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ITGA6/Integrin Alpha 6/CD49f
integrin, alpha 6
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | integrin, alpha 6 |
| Family/Subfamily: | Integrin , not assigned-Integrin |
| Synonyms: | ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B |
| Target Sequences: | NM_000210 NP_000201.2 P23229 |
Publications (7)
1
Reduced migration, altered matrix and enhanced TGFbeta1 signaling are signatures of mouse keratinocytes lacking Sdc1. Stepp MA, Liu Y, Pal-Ghosh S, Jurjus RA, Tadvalkar G, Sekaran A, Losicco K, Jiang L, Larsen M, Li L, Yuspa SH. Journal of cell science. 2007 120:2851-63.
[PubMed:17666434]
2
Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Horwitz KB, Dye WW, Harrell JC, Kabos P, Sartorius CA. Proceedings of the National Academy of Sciences of the United States of America. 2008 105:5774-9. (IHC)
[PubMed:18391223]
[PMC:PMC2311360]
3
Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Nardella C, Carracedo A, Alimonti A, Hobbs RM, Clohessy JG, Chen Z, Egia A, Fornari A, Fiorentino M, Loda M, Kozma SC, Thomas G, Cordon-Cardo C, Pandolfi PP. Science signaling. 2009 2:ra2.
[PubMed:19176516]
[PMC:PMC2906144]
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ITGA6/Integrin Alpha 6/CD49f
(118)
Reactivity
Human
(89)
Mouse
(33)
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(9)
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(10)
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(9)
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(2)
Application
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(67)
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(18)
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(9)
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(61)
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(55)
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(20)
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(17)
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(12)
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(31)
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(46)
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(51)
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(36)
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monoclonal mc
(64)
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(47)
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129CT49.6.5
(4)
450-30A
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(11)
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(16)
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(12)
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900-980 aa, C-terminal
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aa1082-1110
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aa93-148
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light chain, Cleaved-Glu942
(1)
Publications
No
(117)
Yes
(1)
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(1)
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(2)
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(1)
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(3)
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Human
(3)
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(1)
Source
293T Cells
(1)
E. coli
(1)
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(2)
Wheat Germ Extract
(1)
ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (Internal) Antibody
Horse, Human
IHC, IHC-P
Unconjugated
50 µg/$460
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (aa324-620) (129CT49.6.5) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
Fast Shipping
ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (aa1043-1072) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
ITGA6/Integrin Alpha 6/CD49f Rat anti-Human Monoclonal (RPE) (NKI-GoH3) Antibody
Human
Flo
RPE Conjugated
100 Tests/$485
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Rat Monoclonal (Mab-5A) Antibody
Rat
ELISA, Flo, IF, IHC, IHC-Fr
Unconjugated
0.25 mg/$486
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Rat Monoclonal (RPE) (Mab-5A) Antibody
Rat
Flo
RPE Conjugated
100 Tests/$502
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, WB
Unconjugated
100 µg/$558
ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (aa1082-1110) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (4C1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal Antibody
Mouse, Dog, Bovine, Rat, Pig, Human
IF, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Mouse Monoclonal (4F10) Antibody
Mouse, Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$642
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Chicken Monoclonal Antibody
Chicken
ICC, IHC, IP, WB
Unconjugated
100 µg/$867
ITGA6/Integrin Alpha 6/CD49f Rat anti-Human Monoclonal Antibody
Mouse, Dog, Pig, Cynomolgus, Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$562; 200 µg/$755
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (Biotin) (BQ16) Antibody
Human
Flo, IHC, WB
Biotin Conjugated
100 µg/$446
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (FITC) (BQ16) Antibody
Human
Flo, IHC, WB
FITC Conjugated
120 Tests/$446
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (RPE) (BQ16) Antibody
Human
Flo, IHC, WB
RPE Conjugated
120 Tests/$511
ITGA6/Integrin Alpha 6/CD49f Rat anti-Human Monoclonal (GoH3) Antibody
Mouse, Human
Flo, IHC, IP
Unconjugated
0.1 mg/$424
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (129CT49.6.5) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, Flo, IF, IHC, WB
Biotin Conjugated
200 µl/$952
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (APC) (129CT49.6.5) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (Azide-free) (HRP) (129CT49.6.5) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ITGA6/Integrin Alpha 6/CD49f Rat anti-Mouse Monoclonal Antibody
Mouse
Flo, ICC, IHC, IHC-Fr, IP
Unconjugated
100 µg/$872
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of 118
product results
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