order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
IL4R / CD124
interleukin 4 receptor
IL4R / CD124 is the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
| Gene Name: | interleukin 4 receptor |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL4R, CD124, CD124 antigen, IL-4RA, IL4R nirs variant 1, IL4RA, Interleukin 4 receptor, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha |
| Target Sequences: | NM_000418 NP_000409.1 P24394 |
Your search did not match any products.
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
