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ILT3 / LILRB4

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4

ILT3 / LILRB4 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: LILRB4, CD85K, CD85k antigen, ILT-3, ILT3, LIR-5, LIR5, HM18
Target Sequences: NM_006847 NP_006838.3 Q8NHJ6

Publications (1)

1
NCR(+)ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures. Carrega P, Loiacono F, Di Carlo E, Scaramuccia A, Mora M, Conte R, Benelli R, Spaggiari GM, Cantoni C, Campana S, Bonaccorsi I, Morandi B, Truini M, Mingari MC, Moretta L, Ferlazzo G. Nature communications. 2015 6:8280. (WB; Human) [Full Text Article] [PubMed:26395069] Related Antibodies: LS-C261904.

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Products
Antibodies (31)
Primary (31)
ILT3 / LILRB4 (31)
Human (23)
Mouse (9)
Rat (7)
IHC (1)
IHC-P (2)
WB (21)
Flo (9)
ELISA (11)
IF (2)
Peptide-ELISA (1)
rabbit (21)
mouse (10)
IgG (11)
IgG1 (4)
IgG1,k (1)
IgG2a (5)
monoclonal mc (10)
polyclonal pc (21)
05 (4)
293622 (1)
293623 (3)
ZM4.1 (1)
APC (1)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (2)
CF Conjugated (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (2)
PE Conjugated (4)
Preservative Free (1)
Unconjugated (13)
aa24-206 (8)
aa44-73 (7)
Extracellular Domain (2)
180-260 aa, Internal (1)
aa201-250 (1)
No (30)
Yes (1)
Select
ILT3 / LILRB4 Mouse anti-Human Monoclonal (Extracellular Domain) (293622) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$919
ILT3 / LILRB4 Antibody - Immunofluorescence analysis of A549 cells, using LILRB4 Antibody. The picture on the right is blocked with the synthesized peptide.
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ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa201-250) Antibody
Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ILT3 / LILRB4 Antibody - Western blot of extracts of various cell lines, using LILRB4 antibody.
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ILT3 / LILRB4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC-P, WB
Unconjugated
20 µl/$275; 100 µl/$389
ILT3 / LILRB4 Antibody - Flow cytometric analysis of Human LILRB4(CD85k) expression on human whole blood monocytes. Cells were stained with purified anti-Human LILRB4(CD85k), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
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ILT3 / LILRB4 Mouse anti-Human Monoclonal (Preservative Free) (05) Antibody
Human
Flo
Unconjugated, Preservative Free
100 µl/$412
ILT3 / LILRB4 Antibody - Western blot of recombinant ILT3 / LILRB4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ILT3 / LILRB4 Rabbit anti-Mouse Polyclonal (aa24-206) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
ILT3 / LILRB4 Antibody - Western blot of recombinant ILT3 / LILRB4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ILT3 / LILRB4 Rabbit anti-Mouse Polyclonal (aa24-206) (PE) Antibody
Mouse, Rat
WB
PE Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
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ILT3 / LILRB4 Mouse anti-Human Monoclonal (CF) Antibody
Human
Flo
CF Conjugated
100 Tests/$649
Select
ILT3 / LILRB4 Mouse anti-Human Monoclonal (Extracellular Domain) (293623) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$962
Select
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (180-260 aa, Internal) Antibody
Human
ELISA, IF
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ILT3 / LILRB4 Antibody - Immunohistochemistry of paraffin-embedded human lung tissue at dilution 1:100
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ILT3 / LILRB4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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ILT3 / LILRB4 Mouse anti-Human Monoclonal (APC) (293623) Antibody
Human
Flo
APC Conjugated
100 Tests/$824
ILT3 / LILRB4 Antibody - Western blot All Lanes:LILRB4 antibody at 4.39ug/ml Lane 1:MCF-7 whole cell lysate Lane 2:A549 whole cell lysate Secondary Goat polyclonal to rabbit at 1/10000 dilution Predicted band size: 49kDa Observed band size: 49kDa,40kDa (We are unsure as to the identity of this extra band)
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ILT3 / LILRB4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$294; 100 µl/$360
Select
ILT3 / LILRB4 Mouse anti-Human Monoclonal (ZM4.1) Antibody
Human
Flo
Unconjugated
100 µg/$483
Select
ILT3 / LILRB4 Mouse anti-Human Monoclonal (PE) (293623) Antibody
Human
Flo
PE Conjugated
100 Tests/$771
ILT3 / LILRB4 Antibody - Flow cytometric analysis of Human LILRB4(CD85k) expression on human whole blood monocytes. Cells were stained with FITC-conjugated anti-Human LILRB4(CD85k). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
Select
ILT3 / LILRB4 Mouse anti-Human Monoclonal (FITC) (05) Antibody
Human
Flo
FITC Conjugated
25 Tests/$278; 100 Tests/$376
ILT3 / LILRB4 Antibody - Flow cytometric analysis of Human LILRB4(CD85k) expression on human whole blood monocytes. Cells were stained with PE-conjugated anti-Human LILRB4(CD85k). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
Select
ILT3 / LILRB4 Mouse anti-Human Monoclonal (PE) (05) Antibody
Human
Flo
PE Conjugated
25 Tests/$278; 100 Tests/$376
ILT3 / LILRB4 Antibody - Flow cytometric analysis of Human LILRB4(CD85k) expression on human whole blood monocytes. Cells were stained with APC-conjugated anti-Human LILRB4(CD85k). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
Select
ILT3 / LILRB4 Mouse anti-Human Monoclonal (APC) (05) Antibody
Human
Flo
APC Conjugated
25 Tests/$278; 100 Tests/$376
ILT3 / LILRB4 Antibody - LILRB4 Antibody western blot of MDA-MB435 cell line lysates (35 ug/lane). The LILRB4 antibody detected the LILRB4 protein (arrow).
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ILT3 / LILRB4 Rabbit anti-Human Polyclonal (aa44-73) Antibody
Human
WB
Unconjugated
400 µl/$393
ILT3 / LILRB4 Antibody
Select
ILT3 / LILRB4 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).