Target
IL3RA / CD123
Synonyms
IL3RA | CD123 antigen | IL-3 receptor subunit alpha | IL-3R subunit alpha | IL3R | IL3RY | CD123 | HIL-3Ra | IL-3R-alpha | IL-3RA | IL3RAY | IL3RX
Modifications
Preservative Free
Conjugations
Unconjugated
Region
Extracellular domain of mature human CD123 fused to murine IgG2a Fc.
Predicted Molecular Weight
61.6 kDa
AA Sequence
tkedpnppitnlrmkakaqqltwdlnrnvtdiecvkdadysmpavnnsycqfgaislcevtnytvrvanppfstwilfpensgkpwagaenltcwihdvdflscswavgpgapadvqydlylnvanrrqqyeclhyktdaqgtrigcrfddisrlssgsqsshilvrgrsaafgipctdkfvvfsqieiltppnmtakcnkthsfmhwkmrshfnrkfryelqiqkrmqpviteqvrdrtsfqllnpgtytvqirarervyeflsawstpqrfecdqeegantrawrtsllialgtllalvcvfvic
Expression System
CHO Cells
Source Species
Hamster-Chinese
Usage Summary
A soluble molecule consisting of the extracellular domain of mature human CD123 fused to murine IgG2a Fc. Mature CD123(EC) (307 aa): tkedpnppitnlrmkakaqqltwdlnrnvtdiecvkdadysmpavnnsycqfgaislcevtnytvrvanppfstwilfpensgkpwagaenltcwihdvdflscswavgpgapadvqydlylnvanrrqqyeclhyktdaqgtrigcrfddisrlssgsqsshilvrgrsaafgipctdkfvvfsqieiltppnmtakcnkthsfmhwkmrshfnrkfryelqiqkrmqpviteqvrdrtsfqllnpgtytvqirarervyeflsawstpqrfecdqeegantrawrtsllialgtllalvcvfvic, Linking amino acids (2aa): gt, Murine IgG2aFc (233aa): eprgptikpcppckcpapnllggpsvfifppkikdvlmislspivtcvvvdvseddpdvqiswfvnnvevhtaqtqthredynstlrvvsalpiqhqdwmsgkefkckvnnkdlpapiertiskpkgsvrapqvyvlpppeeemtkkqvtltcmvtdfmpediyvewtnngktelnykntepvldsdgsyfmysklrvekknwvernsyscsvvheglhnhhttksfsrtpgk. Predicted nonglycosylated monomeric weight: 61.6 kd. Human CD123-muIg was reactive in EIA utilizing coated recombinant IL-3 capture, detection with GAM/HRP and TMB/H2O2 substrate. Binding was easily observed at 200ng/ml.
Presentation
50 mM Sodium Phosphate, pH 7.5, 150 mM NaCl, 100 mM KCl
Storage
Store at 2°C to 5°C for up to 6 months. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee