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IAPP / Amylin
islet amyloid polypeptide
IAPP / Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. This protein also exhibits an bactericidal, antimicrobial activity.
| Gene Name: | islet amyloid polypeptide |
| Synonyms: | IAPP, Diabetes-associated peptide, Islet amyloid polypeptide, AMYLIN, IAP, Insulinoma amyloid peptide |
| Target Sequences: | NM_000415 NP_000406.1 P10997 |
Publications (6)
1
Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. Despa S, Sharma S, Harris TR, Dong H, Li N, Chiamvimonvat N, Taegtmeyer H, Margulies KB, Hammock BD, Despa F. Journal of the American Heart Association. 2014 3: (WB; Human)
[Full Text Article]
[PubMed:25146704]
[PMC:PMC4310392]
Related Antibodies: LS-C20521.
2
Extracellular vesicles from human pancreatic islets suppress human islet amyloid polypeptide amyloid formation. Ribeiro D, Horvath I, Heath N, Hicks R, Forslöw A, Wittung-Stafshede P. Proceedings of the National Academy of Sciences of the United States of America. 2017 October;114:11127-11132. [Full Text Article]
[PubMed:28973954]
[PMC:PMC5651775]
3
Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins. Pietro Sormanni, Francesco A Aprile, Michele Vendruscolo. Proceedings of the National Academy of Sciences of the United States of America. 2015 August;112:9902-7. [Full Text Article]
[PubMed:26216991]
[PMC:PMC4538631]
Related Antibodies: LS-B35.
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IAPP / Amylin
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Publications
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(61)
Yes
(3)
IAPP / Amylin Mouse anti-Human Monoclonal (Supernatant) (R10/99) Antibody
Human
IF, IHC, IHC-Fr, IHC-P
Unconjugated, Supernatant
0.05 ml/$555
IAPP / Amylin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
IAPP / Amylin Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$801
IAPP / Amylin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
IAPP / Amylin Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IAPP / Amylin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$801
IAPP / Amylin Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
IAPP / Amylin Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat, Cat
IF, IHC
Unconjugated
50 µl/$572
IAPP / Amylin Rabbit anti-Human Polyclonal Antibody
Guinea pig, Rat, Pig, Cat, Human
IHC, IHC-Fr, IHC-P
Unconjugated
50 µl/$1,130
IAPP / Amylin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
IAPP / Amylin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
IAPP / Amylin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
IAPP / Amylin Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
IAPP / Amylin Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
IAPP / Amylin Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
IAPP / Amylin Rabbit anti-Human Polyclonal (C-term) Antibody
Human
ELISA, WB
Unconjugated
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
IAPP / Amylin Rabbit anti-Human Polyclonal (C-term) (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
IAPP / Amylin Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
IAPP / Amylin Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
IAPP / Amylin Rabbit anti-Human Polyclonal (aa1-13) Antibody
Human
ELISA
Unconjugated
100 µg/$755
IAPP / Amylin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IAPP / Amylin Rabbit anti-Human Polyclonal (His28) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
IAPP / Amylin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
IAPP / Amylin Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
IAPP / Amylin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
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