Rabbit ITGB7 / Integrin Beta 7

Rabbit

Rabbit, Human, Mouse (tested or 100% immunogen sequence identity)

IgG,k Recombinant Monoclonal

FIB504

Unconjugated

Protein A affinity purified

Unmodified

FIB504 was prepared by immunizing rats with TK1 cells.

FIB504 recognizes an epitope on intergin beta-7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.

• Immunofluorescence
• Flow Cytometry
• Blocking

Applications should be user optimized.

PBS, 0.02% Proclin 300

Store undiluted at 4°C for up to 3 months. Aliquot and store at -20°C for long term storage.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P26010 NCBI: NM_000889 NP_000880.1