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IL4

interleukin 4

IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene Name: interleukin 4
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL4, B cell growth factor 1, B-cell stimulatory factor 1, B_cell stimulatory factor 1, BCGF1, BSF-1, Binetrakin, BCGF-1, Interleukin 4, Interleukin-4, Pitrakinra, BSF1, IL-4
Target Sequences: NM_000589 NP_000580.1 P05112

Publications (3)

1
Phosphoantigen-activated V gamma 2V delta 2 T cells antagonize IL-2-induced CD4+CD25+Foxp3+ T regulatory cells in mycobacterial infection. Gong G, Shao L, Wang Y, Chen CY, Huang D, Yao S, Zhan X, Sicard H, Wang R, Chen ZW. Blood. 2009 113:837-45. [PubMed:18981295] [PMC:PMC2630269] Related Antibodies: LS-C41019.
2
Modulation of Binge-like Ethanol Consumption by IL-10 Signaling in the Basolateral Amygdala. S Alex Marshall, Kyle H McKnight, Allyson K Blose, Donald T Lysle, Todd E Thiele. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2017 June;12:249-259. [Full Text Article] [PubMed:27640210] [PMC:PMC5357210] Related Antibodies: LS-C745952.
3
Delivery of Interleukin-4-Encoding Lentivirus Using Multiple-Channel Bridges Enhances Nerve Regeneration. S Ahmed Ali, John E Hanks, Aaron W Stebbins, Osama Alkhalili, Samantha T Cohen, Jessica Y Chen, Dominique R Smith, Courtney M Dumont, Lonnie D Shea, Norman D Hogikyan, Eva L Feldman, Michael J Brenner. The Laryngoscope. 2020 December;130:2802-2810. [Full Text Article] [PubMed:32220076] [PMC:PMC7893531] Related Antibodies: LS-C408858.

☰ Filters
Products
Antibodies (251)
Primary (251)
IL4 (251)
Human (114)
Mouse (66)
Rat (36)
Bovine (6)
Chicken (8)
Chimpanzee (6)
Dog (14)
Goat (1)
Horse (1)
Monkey (17)
Mustelid (1)
Pig (18)
Rabbit (10)
Sheep (1)
IHC (32)
IHC-Fr (6)
IHC-P (8)
WB (196)
Flo (38)
ELISA (96)
ELISPOT (1)
Func (4)
IF (9)
IP (7)
Neut (12)
Peptide-ELISA (3)
Stim (1)
SwELISA (5)
rabbit (165)
mouse (37)
goat (3)
guinea pig (8)
rat (38)
Product Group
IHCPlus (4)
IgG (71)
IgG,k (1)
IgG1 (14)
IgG1,k (23)
IgG2a (7)
IgG2a,k (1)
IgG2b (5)
IgG2b,k (12)
monoclonal mc (75)
polyclonal pc (174)
recombinant monoclonal rmc (2)
04 (2)
05 (1)
11B11 (9)
3D11 (1)
401 (1)
404 (1)
860A 4B3 (1)
8D4-8 (1)
BVD4-1D11 (3)
BVD6-24G2 (3)
CC303 (3)
CC313 (1)
CC314 (1)
MP4-25D2 (10)
APC (13)
APC Conjugated (17)
Azide-free (6)
Biotin Conjugated (35)
Cy3 Conjugated (13)
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aa25-153 (18)
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aa25-133 (8)
aa25-147 (8)
aa26-136 (8)
aa26-147 (8)
aa66-120 (8)
aa122-150 (7)
C-Terminus (5)
aa74-123 (4)
IL-4 (2)
Internal (2)
Ala59 (1)
C-terminal (1)
aa1-153 (1)
aa10-59 (1)
aa108-153 (1)
aa123-140 (1)
aa72-88 (1)
aa72-98 (1)
No (248)
Yes (3)
IL4 Antibody - Anti-IL-4 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IL4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
IL4 Antibody - IL4 Antibody IHC of formalin-fixed and paraffin-embedded tonsil followed by peroxidase-conjugated secondary antibody and DAB staining.
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IL4 Rabbit anti-Human Polyclonal (aa122-150) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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IL4 Rat anti-Human Monoclonal (PerCP) (MP4-25D2) Antibody
Human
ELISA, Flo, IHC
PerCP Conjugated
25 µg/$236; 100 µg/$251
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IL4 Mouse anti-Human Monoclonal (860A 4B3) Antibody
Human
ELISA, SwELISA
Unconjugated
500 µg/$780
IL4 Antibody
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IL4 Mouse anti-Human Monoclonal (8D4-8) Antibody
Human, Monkey
ELISA, Flo, IHC, IP
Unconjugated
50 µg/$264
IL4 Antibody - Immunohistochemistry of paraffin-embedded human liver injury tissue.
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IL4 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
IL4 Antibody - 1:100 staining human uterus tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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IL4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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IL4 Rat anti-Mouse Monoclonal (PE) Antibody
Mouse
Flo
PE Conjugated
500 µl/$1,009
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IL4 Mouse anti-Bovine Monoclonal (PE) Antibody
Goat, Dog, Sheep, Bovine, Pig, Mustelid
Flo
PE Conjugated
100 Tests/$984
IL4 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
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IL4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC-P
Unconjugated
50 µg/$460
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IL4 Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, IHC, IP, WB
Unconjugated
500 µg/$763; 1 mg/$957
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IL4 Goat anti-Rabbit Polyclonal Antibody
Rabbit
ELISA, WB
Unconjugated
0.1 mg/$596
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IL4 Mouse anti-Pig Monoclonal Antibody
Pig
ELISA
Unconjugated
500 µg/$631
Select
IL4 Mouse anti-Bovine Monoclonal (CC313) Antibody
Bovine
ELISA
Unconjugated
0.5 mg/$571
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IL4 Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, Flo, IF, WB
Unconjugated
500 µg/$548
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IL4 Mouse anti-Bovine Monoclonal (FITC) (CC303) Antibody
Bovine
Flo
FITC Conjugated
0.1 mg/$652
IL4 Antibody - Western blot of mouse IL-4 recombinant protein probed with Rat anti-Mouse Interleukin-4  (RAT ANTI MOUSE INTERLEUKIN-4).
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IL4 Rat anti-Mouse Monoclonal (BVD4-1D11) Antibody
Mouse
ELISA, Flo, IHC, IHC-Fr, WB
Unconjugated
0.5 mg/$534
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IL4 Rabbit anti-Human Polyclonal (aa122-150) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
IL4 Antibody - Western blot - Anti-IL-4 Antibody
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IL4 Rabbit anti-Human Polyclonal (aa25-153) Antibody
Human
ELISA, IHC, IHC-P, IP, Neut, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL4 Antibody - IL4 antibody. IHC(P): Human Tonsil Tissue.
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IL4 Rabbit anti-Human Polyclonal (aa72-88) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL4 Antibody - Western Blot (non-reducing) of IL-4 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL4 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
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IL4 Mouse anti-Bovine Monoclonal (CC303) Antibody
Bovine
ELISA, Flo
Unconjugated
0.5 mg/$714
IL4 Antibody - Splenocytes from 8 week old mice pre-immunized with OVA/IFA were treated with medium only as negative control for 36 hours in mouse IL-4 ELISPOT assay.
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IL4 Rat anti-Mouse Monoclonal (11B11) Antibody
Mouse
ELISA, ELISPOT
Unconjugated
50 µg/$270; 500 µg/$402
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IL4 Rabbit anti-Dog Polyclonal Antibody
Dog
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
IL4 Antibody - Western Blot; Sample: Recombinant protein.
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IL4 Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
100 µl/$310; 200 µl/$353; 500 µl/$495; 1 ml/$567
Viewing 1-25 of 251 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).