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Vector Laboratories, Inc.
6737 Mowry Ave
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IL3RA / CD123

interleukin 3 receptor, alpha (low affinity)

IL3RA / CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

Gene Name: interleukin 3 receptor, alpha (low affinity)
Family/Subfamily: Interleukin
Synonyms: IL3RA, CD123 antigen, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL3R, IL3RY, CD123, HIL-3Ra, IL-3R-alpha, IL-3RA, IL3RAY, IL3RX
Target Sequences: NM_002183 NP_002174.1 P26951

Publications (1)

1
Basophils and the T helper 2 environment can promote the development of lupus nephritis. Charles N, Hardwick D, Daugas E, Illei GG, Rivera J. Nature medicine. 2010 16:701-7. [PubMed:20512127] [PMC:PMC2909583] Related Antibodies: LS-C40981.

☰ Filters
Products
Proteins (15)
Fusion (1)
Over-Expression Lysate (2)
Recombinant (12)
IL3RA / CD123 (15)
No (15)
6His, C-terminus (2)
Fc, C-terminus (2)
Fc-AVI, C-terminus (1)
GST, N-terminus (1)
His (3)
His, N-Terminal (1)
His,C-terminus (1)
Myc-DDK (Flag) (3)
Cynomolgus (1)
Human (10)
Mouse (3)
293T Cells (1)
CHO Cells (1)
E. coli (3)
HEK 293 Cells (3)
Human (2)
Human Cells (1)
Mammalian Cells (3)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (7)
IL3RA / CD123 Protein - Recombinant Interleukin 3 Receptor Alpha By SDS-PAGE
Select
E. coli
His, N-Terminal
17.3 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
IL3RA / CD123 Protein - Purified recombinant protein IL3RA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
41.2 kDa
20 µg/$1,107
IL3RA / CD123 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
35.75 kDa
10 µg/$479; 25 µg/$670
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
35.9 kDa
100 µg/$793; 1 mg/$4,191
IL3RA / CD123 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
43.33 kDa
20 µg/$150
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
34.5 kDa
100 µg/$1,007; 1 mg/$5,333
IL3RA / CD123 Protein - Recombinant Human IL-3 Receptor Subunit Alpha/IL-3RA/CD123 (C-6His)
Select
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.9 kDa
10 µg/$290; 50 µg/$446
IL3RA / CD123 Protein - Recombinant Cynomolgus IL-3 Receptor Subunit Alpha/IL-3RA/CD123 (C-Fc)
Select
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.6 kDa
10 µg/$290; 50 µg/$446
IL3RA / CD123 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
43.33 kDa
100 µg/$494
IL3RA / CD123 Protein
Select
CHO Cells
None
61.6 kDa
25 µg/$575
Select
Mammalian Cells
Fc, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$288; 50 µg/$442; 500 µg/$1,585
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
59.9 kDa
10 µg/$288; 50 µg/$436
Select
Mammalian Cells
Fc-AVI, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
61.8 kDa
20 µg/$416; 100 µg/$910
IL3RA / CD123 Protein - Recombinant Interleukin 3 Receptor Alpha By SDS-PAGE
Select
E. coli
His
18.1 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
IL3RA / CD123 Protein - Recombinant Interleukin 3 Receptor Alpha By SDS-PAGE
Select
E. coli
His
19.4 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).