Polyclonal (aa470-834) Antibody
Rat, Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
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