Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
IL-10
interleukin 10
IL-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
| Gene Name: | interleukin 10 |
| Family/Subfamily: | Hormone , not assigned-Hormone |
| Synonyms: | IL10, CSIF, GVHDS, IL-10, IL10A, Interleukin-10, Interleukin 10, TGIF |
| Target Sequences: | NM_000572 NP_000563.1 P22301 |
Publications (6)
1
Antibodies to human IL-10 neutralize ebvIL-10-mediated cytokine suppression but have no effect on cmvIL-10 activity. Brodeur ND, Spencer JV. Virus research. 2010 153:265-8. (WB; Human)
[Full Text Article]
[PubMed:20728483]
[PMC:PMC3769974]
Related Antibodies: LS-C47137.
2
Skin-Derived Mesenchymal Stem Cells Alleviate Atherosclerosis via Modulating Macrophage Function. Li Q, Sun W, Wang X, Zhang K, Xi W, Gao P. Stem cells translational medicine. 2015 November;4:1294-301. (Mouse)
[Full Text Article]
[PubMed:26400926]
[PMC:PMC4622403]
Related Antibodies: LS-B4913.
3
PPAR? agonist rosiglitazone alters the temporal and spatial distribution of inflammation during abdominal aortic aneurysm formation. Wen-Da Wang, Rui Sun, Yue-Xin Chen. Molecular medicine reports. 2018 September;18:3421-3428. [Full Text Article]
[PubMed:30066924]
Related Antibodies: LS-C331959.
☰ Filters
Products
Antibodies
(174)
ELISA Kits
(90)
Proteins
(70)
Type
Competitive EIA
(2)
Custom
(2)
Development Kit
(11)
Over-Expression Lysate
(2)
Primary
(174)
Recombinant
(68)
Sandwich
(70)
Sandwich CLIA
(5)
Target
IL-10
(334)
Reactivity
Human
(91)
Mouse
(41)
Rat
(48)
Bovine
(14)
Camel
(1)
Canine
(4)
Cat
(1)
Chicken
(4)
Cow
(9)
Dog
(20)
Equine
(1)
Feline
(1)
Goat
(3)
Guinea pig
(4)
Hamster
(1)
Hamster-Golden Syrian
(1)
Horse
(20)
Monkey
(1)
Pig
(8)
Rabbit
(12)
Rhesus monkey
(1)
Sheep
(2)
Swine
(1)
Application
IHC
(11)
IHC-Fr
(2)
IHC-P
(9)
WB
(150)
Flo
(17)
ELISA
(41)
ICC
(1)
IF
(2)
IP
(1)
Neut
(1)
Peptide-ELISA
(1)
SwELISA
(1)
Host
rabbit
(97)
mouse
(53)
goat
(1)
guinea pig
(8)
rat
(15)
Product Group
Coronavirus Antibodies Proteins cDNAs
(242)
Coronavirus Detection
(88)
Cytokine Release Syndrome
(330)
Cytokine Release Syndrome Antibodies
(172)
Cytokine Release Syndrome Proteins
(70)
DevKit Core
(4)
DevKit DuoPlus
(7)
ELISA Kits for Cytokine Release Syndrome Targets
(88)
IHCPlus
(1)
PathPlus Cancer
(1)
Isotype
IgG
(23)
IgG1
(15)
IgG1,k
(14)
IgG2a
(4)
IgG2a,k
(16)
IgG2b,k
(15)
Clonality
monoclonal mc
(68)
polyclonal pc
(104)
recombinant monoclonal rmc
(2)
Clone
03
(1)
12
(1)
15B9-1-2
(1)
3C12C12
(1)
945A5D11
(1)
CC320
(2)
IL10/2651R
(2)
JES3-12G8
(1)
JES3-9D7
(4)
JES5-16E3
(7)
JES5-2A5
(1)
Format
1000 Wells
(3)
12 x 8-Well Microstrips
(5)
200 Wells
(1)
96-Well Microplate
(16)
96-Well Strip Plate
(58)
Animal-free
(1)
Antibody Pair and Standard
(7)
APC
(15)
APC Conjugated
(18)
Azide-free
(1)
Biotin Conjugated
(19)
Carrier-free
(1)
Cy3 Conjugated
(15)
Cy7 Conjugated
(15)
FITC Conjugated
(13)
HRP Conjugated
(15)
Low Endotoxin
(1)
PE Conjugated
(18)
Preservative Free
(11)
RPE Conjugated
(1)
Unconjugated
(60)
Epitope
aa19-178
(56)
aa21-181
(8)
aa27-53
(1)
Publications
No
(329)
Yes
(5)
Sample Type
Cell Culture Supernatants
(47)
Cell Lysates
(30)
Plasma
(80)
Serum
(80)
Tissue Homogenates
(55)
Tag
10His, C-terminus
(2)
10His, N-terminus + Myc, C-terminus
(1)
6His, N-terminus
(1)
6His-B2M, N-terminus
(1)
6His-SUMO, N-terminus
(1)
GST
(2)
GST, N-terminus
(1)
His
(9)
His, N-Terminal
(5)
His,C-terminus
(1)
His-GST
(2)
His-GST, N-terminus
(1)
His-S
(1)
His-T7
(4)
Human IgG1 Fc
(1)
Human Mutant IgG1 Fc
(1)
Mouse Mutant IgG2a Fc
(1)
Myc-DDK (Flag)
(3)
Species
Bovine
(3)
Dog
(2)
Horse
(1)
Human
(31)
Marmoset
(1)
Mouse
(14)
Pig
(1)
Rabbit
(2)
Rat
(7)
Rhesus monkey
(6)
Sheep
(1)
Source
293F Cells
(4)
293T Cells
(1)
Baculovirus
(2)
CHO Cells
(6)
E. coli
(35)
HEK 293 Cells
(6)
Human
(1)
Human Cells
(1)
Mammalian Cells
(2)
NS1 Cells
(1)
Wheat Germ Extract
(2)
Yeast
(6)
Purification
Purified
(28)
Low Endotoxin Level
Low endotoxin level
(27)
Biologically Active
Biologically active
(24)
Animal-free
Animal-free
(1)
Cancer
IL-10 Rat anti-Mouse Monoclonal (JES5-2A5) Antibody
Mouse, Goat
ELISA, Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$495
IL-10 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
IL-10 Rat anti-Human Monoclonal (JES3-12G8) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
0.5 mg/$534
IL-10 Rat anti-Mouse Monoclonal (15B9-1-2) Antibody
Mouse
ELISA, WB
Unconjugated
500 µg/$326
IL-10 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IP, WB
Unconjugated
500 µg/$763; 1 mg/$957
IL-10 Mouse anti-Bovine Monoclonal (Low Endotoxin) (CC320) Antibody
Bovine
ELISA, Flo
Unconjugated, Low Endotoxin
0.5 mg/$705
IL-10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL-10 Rabbit anti-Dog Polyclonal (aa21-181) Antibody
Dog
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
IL-10 Mouse anti-Human Monoclonal (3C12C12) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$328
IL-10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
IL-10 Rabbit anti-Human Polyclonal (aa27-53) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Sandwich
96-Well Microplate
Mouse
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
Sandwich
96-Well Microplate
Human
2.344 - 150 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
Sandwich
96-Well Strip Plate
Chicken
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$757
Sandwich
96-Well Microplate
Chicken
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$590
Sandwich CLIA
96-Well Strip Plate
Mouse
1.37 - 1000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$871
Sandwich
96-Well Strip Plate
Hamster
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Rabbit
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
293F Cells
His, N-Terminal
20kDa
10 µg/$321; 50 µg/$692; 200 µg/$1,284; 100 µg/$1,082; 1 mg/$2,544; 500 µg/$2,042; 5 mg/$4,831; 2 mg/$2,736
Sandwich
96-Well Strip Plate
Rat
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
Sandwich
96-Well Strip Plate
Monkey
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL-10 Rabbit anti-Rat Polyclonal (aa19-178) Antibody
Rat
ELISA, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25
of 334
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
