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ITGB2 / CD18
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.
| Gene Name: | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| Family/Subfamily: | Integrin , not assigned-Integrin |
| Synonyms: | ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1 |
| Target Sequences: | NM_000211 NP_000202.3 P05107 |
Publications (3)
1
Multiple receptors trigger human NK cell-mediated cytotoxicity against porcine chondrocytes. Sommaggio R, Cohnen A, Watzl C, Costa C. Journal of immunology (Baltimore, Md. : 1950). 2012 188:2075-83.
[PubMed:22287712]
Related Antibodies: LS-C40959.
2
Actinobacillus pleuropneumoniae exotoxin ApxI induces cell death via attenuation of FAK through LFA-1. Siou-Cen Li, Yu-Tsen Cheng, Ching-Yang Wang, Jia-Ying Wu, Zeng-Weng Chen, Jyh-Perng Wang, Jiunn-Horng Lin, Shih-Ling Hsuan. Scientific reports. 2021 January;11:1753. [Full Text Article]
[PubMed:33462305]
[PMC:PMC7813829]
Related Antibodies: LS-C312785.
3
Expression of adhesion, attachment and invasion markers in eutopic and ectopic endometrium: a link to the aetiology of endometriosis. Sundqvist J, Andersson KL, Scarselli G, Gemzell-Danielsson K, Lalitkumar PG. Human reproduction (Oxford, England). 2012 Sep;27:2737-46. [Full Text Article]
[PubMed:22767451]
Related Antibodies: LS-B1849.
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Products
Antibodies
(186)
Type
Primary
(186)
Target
ITGB2 / CD18
(186)
Reactivity
Human
(140)
Mouse
(43)
Rat
(29)
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(2)
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(6)
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(1)
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(5)
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(36)
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(24)
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(19)
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(112)
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(85)
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(30)
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(22)
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(21)
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(42)
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(79)
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(5)
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(28)
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(14)
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aa24-54
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aa404-769
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aa720-769
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aa732-748
(1)
aa86-99
(1)
Publications
No
(183)
Yes
(3)
ITGB2 / CD18 Mouse anti-Human Monoclonal (MEM-48) Antibody
Human
Flo, Func, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
0.05 mg/$460
ITGB2 / CD18 Mouse anti-Human Monoclonal (aa534-546) (Low Endotoxin) (MEM-48) Antibody
Human
Flo, Func, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Low Endotoxin
0.05 mg/$460
ITGB2 / CD18 Rabbit anti-Human Polyclonal (aa732-748) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ITGB2 / CD18 Mouse anti-Human Monoclonal (TS1/18) Antibody
Pig, Human
Flo
Unconjugated
100 µg/$283
ITGB2 / CD18 Rabbit anti-Human Polyclonal (aa720-769) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ITGB2 / CD18 Rat anti-Human Monoclonal (YFC118.3) Antibody
Human
Flo, IF, IHC, IHC-Fr, IP
Unconjugated
0.1 mg/$385
ITGB2 / CD18 Rat anti-Mouse Monoclonal (M18/2) Antibody
Mouse
Flo, Func, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$267
ITGB2 / CD18 Mouse anti-Dog Monoclonal (CA1.4E9) Antibody
Dog
Flo, IF, IHC-Fr, IP
Unconjugated
0.1 mg/$402
ITGB2 / CD18 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
ITGB2 / CD18 Mouse anti-Human Monoclonal (IB4) Antibody
Human
Flo, Func
Unconjugated
100 µg/$411
ITGB2 / CD18 Mouse anti-Human Monoclonal (FITC) (IB4) Antibody
Human
Flo, Func
FITC Conjugated
120 Tests/$446
ITGB2 / CD18 Mouse anti-Human Monoclonal (Activation Epitope) (Preservative Free) (MEM-148) Antibody
Human
Flo, IP, WB
Unconjugated, Preservative Free
1 mg/$801
ITGB2 / CD18 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
400 µl/$393
ITGB2 / CD18 Rat anti-Human Monoclonal (Low Endotoxin) (YFC118.3) Antibody
Human
Flo, IF, IHC, IHC-Fr, IP
Unconjugated, Low Endotoxin
0.5 mg/$671
ITGB2 / CD18 Rabbit anti-Human Polyclonal (N-Terminus) (Sepharose) Antibody
Mouse, Rat, Human
IP
Sepharose Conjugated
100 µg/$399
ITGB2 / CD18 Rat anti-Human Monoclonal Antibody
Dog, Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$562; 200 µg/$755
ITGB2 / CD18 Rat anti-Mouse Monoclonal (FITC) (M18/2) Antibody
Mouse
Flo
FITC Conjugated
50 µg/$270; 100 µg/$322; 500 µg/$495
ITGB2 / CD18 Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
WB
Unconjugated
100 µl/$299
ITGB2 / CD18 Mouse anti-Human Monoclonal Antibody
Human
Flo, ICC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ITGB2 / CD18 Rat anti-Mouse Monoclonal (C71/16) Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
0.5 mg/$380
ITGB2 / CD18 Rat anti-Mouse Monoclonal (Azide-free, Low Endotoxin) (C71/16) Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Azide-free, Low Endotoxin
0.5 mg/$427
ITGB2 / CD18 Rat anti-Mouse Monoclonal (Low Endotoxin) (M18/2) Antibody
Mouse
Flo, Func, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Low Endotoxin
0.1 mg/$295
ITGB2 / CD18 Rat anti-Mouse Monoclonal (Azide-free, Low Endotoxin) (M18/2) Antibody
Mouse
Flo, IHC, IP, WB
Unconjugated, Azide-free, Low Endotoxin
50 µg/$248; 500 µg/$333; 1 mg/$433
ITGB2 / CD18 Goat anti-Human Polyclonal (aa86-99) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
ITGB2 / CD18 Rabbit anti-Human Polyclonal (N-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
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product results
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