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IL17RA
interleukin 17 receptor A
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Gene Name: | interleukin 17 receptor A |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL17RA, CANDF5, CD217 antigen, CDw217, CD217, HIL-17R, IL-17RA, IL17R, Interleukin-17 receptor A, IL-17 receptor, IL-17 receptor A, Interleukin 17 receptor, Interleukin 17 receptor A |
| Target Sequences: | NM_014339 NP_055154.3 Q96F46 |
Publications (3)
1
COX-2 modulates mammary tumor progression in response to collagen density. Esbona K, Inman D, Saha S, Jeffery J, Schedin P, Wilke L, Keely P. Breast cancer research : BCR. 2016 18:35. (WB; Human)
[Full Text Article]
[PubMed:27000374]
[PMC:PMC4802888]
2
Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation. Tao Peng, R Savanh Chanthaphavong, Sijie Sun, James A Trigilio, Khamsone Phasouk, Lei Jin, Erik D Layton, Alvason Z Li, Colin E Correnti, Willem De van der Schueren, Julio Vazquez, Diana R O'Day, Ian A Glass, David M Knipe, Anna Wald, Lawrence Corey, Jia Zhu. The Journal of experimental medicine. 2017 August;214:2315-2329. [Full Text Article]
[PubMed:28663436]
[PMC:PMC5551564]
3
Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies. Travis K Hughes, Marc H Wadsworth nd, Todd M Gierahn, Tran Do, David Weiss, Priscila R Andrade, Feiyang Ma, Bruno J de Andrade Silva, Shuai Shao, Lam C Tsoi, Jose Ordovas-Montanes, Johann E Gudjonsson, Robert L Modlin, J Christopher Love, Alex K Shalek. Immunity. 2020 October;53:878-894.e7. [Full Text Article]
[PubMed:33053333]
[PMC:PMC7562821]
Related Antibodies: LS-C359381.
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IL17RA Mouse anti-Human Monoclonal (aa186-267) (49M4D2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 mg/$386
IL17RA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
IL17RA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
![IL17RA Antibody - Immunohistochemistry-Paraffin: IL17RA Antibody (49M4D2) [Azide Free] - Formalin-fixed, paraffin-embedded human spleen stained with IL-17RA antibody (1 ug/ml), peroxidase-conjugate and DAB chromogen. TMA was used for this test. This image was taken for the unmodified form of this product. Other forms have not been tested.](https://lsbio-7d62.kxcdn.com/image2/il17ra-antibody-aa186-267-clone-49m4d2-azide-free-ls-c366912/257438_5007678.jpg)
IL17RA Mouse anti-Human Monoclonal (aa186-267) (Azide-free) (49M4D2) Antibody
Human
IHC, IHC-P, WB
Unconjugated, Azide-free
0.1 mg/$386
IL17RA Goat anti-Mouse Polyclonal (aa353-364) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µg/$503
IL17RA Rat anti-Mouse Monoclonal (aa32-322) (APC) (12K116) Antibody
Mouse
Flo
APC Conjugated
100 Tests/$884
IL17RA Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Sandwich
96-Well Microplate
Human
12.35 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
IL17RA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
60 µl/$460
IL17RA Goat anti-Mouse Polyclonal (Extracellular Domain) Antibody
Mouse
ELISA, Flo, WB
Unconjugated
100 µg/$929
IL17RA Mouse anti-Human Monoclonal (aa33-320) Antibody
Human
ELISA, WB
Unconjugated
500 µg/$1,089
IL17RA Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
IL17RA Rabbit anti-Human Monoclonal (FITC) (004) Antibody
Human
Flo
FITC Conjugated
25 Tests/$278; 100 Tests/$421
IL17RA Mouse anti-Human Monoclonal (6H1B1) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$699
IL17RA Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
IL17RA Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL17RA Rabbit anti-Mouse Polyclonal (aa721-747) Antibody
Mouse
ELISA, WB
Unconjugated
200 µl/$734
IL17RA Rabbit anti-Mouse Polyclonal (aa721-747) (APC) Antibody
Mouse
ELISA, WB
APC Conjugated
200 µl/$952
IL17RA Rabbit anti-Mouse Polyclonal (aa721-747) (PE) Antibody
Mouse
ELISA, WB
PE Conjugated
200 µl/$952
IL17RA Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
25 µg/$288; 100 µg/$414
IL17RA Rabbit anti-Human Polyclonal (110-190 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
IL17RA Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IL17RA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL17RA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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product results
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