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ITGB7 / Integrin Beta 7
integrin, beta 7
Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.
| Gene Name: | integrin, beta 7 |
| Family/Subfamily: | Integrin , not assigned-Integrin |
| Synonyms: | ITGB7, Integrin Beta 7, Integrin beta 7 subunit, Integrin beta-7, Integrin, beta 7, INTEGRINB7, Integrin B7, Integrin B 7 |
| Target Sequences: | NM_000889 NP_000880.1 P26010 |
Publications (1)
1
IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen. Ohmori K, Luo Y, Jia Y, Nishida J, Wang Z, Bunting KD, Wang D, Huang H. Journal of immunology (Baltimore, Md. : 1950). 2009 182:2835-41.
[PubMed:19234178]
[PMC:PMC2756103]
Related Antibodies: LS-C41345.
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ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ITGB7 / Integrin Beta 7 Mouse anti-Human Monoclonal (aa20-723) Antibody
Human
ELISA, Flo, ICC
Unconjugated
100 µg/$896
ITGB7 / Integrin Beta 7 Rat anti-Human Monoclonal (FIB504) Antibody
Mouse, Human
Flo
Unconjugated
100 µg/$285
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal (aa737-765) Antibody
Human
WB
Unconjugated
400 µl/$393
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC-P, WB
Unconjugated
50 µl/$460
![ITGB7 / Integrin Beta 7 Antibody - Immunofluorescence of monoclonal antibody to ITGB7 on HeLa cell . [antibody concentration 10 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/itgb7-integrin-beta-7-antibody-clone-8d3-ls-c197559/145460_4911406.jpg)
ITGB7 / Integrin Beta 7 Mouse anti-Human Monoclonal (8D3) Antibody
Human
ELISA, IF
Unconjugated
100 µg/$423
ITGB7 / Integrin Beta 7 Rabbit anti-Rabbit Recombinant Monoclonal (FIB504) Antibody
Rabbit, Mouse, Human
Block, Flo, IF
Unconjugated
0.2 mg/$540
ITGB7 / Integrin Beta 7 Sheep anti-Human Polyclonal (aa20-723) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$930
ITGB7 / Integrin Beta 7 Rabbit anti-Rabbit Recombinant Monoclonal (FIB27) Antibody
Mouse, Human
Block, Flo, IP
Unconjugated
0.2 mg/$540
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ITGB7 / Integrin Beta 7 Hamster anti-Human Monoclonal Antibody
Human
Flo, IHC, IP
Unconjugated
100 µg/$854
ITGB7 / Integrin Beta 7 Hamster anti-Human Monoclonal (HRP) Antibody
Human
Flo, IHC, IP
HRP Conjugated
100 µl/$1,079
ITGB7 / Integrin Beta 7 Hamster anti-Human Monoclonal (Biotin) Antibody
Human
Flo, IHC, IP
Biotin Conjugated
100 µl/$1,079
ITGB7 / Integrin Beta 7 Hamster anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IP
FITC Conjugated
100 µl/$1,079
ITGB7 / Integrin Beta 7 Hamster anti-Human Monoclonal (APC) Antibody
Human
Flo, IHC, IP
APC Conjugated
100 µl/$1,079
ITGB7 / Integrin Beta 7 Hamster anti-Human Monoclonal (PE) Antibody
Human
Flo, IHC, IP
PE Conjugated
100 µl/$1,079
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal (aa737-765) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal (aa737-765) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal (aa737-765) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
ITGB7 / Integrin Beta 7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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